antipyrine has been researched along with Colorectal Neoplasms in 4 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the functional activity of a liver with solid metastases from primary colorectal cancer, antipyrine metabolism was studied after the drug was administered orally (18 mg/kg body weight) to 55 healthy volunteers, 62 patients with well-compensated cirrhosis, and 42 patients with small (Class A) or massive (Class B) metastatic liver involvement." | 7.68 | Antipyrine metabolism in patients with liver metastases from colorectal cancer. ( Astone, A; Barone, C; Cassano, A; Castellano, R; Coletta, P; Gambassi, G; Grieco, A; Ragazzoni, E, 1992) |
| "To assess the functional activity of a liver with solid metastases from primary colorectal cancer, antipyrine metabolism was studied after the drug was administered orally (18 mg/kg body weight) to 55 healthy volunteers, 62 patients with well-compensated cirrhosis, and 42 patients with small (Class A) or massive (Class B) metastatic liver involvement." | 3.68 | Antipyrine metabolism in patients with liver metastases from colorectal cancer. ( Astone, A; Barone, C; Cassano, A; Castellano, R; Coletta, P; Gambassi, G; Grieco, A; Ragazzoni, E, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Casillas, S | 1 |
| Dietz, DW | 1 |
| Brand, MI | 1 |
| Jones, SC | 1 |
| Vladisavljevic, A | 1 |
| Milsom, JW | 1 |
| Burke, D | 1 |
| Carnochan, P | 1 |
| Glover, C | 1 |
| Allen-Mersh, TG | 1 |
| Grieco, A | 1 |
| Barone, C | 1 |
| Coletta, P | 1 |
| Castellano, R | 1 |
| Ragazzoni, E | 1 |
| Cassano, A | 1 |
| Astone, A | 1 |
| Gambassi, G | 1 |
| Robertz-Vaupel, GM | 1 |
| Lindecken, KD | 1 |
| Edeki, T | 1 |
| Funke, C | 1 |
| Belwon, S | 1 |
| Dengler, HJ | 1 |
4 other studies available for antipyrine and Colorectal Neoplasms
| Article | Year |
|---|---|
Perfusion to colorectal cancer liver metastases is not uniform and depends on tumor location and feeding vessel.
Topics: Adenocarcinoma; Animals; Antipyrine; Autoradiography; Colorectal Neoplasms; Female; Hepatic Artery; | 1997 |
Correlation between tumour blood flow and fluorouracil distribution in a hypovascular liver metastasis model.
Topics: Animals; Antimetabolites, Antineoplastic; Antipyrine; Calibration; Colorectal Neoplasms; Fluorouraci | 2000 |
Antipyrine metabolism in patients with liver metastases from colorectal cancer.
Topics: Adult; Aged; Antipyrine; Colorectal Neoplasms; Female; Humans; Liver Cirrhosis; Liver Function Tests | 1992 |
Disposition of antipyrine in patients with extensive metastatic liver disease.
Topics: Adenocarcinoma; Aged; Antipyrine; Colorectal Neoplasms; Edaravone; Female; Humans; Liver Neoplasms; | 1992 |