antipyrine has been researched along with Hyperthyroidism in 10 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Hyperthyroidism: Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 mg/kg body weight) and antipyrine clearance with a one-sample technique." | 7.70 | Liver volume, portal vein flow, and clearance of indocyanine green and antipyrine in hyperthyroidism before and after antithyroid treatment. ( Andersen, V; Court-Payen, M; Mølholm Hansen, J; Prip, A; Sletting, S; Sonne, J, 1999) |
| "5 mg/kg body weight) and antipyrine clearance with a one-sample technique." | 3.70 | Liver volume, portal vein flow, and clearance of indocyanine green and antipyrine in hyperthyroidism before and after antithyroid treatment. ( Andersen, V; Court-Payen, M; Mølholm Hansen, J; Prip, A; Sletting, S; Sonne, J, 1999) |
| "The salivary kinetics and rates of metabolite formation of antipyrine were studied in 6 hyperthyroid and 6 hypothyroid out-patients on 2 occasions, on admission and when T3 and T4 levels had returned to normal after treatment with carbimazole (hyperthyroidism) or l-thyroxine (hyperthyroidism)." | 3.67 | Influence of mild thyroid dysfunction on antipyrine clearance and metabolite formation in man. ( Breimer, DD; Doodeman, PJ; Teunissen, MW; van der Veen, EA, 1984) |
| "1 In order to study the relative contribution of hepatic drug metabolizing enzymes and hepatic blood flow to the clearance of drugs in the hyperthyroid state, the disposition kinetics of two model compounds (antipyrine and propranolol) were examined in thyroid-fed dogs as compared to euthyroid and phenobarbitone-pretreated animals." | 3.66 | Absence of changes in drug disposition and catecholamine sensitivity in the hyperthyroid dog. ( Ishizaki, T; Tawara, K, 1980) |
| "The metabolism of phenytoin was studied in 9 hyperthyroid and 7 hypothyroid patients before and after treatment with either antithyroid drugs or 1-thyroxine." | 3.66 | Unaltered metabolism of phenytoin in thyroid disorders. ( Kampmann, JP; Lumholtz, BI; Mølholm Hansen, J; Siersbaek-Nielsen, K; Skovsted, L, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Teunissen, MW | 1 |
| van der Veen, EA | 1 |
| Doodeman, PJ | 1 |
| Breimer, DD | 1 |
| Obel, AO | 1 |
| Ng'ang'a, J | 1 |
| Gitau, W | 1 |
| Ishizaki, T | 1 |
| Tawara, K | 1 |
| Andersen, V | 1 |
| Sonne, J | 1 |
| Court-Payen, M | 1 |
| Sletting, S | 1 |
| Prip, A | 1 |
| Mølholm Hansen, J | 2 |
| Skovsted, L | 1 |
| Kampmann, JP | 1 |
| Lumholtz, BI | 1 |
| Siersbaek-Nielsen, K | 1 |
| Vesell, ES | 1 |
| Shapiro, JR | 1 |
| Passananti, T | 1 |
| Jorgensen, H | 1 |
| Shively, CA | 1 |
| Saenger, P | 1 |
| Rifkind, AB | 1 |
| New, MI | 1 |
| Crooks, J | 1 |
| Hedley, AJ | 1 |
| Macnee, C | 1 |
| Stevenson, IH | 1 |
| Gugler, R | 2 |
| Eichelbaum, M | 2 |
| Schneider-Deters, C | 1 |
| Bodem, G | 2 |
| Dengler, HJ | 2 |
| Schneider-Deters, D | 1 |
10 other studies available for antipyrine and Hyperthyroidism
| Article | Year |
|---|---|
Influence of mild thyroid dysfunction on antipyrine clearance and metabolite formation in man.
Topics: Adult; Aged; Antipyrine; Biotransformation; Female; Half-Life; Humans; Hyperthyroidism; Hypothyroidi | 1984 |
Antipyrine half-life in hyperthyroidism.
Topics: Adult; Antipyrine; Female; Half-Life; Humans; Hyperthyroidism; Male; Middle Aged; Thyroid Function T | 1981 |
Absence of changes in drug disposition and catecholamine sensitivity in the hyperthyroid dog.
Topics: Animals; Antipyrine; Catecholamines; Dogs; Female; Heart Rate; Hyperthyroidism; Kinetics; Male; Phar | 1980 |
Liver volume, portal vein flow, and clearance of indocyanine green and antipyrine in hyperthyroidism before and after antithyroid treatment.
Topics: Adult; Aged; Aged, 80 and over; Antipyrine; Antithyroid Agents; Blood Flow Velocity; Body Weight; Fe | 1999 |
Unaltered metabolism of phenytoin in thyroid disorders.
Topics: Adult; Aged; Antipyrine; Female; Half-Life; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Ag | 1978 |
Altered plasma half-lives of antipyrine, propylthiouracil, and methimazole in thyroid dysfunction.
Topics: Adult; Aged; Antipyrine; Biotransformation; Female; Half-Life; Humans; Hyperthyroidism; Hypothyroidi | 1975 |
Changes in drug metabolism in children with thyroid disorders.
Topics: Adolescent; Antipyrine; Child; Child, Preschool; Half-Life; Humans; Hyperthyroidism; Hypothyroidism; | 1976 |
Proceedings: Changes in drug metabolizing ability in thyroid disease.
Topics: Antipyrine; Carbimazole; Humans; Hyperthyroidism; Methimazole; Thyroid Diseases; Triiodothyronine | 1973 |
[Influence of thyroid function on human drug metabolism].
Topics: Antipyrine; Humans; Hyperthyroidism; Hypothyroidism; Pharmaceutical Preparations; Thyroid Gland | 1973 |
Influence of thyroid status on plasma half-life of antipyrine in man.
Topics: Administration, Oral; Adult; Aged; Antipyrine; Biotransformation; Cholesterol; Female; Half-Life; He | 1974 |