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antipyrine and Gastroduodenal Ulcer

antipyrine has been researched along with Gastroduodenal Ulcer in 7 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Research Excerpts

ExcerptRelevanceReference
"Metabolism of antipyrine was studied in 12 patients with gastric carcinoma and 5 control subjects with peptic ulcer matched for sex, body weight, height, and smoking history."3.66Microsomal enzymes in patients with gastric carcinoma as determined by plasma half-life of antipyrine. ( Higuchi, T; Nakamura, T; Uchino, H, 1978)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Staiger, C1
Simon, B1
Walter, E1
Kather, H1
Sebestyén, G1
Gergely, V1
Virág, S1
Mészáros, Z1
Higuchi, T1
Nakamura, T1
Uchino, H1
Gachályi, B1
Vas, A1
Csillag, K1
Nagy, B1
Kocsis, F1
Káldor, A1
Adamska-Dyniewska, I1
Tkaczewski, W1
Jabłkowski, M1
Chojnacki, J1
Kettner, W1
Schröter, U1
Banditt, P1
Walther, H1
Welch, RM1
Harrison, YE1
Burns, JJ1

Trials

1 trial available for antipyrine and Gastroduodenal Ulcer

ArticleYear
[The acetylator phenotype affects the antipyrine metabolism inhibiting action of cimetidine].
    Orvosi hetilap, 1986, Jun-22, Volume: 127, Issue:25

    Topics: Acetylation; Antipyrine; Cimetidine; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male

1986

Other Studies

6 other studies available for antipyrine and Gastroduodenal Ulcer

ArticleYear
Influence of ranitidine on antipyrine pharmacokinetics in healthy volunteers.
    Digestive diseases and sciences, 1980, Volume: 25, Issue:11

    Topics: Antipyrine; Drug Interactions; Furans; Humans; Peptic Ulcer; Ranitidine

1980
Investigation of the interaction between Probon and indomethacin in rats.
    Journal of applied toxicology : JAT, 1983, Volume: 3, Issue:1

    Topics: Animals; Antipyrine; Drug Interactions; Drug Therapy, Combination; Female; Indomethacin; Male; Pepti

1983
Microsomal enzymes in patients with gastric carcinoma as determined by plasma half-life of antipyrine.
    Gan, 1978, Volume: 69, Issue:6

    Topics: Antipyrine; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Microsomes, Liver; Peptic Ulc

1978
[Effect of combined therapy with cimetidine and (+)-cyanidanol-3 on the hepatic clearance of antipyrine].
    Polskie Archiwum Medycyny Wewnetrznej, 1986, Volume: 75, Issue:3

    Topics: Adolescent; Adult; Antipyrine; Catechin; Cimetidine; Drug Therapy, Combination; Female; Humans; Live

1986
[Effect of histamine H2 receptor blockers on hepatic elimination of drugs].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1985, Feb-15, Volume: 40, Issue:4

    Topics: Adult; Antipyrine; Cimetidine; Half-Life; Humans; Liver; Male; Metabolic Clearance Rate; Peptic Ulce

1985
Implications of enzyme induction in drug toxicity studies.
    Toxicology and applied pharmacology, 1967, Volume: 10, Issue:2

    Topics: Animals; Antipyrine; Diphenhydramine; Dogs; Enzyme Induction; Female; Haplorhini; Liver; Male; Micro

1967