Page last updated: 2024-10-22

antipyrine and Hemorrhagic Shock

antipyrine has been researched along with Hemorrhagic Shock in 8 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Research Excerpts

ExcerptRelevanceReference
"Our aim in this study was to find out whether edaravone (3-methyl-1-phenyl-pyrazolin-5-one, MCI-186), a novel free radical scavenger, improved the survival rate in a rat hemorrhagic shock (HS) model."7.74Edaravone improves the survival of rats subjected to hemorrhagic shock without resuscitation. ( Akabori, H; Endo, Y; Mori, T; Shimizu, T; Tani, T; Tsuchihashi, H; Uji, Y; Yamamoto, H, 2008)
"To investigate the effects of edaravone, a novel free radical scavenger, on bacterial translocation induced by hemorrhagic shock."7.73A free radical scavenger, edaravone (MCI-186), diminishes intestinal neutrophil lipid peroxidation and bacterial translocation in a rat hemorrhagic shock model. ( Endo, Y; Fujimiya, M; Hanasawa, K; Mori, T; Shimizu, T; Tabata, T; Tani, T; Yamamoto, H, 2005)
"Our aim in this study was to find out whether edaravone (3-methyl-1-phenyl-pyrazolin-5-one, MCI-186), a novel free radical scavenger, improved the survival rate in a rat hemorrhagic shock (HS) model."3.74Edaravone improves the survival of rats subjected to hemorrhagic shock without resuscitation. ( Akabori, H; Endo, Y; Mori, T; Shimizu, T; Tani, T; Tsuchihashi, H; Uji, Y; Yamamoto, H, 2008)
"To investigate the effects of edaravone, a novel free radical scavenger, on bacterial translocation induced by hemorrhagic shock."3.73A free radical scavenger, edaravone (MCI-186), diminishes intestinal neutrophil lipid peroxidation and bacterial translocation in a rat hemorrhagic shock model. ( Endo, Y; Fujimiya, M; Hanasawa, K; Mori, T; Shimizu, T; Tabata, T; Tani, T; Yamamoto, H, 2005)
"Of the animal models of human hemorrhagic shock, the volume-controlled hemorrhage model appears to come closer to the clinical situation than the commonly used pressure-controlled model, since the volume-controlled model allows regulatory adjustment of blood pressure."1.29Regional heterogeneity of cerebral blood flow response to graded volume-controlled hemorrhage. ( Albrecht, DM; Kuschinsky, W; Riedel, M; van Ackern, K; Waschke, KF, 1996)
"For antipyrine, clearance was decreased by 30% after shock and resuscitation (p = ."1.28Effect of experimental hemorrhagic shock on hepatic drug elimination. ( DiPiro, JT; Gaines, MG; Hooker, KD; Sherman, JC; Wynn, JJ, 1992)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's5 (62.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Uji, Y1
Yamamoto, H2
Mori, T2
Akabori, H1
Tsuchihashi, H1
Shimizu, T2
Endo, Y2
Tani, T2
Waschke, KF2
Riedel, M2
Lenz, C1
Albrecht, DM2
van Ackern, K2
Kuschinsky, W2
Tabata, T1
Hanasawa, K1
Fujimiya, M1
Foëx, BA1
Thorburn, K1
DiPiro, JT1
Hooker, KD1
Sherman, JC1
Gaines, MG1
Wynn, JJ1
Dahlberg, JB1
Lewis, DH1

Other Studies

8 other studies available for antipyrine and Hemorrhagic Shock

ArticleYear
Edaravone improves the survival of rats subjected to hemorrhagic shock without resuscitation.
    Surgery today, 2008, Volume: 38, Issue:5

    Topics: Animals; Antipyrine; Disease Models, Animal; Edaravone; Free Radical Scavengers; Male; Rats; Rats, S

2008
Regional heterogeneity of cerebral blood flow response to graded pressure-controlled hemorrhage.
    The Journal of trauma, 2004, Volume: 56, Issue:3

    Topics: Animals; Antipyrine; Autoradiography; Blood Pressure; Brain; Brain Mapping; Carbon Radioisotopes; Ho

2004
A free radical scavenger, edaravone (MCI-186), diminishes intestinal neutrophil lipid peroxidation and bacterial translocation in a rat hemorrhagic shock model.
    Critical care medicine, 2005, Volume: 33, Issue:5

    Topics: Animals; Antipyrine; Bacterial Translocation; Edaravone; Free Radical Scavengers; Ileum; Lipid Perox

2005
Bacterial translocation in hemorrhagic shock: Are we any wiser?
    Critical care medicine, 2005, Volume: 33, Issue:5

    Topics: Animals; Antipyrine; Bacterial Translocation; Edaravone; Free Radical Scavengers; Lipid Peroxidation

2005
Bacterial translocation and intestinal neutrophil lipid peroxidation in a hemorrhagic shock model--Rat race or rat trap?
    Critical care medicine, 2005, Volume: 33, Issue:5

    Topics: Animals; Antipyrine; Bacterial Translocation; Edaravone; Free Radical Scavengers; Humans; Lipid Pero

2005
Regional heterogeneity of cerebral blood flow response to graded volume-controlled hemorrhage.
    Intensive care medicine, 1996, Volume: 22, Issue:10

    Topics: Animals; Antipyrine; Autoradiography; Blood Flow Velocity; Blood Pressure; Blood Volume; Carbon Radi

1996
Effect of experimental hemorrhagic shock on hepatic drug elimination.
    Critical care medicine, 1992, Volume: 20, Issue:6

    Topics: Animals; Antipyrine; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Half-Life

1992
Effect of hemorrhagic shock on capillary transport in dog skeletal muscle.
    Bibliotheca anatomica, 1973, Volume: 12

    Topics: Animals; Antipyrine; Biological Transport; Capillaries; Chlorides; Chromium Radioisotopes; Dogs; Ede

1973