antipyrine has been researched along with Hepatitis B Virus Infection in 7 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was performed to establish whether sequential determinations of antipyrine clearance, using a simplified two-point test, are sensitive and specific indicators of changes in chronic hepatitis B disease activity." | 9.06 | Serial antipyrine clearance studies detect altered hepatic metabolic function during spontaneous and interferon-induced changes in chronic hepatitis B disease activity. ( Farrell, GC; Williams, SJ, 1989) |
| "To determine whether natural human interferon administered under the usual therapeutic dosing scheme would inhibit the hepatic drug metabolism, we performed an antipyrine test in eight patients with chronic B or non-A, non-B hepatitis before and after a subchronic interferon therapy (6 megaunits/day for 17 +/- 4 days, mean +/- SD)." | 7.68 | Effects of subchronic treatment with natural human interferons on antipyrine clearance and liver function in patients with chronic hepatitis. ( Echizen, H; Ishizaki, T; Oda, T; Ohta, Y; Shirataki, H; Tsukamoto, K; Umeda, N, 1990) |
| "The present study was performed to establish whether sequential determinations of antipyrine clearance, using a simplified two-point test, are sensitive and specific indicators of changes in chronic hepatitis B disease activity." | 5.06 | Serial antipyrine clearance studies detect altered hepatic metabolic function during spontaneous and interferon-induced changes in chronic hepatitis B disease activity. ( Farrell, GC; Williams, SJ, 1989) |
| "To determine whether natural human interferon administered under the usual therapeutic dosing scheme would inhibit the hepatic drug metabolism, we performed an antipyrine test in eight patients with chronic B or non-A, non-B hepatitis before and after a subchronic interferon therapy (6 megaunits/day for 17 +/- 4 days, mean +/- SD)." | 3.68 | Effects of subchronic treatment with natural human interferons on antipyrine clearance and liver function in patients with chronic hepatitis. ( Echizen, H; Ishizaki, T; Oda, T; Ohta, Y; Shirataki, H; Tsukamoto, K; Umeda, N, 1990) |
| "Antipyrine clearance was measured before and 1 day after administration of a single intramuscular dose of recombinant human leukocyte alpha A interferon." | 1.27 | Inhibition of antipyrine metabolism by interferon. ( Farrell, GC; Williams, SJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Habior, A | 1 |
| Bauer, LA | 1 |
| O'Sullivan, T | 1 |
| Reiss, WG | 1 |
| Horn, JR | 1 |
| Opheim, K | 1 |
| Strandness, DE | 1 |
| Carithers, RL | 1 |
| Echizen, H | 1 |
| Ohta, Y | 1 |
| Shirataki, H | 1 |
| Tsukamoto, K | 1 |
| Umeda, N | 1 |
| Oda, T | 1 |
| Ishizaki, T | 1 |
| Tsyrkunov, VM | 1 |
| Bushma, MI | 1 |
| Garelik, PV | 1 |
| Novitskiĭ, GK | 1 |
| Zavodnik, LB | 1 |
| Williams, SJ | 2 |
| Farrell, GC | 2 |
| Musabaev, EI | 1 |
| Krakovskiĭ, ME | 1 |
| Ashirmetov, AKh | 1 |
1 trial available for antipyrine and Hepatitis B Virus Infection
| Article | Year |
|---|---|
Serial antipyrine clearance studies detect altered hepatic metabolic function during spontaneous and interferon-induced changes in chronic hepatitis B disease activity.
Topics: Adult; Alanine Transaminase; Antipyrine; Chronic Disease; Female; Hepatitis B; Hepatitis B e Antigen | 1989 |
6 other studies available for antipyrine and Hepatitis B Virus Infection
| Article | Year |
|---|---|
[Endogenous bile acids in the blood as a functional test in chronic liver diseases. I. Comparison with the antipyrine elimination test].
Topics: Adult; Aged; Antipyrine; Bile Acids and Salts; Chronic Disease; Female; Hepatitis B; Hepatitis, Chro | 1982 |
Liver blood flow, antipyrine clearance, and antipyrine metabolite formation clearance in patients with chronic active hepatitis and alcoholic cirrhosis.
Topics: Adult; Antipyrine; Female; Half-Life; Hepatitis B; Hepatitis C; Hepatitis, Chronic; Humans; Liver Ci | 1994 |
Effects of subchronic treatment with natural human interferons on antipyrine clearance and liver function in patients with chronic hepatitis.
Topics: Adult; Antipyrine; Chromatography, High Pressure Liquid; Female; Fever; Half-Life; Hepatitis B; Hepa | 1990 |
[Pharmacokinetics of antipyrine in viral and alcoholic lesions of the liver].
Topics: Adult; Antipyrine; Biotransformation; Hepatitis B; Humans; Liver; Liver Diseases, Alcoholic; Liver F | 1989 |
[The mono-oxygenase enzyme system of the liver in patients with viral hepatitis A and B].
Topics: Adult; Antipyrine; Clinical Enzyme Tests; Convalescence; Diagnosis, Differential; Half-Life; Hepatit | 1987 |
Inhibition of antipyrine metabolism by interferon.
Topics: Adult; Antipyrine; Female; Hepatitis B; Hepatitis, Chronic; Humans; Interferon Type I; Liver; Longit | 1986 |