antipyrine has been researched along with Infections, Plasmodium in 3 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antipyrine and metronidazole were administered as a cocktail to young (4 weeks old) male Wistar rats (N = 12 for each treatment) to investigate the effect of malaria infection due to the rodent parasite Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of the two compounds in vivo." | 7.68 | Effect of malaria infection and endotoxin-induced fever on the metabolism of antipyrine and metronidazole in the rat. ( Edwards, G; Glazier, AP; Ismail, S; Kokwaro, GO; Ward, SA, 1993) |
| "We have shown that malaria infection can impair selectively the formation of antipyrine metabolites in the rat." | 7.68 | The effect of malaria infection on antipyrine metabolite formation in the rat. ( Edwards, G; Mansor, SM; Ward, SA, 1991) |
| "Antipyrine and metronidazole were administered as a cocktail to young (4 weeks old) male Wistar rats (N = 12 for each treatment) to investigate the effect of malaria infection due to the rodent parasite Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of the two compounds in vivo." | 3.68 | Effect of malaria infection and endotoxin-induced fever on the metabolism of antipyrine and metronidazole in the rat. ( Edwards, G; Glazier, AP; Ismail, S; Kokwaro, GO; Ward, SA, 1993) |
| "We have shown that malaria infection can impair selectively the formation of antipyrine metabolites in the rat." | 3.68 | The effect of malaria infection on antipyrine metabolite formation in the rat. ( Edwards, G; Mansor, SM; Ward, SA, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kokwaro, GO | 1 |
| Ismail, S | 1 |
| Glazier, AP | 1 |
| Ward, SA | 2 |
| Edwards, G | 2 |
| Mansor, SM | 1 |
| Dupont, V | 1 |
| Vachon, F | 1 |
| Emile, J | 1 |
| Carbon, C | 1 |
3 other studies available for antipyrine and Infections, Plasmodium
| Article | Year |
|---|---|
Effect of malaria infection and endotoxin-induced fever on the metabolism of antipyrine and metronidazole in the rat.
Topics: Animals; Antipyrine; Body Temperature; Disease Models, Animal; Endotoxins; Fever; Lipopolysaccharide | 1993 |
The effect of malaria infection on antipyrine metabolite formation in the rat.
Topics: Animals; Antipyrine; Biotransformation; Cytochrome P-450 Enzyme System; Malaria; Male; Microsomes, L | 1991 |
[Cerebral malaria with deep coma and acute renal insufficiency. Cure after 6 days of respiratory resuscitation associated with specific treatment of the malaria].
Topics: Acute Kidney Injury; Antipyrine; Brain Diseases; Coma; Humans; Malaria; Male; Middle Aged; Neurologi | 1967 |