Page last updated: 2024-10-22

antipyrine and Hepatitis C, Chronic

antipyrine has been researched along with Hepatitis C, Chronic in 5 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Hepatitis C, Chronic: INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS.

Research Excerpts

ExcerptRelevanceReference
"We tested whether fibrotic progression in chronic hepatitis C could be predicted by liver tests, antipyrine clearance, or platelet count."7.72Changes in antipyrine clearance and platelet count, but not conventional liver tests, correlate with fibrotic change in chronic hepatitis C: value for predicting fibrotic progression. ( Byth, K; Coverdale, SA; Crewe, E; Farrell, GC; George, J; Kench, J; Khan, MH; Liddle, C; Lin, R; Samarasinghe, DA, 2003)
"We tested whether fibrotic progression in chronic hepatitis C could be predicted by liver tests, antipyrine clearance, or platelet count."3.72Changes in antipyrine clearance and platelet count, but not conventional liver tests, correlate with fibrotic change in chronic hepatitis C: value for predicting fibrotic progression. ( Byth, K; Coverdale, SA; Crewe, E; Farrell, GC; George, J; Kench, J; Khan, MH; Liddle, C; Lin, R; Samarasinghe, DA, 2003)
" The object of the present study was to investigate whether liver metabolic function assessed by antipyrine clearance is related to other disease characteristics influencing response to therapy in chronic hepatitis C."3.71Impairment of metabolic function in chronic hepatitis C is related to factors associated with resistance to therapy. ( Almar, M; Díaz-Golpe, V; García-Fernández, A; González-Gallego, J; Jorquera, F; Olcóz, JL, 2001)
" The pharmacokinetic variables for antipyrine were determined using the two concentration time points selected."2.73Antipyrine clearance in comparison to conventional liver function tests in hepatitis C virus patients. ( Abdel-Kader, R; Botros, S; Hassanein, M; Mahmoud, M; Saleh, S, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gichev, IuP1
Gichev, IuIu1
Grek, OR1
Tolokonskaia, NP1
Chernousova, NIa1
Tomilenko, TG1
Makkosland, K1
Coverdale, SA1
Samarasinghe, DA1
Lin, R1
Kench, J1
Byth, K1
Khan, MH1
Crewe, E1
Liddle, C1
George, J1
Farrell, GC1
Schneider, AR1
Teuber, G1
Paul, K1
Nikodem, A1
Duesterhoeft, M1
Caspary, WF1
Stein, J1
Mahmoud, M1
Abdel-Kader, R1
Hassanein, M1
Saleh, S1
Botros, S1
Jorquera, F1
Almar, M1
Díaz-Golpe, V1
Olcóz, JL1
García-Fernández, A1
González-Gallego, J1

Trials

3 trials available for antipyrine and Hepatitis C, Chronic

ArticleYear
[Experience of biologically active supplements to food containing indoles and isothiocyanates in patients with chronic viral hepatitis].
    Voprosy pitaniia, 2002, Volume: 71, Issue:4

    Topics: Adolescent; Adult; Alanine Transaminase; Antipyrine; Aspartate Aminotransferases; Bilirubin; Case-Co

2002
Patient age is a strong independent predictor of 13C-aminopyrine breath test results: a comparative study with histology, duplex-Doppler and a laboratory index in patients with chronic hepatitis C virus infection.
    Clinical and experimental pharmacology & physiology, 2006, Volume: 33, Issue:4

    Topics: Adult; Aged; Aging; Antipyrine; Aspartate Aminotransferases; Breath Tests; Female; Hepatitis C, Chro

2006
Antipyrine clearance in comparison to conventional liver function tests in hepatitis C virus patients.
    European journal of pharmacology, 2007, Aug-27, Volume: 569, Issue:3

    Topics: Alanine Transaminase; Antipyrine; Aspartate Aminotransferases; Chromatography, High Pressure Liquid;

2007

Other Studies

2 other studies available for antipyrine and Hepatitis C, Chronic

ArticleYear
Changes in antipyrine clearance and platelet count, but not conventional liver tests, correlate with fibrotic change in chronic hepatitis C: value for predicting fibrotic progression.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Antiviral Agents; Biopsy; Disease

2003
Impairment of metabolic function in chronic hepatitis C is related to factors associated with resistance to therapy.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:8

    Topics: Adult; Alanine Transaminase; Antipyrine; Antiviral Agents; Chi-Square Distribution; Drug Resistance,

2001