antipyrine has been researched along with Diathesis in 6 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Experiments in rats with different sensitivity to hypobaric hypoxia established bimodal distribution of antipyrine and isoniazide half-lives." | 7.68 | [The effect of acute hypoxia on antipyrine and isoniazid pharmacokinetics in rats with different resistances to oxygen deficiency]. ( Grek, OR; Kolpakov, MA; Sharapov, VI, 1993) |
| " The extent of cerebral ischemia during BCO was evaluated with [14C]iodoantipyrine autoradiography." | 3.69 | Resistance to cerebral ischemia in developing gerbils. ( Arai, H; Kusumoto, M; Mori, K; Sato, K, 1995) |
| "Experiments in rats with different sensitivity to hypobaric hypoxia established bimodal distribution of antipyrine and isoniazide half-lives." | 3.68 | [The effect of acute hypoxia on antipyrine and isoniazid pharmacokinetics in rats with different resistances to oxygen deficiency]. ( Grek, OR; Kolpakov, MA; Sharapov, VI, 1993) |
| " It should be taken into account when dosing drugs which are metabolized as markers of the liver metabolic efficiency like phenazone and sulphadimidine." | 2.68 | [Evaluation of phenazone oxidation and sulfadimidine acetylation in patients with hematologic neoplasms]. ( Kotlarek-Haus, S; Milejski, P; Orzechowska-Juzwenko, K; Urbaniak-Kujda, D; Usnarska-Zubkiewicz, L; Wiela-Hojeńska, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kusumoto, M | 1 |
| Arai, H | 1 |
| Mori, K | 1 |
| Sato, K | 1 |
| Sharapov, VI | 1 |
| Kolpakov, MA | 1 |
| Grek, OR | 1 |
| Orzechowska-Juzwenko, K | 2 |
| Wiela-Hojeńska, A | 2 |
| Milejski, P | 2 |
| Cieślińska, A | 1 |
| Hudziec, P | 1 |
| Adamska, M | 1 |
| Usnarska-Zubkiewicz, L | 1 |
| Urbaniak-Kujda, D | 1 |
| Kotlarek-Haus, S | 1 |
| Radzikowska, E | 1 |
| Gazdzik, W | 1 |
| Rowińska-Zakrzewska, E | 1 |
| Aitio, A | 1 |
| Aitio, ML | 1 |
| Camus, AM | 1 |
| Cardis, E | 1 |
| Bartsch, H | 1 |
2 trials available for antipyrine and Diathesis
| Article | Year |
|---|---|
[Biotransformation of phenazone and sulfadimidine as markers of liver metabolism of drug and xenobiotic oxidation and acetylation in women with breast cancer].
Topics: Acetylation; Adult; Aged; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine | 1997 |
[Evaluation of phenazone oxidation and sulfadimidine acetylation in patients with hematologic neoplasms].
Topics: Acetylation; Adolescent; Adult; Aged; Antipyrine; Disease Susceptibility; Female; Hodgkin Disease; H | 1997 |
4 other studies available for antipyrine and Diathesis
| Article | Year |
|---|---|
Resistance to cerebral ischemia in developing gerbils.
Topics: Aging; Animals; Antipyrine; Body Temperature; Brain; Brain Ischemia; Cell Death; Cerebrovascular Cir | 1995 |
[The effect of acute hypoxia on antipyrine and isoniazid pharmacokinetics in rats with different resistances to oxygen deficiency].
Topics: Acute Disease; Animals; Antipyrine; Atmosphere Exposure Chambers; Disease Susceptibility; Half-Life; | 1993 |
Antipyrine metabolism in lung cancer patients and their relatives.
Topics: Adult; Aged; Antipyrine; Aryl Hydrocarbon Hydroxylases; Biotransformation; Disease Susceptibility; E | 1997 |
Cytochrome P-450 isozyme pattern is related to individual susceptibility to diethylnitrosamine-induced liver cancer in rats.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carcinoma, Hepato | 1991 |