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antipyrine and Experimental Neoplasms

antipyrine has been researched along with Experimental Neoplasms in 10 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Research Excerpts

ExcerptRelevanceReference
" Parallel studies were performed to measure relative changes in tumor blood perfusion using [14C]iodo-antipyrine and changes in % tumor necrosis using Chalkley's method."3.67Phosphorus-31 magnetic resonance spectroscopy and blood perfusion of the RIF-1 tumor following X-irradiation. ( Bhujwalla, ZM; Griffiths, JR; Maxwell, RJ; Tozer, GM, 1989)
"Antipyrine oxidation was increased in the cancerous state but the urinary metabolic profiles were similar in rats with cancer and in controls."1.28Drug metabolism in rats with cancer induced by N-nitrosodiethylamine and phenobarbital. ( Aitio, ML; Arvela, P; Bartsch, H; Béréziat, JC; Hietanen, E, 1992)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's2 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rogers, W2
Edlich, RF2
Lewis, DV1
Aust, JB2
Crouzette, J1
Fournier, PE1
Ripault, J1
Johansson, SL1
Kjartansson, I1
Villeneuve, JP1
Gerber, JG1
Branch, RA1
Shand, DG1
Wilson, JT1
Aitio, ML1
Hietanen, E1
Béréziat, JC1
Arvela, P1
Bartsch, H1
Mathias, CJ1
Welch, MJ1
Perry, DJ1
McGuire, AH1
Zhu, X1
Connett, JM1
Green, MA1
Tozer, GM1
Bhujwalla, ZM1
Griffiths, JR1
Maxwell, RJ1
Breslow, DS1
Edwards, EI1
Newburg, NR1

Other Studies

10 other studies available for antipyrine and Experimental Neoplasms

ArticleYear
Tumor blood flow: I. Blood flow in transplantable tumors during growth.
    The Surgical clinics of North America, 1967, Volume: 47, Issue:6

    Topics: Animals; Antipyrine; Chromium Isotopes; Coloring Agents; Cricetinae; Female; Hemodynamics; Iodine Is

1967
[Comparison of the effects of absorption of aminophenazone or propyphenazone combined with sodium nitrite on the incidence and early appearance of tumors in the rat].
    Annales de la nutrition et de l'alimentation, 1980, Volume: 34, Issue:5-6

    Topics: Aminopyrine; Animals; Antipyrine; Carcinogens; Drug Interactions; Female; Male; Neoplasms, Experimen

1980
Carcinogenicity of analgesics: long-term treatment of Sprague-Dawley rats with phenacetin, phenazone, caffeine and paracetamol (acetamidophen).
    International journal of cancer, 1981, Volume: 27, Issue:4

    Topics: Acetaminophen; Adenocarcinoma; Analgesics; Animals; Antipyrine; Caffeine; Carcinogens; Carcinoma, Sq

1981
Tumour circulation. An experimental study in the rat with a comparison of different methods for estimation of tumour blood flow.
    Acta chirurgica Scandinavica. Supplementum, 1976, Volume: 471

    Topics: Angiography; Animals; Antipyrine; Carcinoma, Hepatocellular; Iodine Radioisotopes; Liver Neoplasms;

1976
Drug metabolism in rats bearing a pituitary mammotropic tumor.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 209, Issue:1

    Topics: Aminopyrine; Animals; Antipyrine; Cardiac Output; Half-Life; Liver; Male; Mammary Glands, Animal; Ne

1979
Drug metabolism in rats with cancer induced by N-nitrosodiethylamine and phenobarbital.
    Pharmacology & toxicology, 1992, Volume: 70, Issue:6 Pt 1

    Topics: Animals; Antipyrine; Debrisoquin; Diethylnitrosamine; Liver; Male; Microsomes, Liver; Neoplasms, Exp

1992
Investigation of copper-PTSM as a PET tracer for tumor blood flow.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1991, Volume: 18, Issue:7

    Topics: Animals; Antipyrine; Brain; Colonic Neoplasms; Copper; Coronary Vessels; Cricetinae; Humans; Kidney;

1991
Phosphorus-31 magnetic resonance spectroscopy and blood perfusion of the RIF-1 tumor following X-irradiation.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antipyrine; Energy Metabolism; Magnetic Resonance Spectroscopy; Mal

1989
Divinyl ether-maleic anhydride (pyran) copolymer used to demonstrate the effect of molecular weight on biological activity.
    Nature, 1973, Nov-16, Volume: 246, Issue:5429

    Topics: Alanine Transaminase; Aminopyrine; Animals; Antineoplastic Agents; Antipyrine; Carcinoma, Ehrlich Tu

1973
Tumor blood flow. II. Distribution of blood flow in experimental tumors.
    Angiology, 1969, Volume: 20, Issue:7

    Topics: Animals; Antipyrine; Chromium Isotopes; Coloring Agents; Cricetinae; Iodine Isotopes; Liver Circulat

1969