antipyrine has been researched along with Hyperbilirubinemia, Hereditary in 7 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Hyperbilirubinemia, Hereditary: Inborn errors of bilirubin metabolism resulting in excessive amounts of bilirubin in the circulating blood, either because of increased bilirubin production or because of delayed clearance of bilirubin from the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gilbert disease was diagnosed in a 15-year-old boy on the basis of the clinical pattern and the changing drug-metabolizing capacity of the liver-enzyme apparatus, which was drug-induced." | 1.27 | Non-specific drug-metabolizing enzyme activity in Gilbert disease. ( Csanádi, J; Gyurkovits, K; Szeleczki, T; Várkonyi, A, 1984) |
| "The pharmacokinetic parameters of antipyrine (AP) were examined in 45 normal healthy subjects (18 heavy smokers, 5 mild smokers, and 22 nonsmokers) and in 12 patients with Gilbert's syndrome (GS), amongst whom 2 mild and 1 heavy smokers were included." | 1.27 | Antipyrine clearance in patients with Gilbert's syndrome. ( Chiba, K; Ishizaki, T; Sasaki, T, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Várkonyi, A | 2 |
| Szeleczki, T | 2 |
| Csanádi, J | 2 |
| Gyurkovits, K | 2 |
| Ishizaki, T | 1 |
| Chiba, K | 1 |
| Sasaki, T | 1 |
| Habior, A | 1 |
| Narang, AP | 1 |
| Datta, DV | 1 |
| Nakajima, O | 1 |
| Orme, ML | 1 |
| Davies, L | 1 |
| Breckenridge, A | 1 |
1 trial available for antipyrine and Hyperbilirubinemia, Hereditary
| Article | Year |
|---|---|
Comparison of in-vivo and in-vitro drug metabolism in patients with Gilbert's syndrome.
Topics: Adult; Antipyrine; Bilirubin; Clinical Trials as Topic; Female; Gilbert Disease; Humans; Hyperbiliru | 1982 |
6 other studies available for antipyrine and Hyperbilirubinemia, Hereditary
| Article | Year |
|---|---|
Non-specific drug-metabolizing enzyme activity in Gilbert disease.
Topics: Adolescent; Antipyrine; Bilirubin; Gilbert Disease; Glucaric Acid; Glucuronosyltransferase; Histocyt | 1984 |
Antipyrine clearance in patients with Gilbert's syndrome.
Topics: Adult; Antipyrine; Female; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Male; Metabolic | 1984 |
[Usefulness of the determination of bile acids in the blood and antipyrine elimination in the diagnosis of minimal liver damage].
Topics: Adult; Antipyrine; Bile Acids and Salts; Female; Gilbert Disease; Half-Life; Humans; Hyperbilirubine | 1983 |
[Non-specific drug-metabolizing enzyme capacity in Gilbert's disease].
Topics: Adolescent; Antipyrine; Benzhydryl Compounds; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditar | 1983 |
[Gilbert's syndrome and incomplete conjugation of bilirubin].
Topics: Antipyrine; Bile; Bilirubin; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Isomerism | 1985 |
Increased glucuronidation of bilirubin in man and rat by administration of antipyrine (phenazone).
Topics: Adolescent; Adult; Animals; Antipyrine; Bilirubin; Glucuronates; Glucuronosyltransferase; Humans; Hy | 1974 |