antipyrine has been researched along with Edema in 21 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effects of edaravone, a free radical scavenger, on peripheral nerve ischemia-reperfusion injury caused by ligation of vessels supplying the sciatic and tibial nerves in rats." | 7.75 | Effect of the free radical scavenger edaravone on peripheral nerve ischemia-reperfusion injury. ( Iida, H; Nagasaka, T; Shindo, K; Shiozawa, Z, 2009) |
| "Compared to vehicle group, IR significantly decreased the PO(2) level and increased the wet-to-dry ratio, proteins in bronchoalveolar lavage (BAL), and myeloperoxidase (MPO) activity in the control group, while edaravone treatment maintained the PO(2) similar to the vehicle group and significantly reduced edema formation and neutrophil extravasation." | 7.73 | MCI-186 (edaravone), a free radical scavenger, attenuates ischemia-reperfusion injury and activation of phospholipase A(2) in an isolated rat lung model after 18 h of cold preservation. ( Akamatsu, H; Reyes, YA; Shimoyama, T; Sunamori, M, 2006) |
| " The aims of this paper are to synthesize the mutual prodrugs of selected NSAIDs (Ketorolac, niflumic acid, tolfenamic acid) with propyphenazone, a study on their several physicochemical characters, hydrolysis kinetics, antiinflammatory, analgesic activity and ulcerogenicity." | 3.85 | Synthesis and Biological Evaluation of Mutual Prodrugs of Carboxylic Group Containing Some Non-Steroidal Anti-Inflammatory Drugs and Propyphenazone. ( Jain, S; Paliwal, M, 2017) |
| "We investigated the effects of edaravone, a free radical scavenger, on peripheral nerve ischemia-reperfusion injury caused by ligation of vessels supplying the sciatic and tibial nerves in rats." | 3.75 | Effect of the free radical scavenger edaravone on peripheral nerve ischemia-reperfusion injury. ( Iida, H; Nagasaka, T; Shindo, K; Shiozawa, Z, 2009) |
| "Compared to vehicle group, IR significantly decreased the PO(2) level and increased the wet-to-dry ratio, proteins in bronchoalveolar lavage (BAL), and myeloperoxidase (MPO) activity in the control group, while edaravone treatment maintained the PO(2) similar to the vehicle group and significantly reduced edema formation and neutrophil extravasation." | 3.73 | MCI-186 (edaravone), a free radical scavenger, attenuates ischemia-reperfusion injury and activation of phospholipase A(2) in an isolated rat lung model after 18 h of cold preservation. ( Akamatsu, H; Reyes, YA; Shimoyama, T; Sunamori, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (61.90) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Sanea, MM | 1 |
| Hamdi, A | 1 |
| Brogi, S | 1 |
| S Tawfik, S | 1 |
| Othman, DIA | 1 |
| Elshal, M | 1 |
| Ur Rahman, H | 1 |
| Parambi, DGT | 1 |
| M Elbargisy, R | 1 |
| Selim, S | 1 |
| Mostafa, EM | 1 |
| Mohamed, AAB | 1 |
| Hu, H | 1 |
| Sun, Xo | 1 |
| Tian, F | 1 |
| Zhang, H | 1 |
| Liu, Q | 1 |
| Tan, W | 1 |
| Paliwal, M | 1 |
| Jain, S | 1 |
| Iida, H | 1 |
| Nagasaka, T | 1 |
| Shindo, K | 1 |
| Shiozawa, Z | 1 |
| WAGNER-JAUREGG, T | 1 |
| JAHN, U | 1 |
| BUECH, O | 1 |
| FALLER, IL | 1 |
| PETTY, D | 1 |
| LAST, JH | 1 |
| PASCALE, LR | 1 |
| BOND, EE | 1 |
| HURST, WW | 1 |
| SCHEMM, FR | 1 |
| VOGEL, WC | 1 |
| Watanabe, T | 1 |
| Tanaka, M | 1 |
| Watanabe, K | 1 |
| Takamatsu, Y | 1 |
| Tobe, A | 1 |
| Reyes, YA | 1 |
| Shimoyama, T | 1 |
| Akamatsu, H | 1 |
| Sunamori, M | 1 |
| Aonuma, S | 2 |
| Kohama, Y | 2 |
| Komiyama, Y | 1 |
| Fujimoto, S | 1 |
| Lucaská, B | 1 |
| Sokolík, J | 1 |
| Tumová, I | 1 |
| Svec, P | 1 |
| Krätsmár-Smogrović, J | 1 |
| Skjelbred, P | 1 |
| Løkken, P | 1 |
| Sparatore, F | 1 |
| Pirisino, G | 1 |
| Alamanni, MC | 1 |
| Manca-Dimich, P | 1 |
| Satta, M | 1 |
| Chen, IJ | 1 |
| Yashiki, S | 1 |
| Egawa, H | 1 |
| Sasaki, K | 2 |
| Ishikawa, M | 1 |
| Takayanagi, Y | 1 |
| Urbach, J | 1 |
| Boadi, W | 1 |
| Brandes, JM | 1 |
| Kerner, H | 1 |
| Yannai, S | 1 |
| Chiti, W | 1 |
| Ciocia, G | 1 |
| Brogden, RN | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Nardi, D | 2 |
| Massarani, E | 2 |
| Magistretti, MJ | 2 |
| Samter, M | 1 |
| Beers, RF | 1 |
1 review available for antipyrine and Edema
| Article | Year |
|---|---|
[Research and development of the free radical scavenger edaravone as a neuroprotectant].
Topics: Animals; Antipyrine; Brain Ischemia; Clinical Trials as Topic; Drug Design; Edaravone; Edema; Free R | 2004 |
2 trials available for antipyrine and Edema
| Article | Year |
|---|---|
Phenazone versus placebo: effects on post-operative course.
Topics: Adult; Antipyrine; Body Temperature; Double-Blind Method; Edema; Female; Humans; Inflammation; Male; | 1980 |
Ketoprofen: a preliminary report of its pharmacological activity and therapeutic efficacy in rheumatic disorders.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyrine; Arthritis, Rheumatoid; Benzophenones; Bra | 1974 |
18 other studies available for antipyrine and Edema
| Article | Year |
|---|---|
Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Celecoxib; Cyclooxyge | 2023 |
Neuroprotective Effects of Isosteviol Sodium Injection on Acute Focal Cerebral Ischemia in Rats.
Topics: Animals; Antipyrine; Brain; Dose-Response Relationship, Drug; Edaravone; Edema; Immunohistochemistry | 2016 |
Synthesis and Biological Evaluation of Mutual Prodrugs of Carboxylic Group Containing Some Non-Steroidal Anti-Inflammatory Drugs and Propyphenazone.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Carboxylic Acids; Dose-Res | 2017 |
Effect of the free radical scavenger edaravone on peripheral nerve ischemia-reperfusion injury.
Topics: Animals; Antipyrine; Behavior, Animal; Edaravone; Edema; Electrophysiology; Free Radical Scavengers; | 2009 |
[The antiphlogistic testing of known antirheumatics on kaolin-induced rat paw edema].
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Antipyrine; Azoles; Edema; | 1962 |
A comparison of the deuterium oxide and antipyrine dilution methods for measuring total body water in normal and hydropic human subjects.
Topics: Analgesics; Antipyrine; Body Fluids; Body Water; Deuterium; Deuterium Oxide; Edema; Humans; Indicato | 1955 |
Simultaneous determination of total body water by antipyrine and deuterium oxide; evaluation of the methods on edematous subjects.
Topics: Antipyrine; Body Fluids; Body Water; Deuterium Oxide; Edema; Humans | 1952 |
MCI-186 (edaravone), a free radical scavenger, attenuates ischemia-reperfusion injury and activation of phospholipase A(2) in an isolated rat lung model after 18 h of cold preservation.
Topics: Animals; Antipyrine; Bronchoalveolar Lavage Fluid; Cold Ischemia; Disease Models, Animal; Edaravone; | 2006 |
Gastric ulcerogenic and biological activities of N-3'a-propyphenazonyl-2-acetoxybenzamide.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; | 1980 |
[Antiphlogistic, antipyretic and toxicological properties of carboxylate-copper compounds].
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Carboxylic A | 1982 |
[Azomethine derivatives with anti-inflammatory activity].
Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents; Antipyrine; Azo Compounds; Benzophenones; Edem | 1978 |
[Effect of ephedrine-isopropylantipyrine on edema and increased vascular permeability (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Antipyrine; Capillary Permeability; Drug Combinations; Edema; Eph | 1976 |
[The depression of hepatic drug-metabolizing enzyme activity in rats with carrageenan-induced inflammation. II. The effect on the status of plasma antipyrine concentration in rats].
Topics: Aminopyrine N-Demethylase; Animals; Antipyrine; Carrageenan; Cytochrome P-450 Enzyme System; Edema; | 1992 |
Effect of inorganic mercury on in vitro placental nutrient transfer and oxygen consumption.
Topics: 3-O-Methylglucose; Amino Acids; Aminoisobutyric Acids; Antipyrine; Biological Transport; Edema; Fema | 1992 |
Pharmacological research on N-methyl-N-antipyrylnicotinamide: synergic and antagonistic effects as to aminopyrine.
Topics: Aminopyrine; Analgesics; Animals; Antipyrine; Chemical Phenomena; Chemistry; Drug Synergism; Edema; | 1972 |
4-phenylglioxylidenamino-antipyrine with antiphlogistic and analgesic activity.
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Antipyrine; Antiviral Agents; Chick Embr | 1969 |
Concerning the nature of intolerance to aspirin.
Topics: Aminopyrine; Antipyrine; Aspirin; Asthma; Chemoreceptor Cells; Drug Hypersensitivity; Edema; Histami | 1967 |
4(beta-benzoylvinyl)-antipyrine derivatives after antiphlogistic and analgesic activity.
Topics: Acetophenones; Aminopyrine; Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; An | 1969 |