antipyrine has been researched along with Diabetes Mellitus in 8 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomized, double-blind, placebo-controlled study was performed to prospectively evaluate the effects of edaravone on acute diabetic stroke patients admitted to our hospital within 24 h of stroke onset." | 9.22 | Edaravone offers neuroprotection for acute diabetic stroke patients. ( Chen, X; Zheng, J, 2016) |
| "Among patients treated with edaravone alone and edaravone + tPA, the mean reduction in the National Institutes of Health Stroke Scale from baseline to 3 months after the onset was 2." | 7.88 | Outcome of Acute Ischemic Stroke after the Treatment with Edaravone and 0.6 Mg/Kg Alteplase in Japanese Patients with Diabetes. ( Awano, H; Matsuda, H; Tanahashi, N; Yamaguchi, T, 2018) |
| "A randomized, double-blind, placebo-controlled study was performed to prospectively evaluate the effects of edaravone on acute diabetic stroke patients admitted to our hospital within 24 h of stroke onset." | 5.22 | Edaravone offers neuroprotection for acute diabetic stroke patients. ( Chen, X; Zheng, J, 2016) |
| "Among patients treated with edaravone alone and edaravone + tPA, the mean reduction in the National Institutes of Health Stroke Scale from baseline to 3 months after the onset was 2." | 3.88 | Outcome of Acute Ischemic Stroke after the Treatment with Edaravone and 0.6 Mg/Kg Alteplase in Japanese Patients with Diabetes. ( Awano, H; Matsuda, H; Tanahashi, N; Yamaguchi, T, 2018) |
| "The antipyrine test was selected as an in vivo index, since its kinetics indirectly reflect the metabolically active liver mass." | 1.26 | The evaluation of the drug-metabolizing capacity in patients with diabetes mellitus. ( Pelkonen, RO; Salmela, PI; Sotaniemi, EA, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanahashi, N | 1 |
| Yamaguchi, T | 1 |
| Awano, H | 1 |
| Matsuda, H | 1 |
| Zheng, J | 1 |
| Chen, X | 1 |
| Munck, O | 1 |
| Andersen, AM | 1 |
| Binder, C | 1 |
| Sotaniemi, EA | 2 |
| Arranto, AJ | 1 |
| Sutinen, S | 2 |
| Stengård, JH | 1 |
| Geller, LI | 1 |
| Griaznova, MV | 1 |
| Bulgakova, OS | 1 |
| Kozlova, ZP | 1 |
| Salmela, PI | 1 |
| Pelkonen, RO | 1 |
| Daintith, H | 1 |
| Stevenson, IH | 1 |
| O'Malley, K | 1 |
| Narang, AP | 1 |
| Dutta, DV | 1 |
| Khare, AK | 1 |
1 trial available for antipyrine and Diabetes Mellitus
| Article | Year |
|---|---|
Edaravone offers neuroprotection for acute diabetic stroke patients.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Antipyrine; Diabetes Mellitus; Double-Blind Met | 2016 |
7 other studies available for antipyrine and Diabetes Mellitus
| Article | Year |
|---|---|
Outcome of Acute Ischemic Stroke after the Treatment with Edaravone and 0.6 Mg/Kg Alteplase in Japanese Patients with Diabetes.
Topics: Aged; Aged, 80 and over; Antipyrine; Brain Ischemia; Diabetes Mellitus; Disability Evaluation; Disea | 2018 |
Clearance of 4-iodoantipyrine-125-I after subcutaneous injection in various regions.
Topics: Abdomen; Adult; Aged; Antipyrine; Autoradiography; Back; Coloring Agents; Diabetes Mellitus; Female; | 1967 |
Treatment of noninsulin-dependent diabetes mellitus with enzyme inducers.
Topics: Aged; Antipyrine; Blood Glucose; Diabetes Mellitus; Enzyme Induction; Female; Humans; Hypoglycemic A | 1983 |
[Pharmacometabolic capacity of the liver and the effect of pancreozymin in chronic hepatitis, chronic pancreatitis and diabetes mellitus].
Topics: Adult; Antipyrine; Biotransformation; Cholecystokinin; Chronic Disease; Diabetes Mellitus; Hepatitis | 1982 |
The evaluation of the drug-metabolizing capacity in patients with diabetes mellitus.
Topics: Antipyrine; Cytochrome P-450 Enzyme System; Diabetes Complications; Diabetes Mellitus; Fatty Liver; | 1980 |
Influence of diabetes mellitus on drug metabolism in man.
Topics: Antipyrine; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Female; Half-Life; Humans; Insulin; K | 1976 |
Impairment of drug clearance in patients with diabetes mellitus & liver cirrhosis.
Topics: Antipyrine; Diabetes Mellitus; Female; Humans; Kinetics; Liver; Liver Cirrhosis; Male; Metabolic Cle | 1987 |