antipyrine has been researched along with Cognition Disorders in 6 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with edaravone can prevent development of cognitive impairment after CEA." | 2.71 | Effects of the free radical scavenger, edaravone, on the development of postoperative cognitive impairment in patients undergoing carotid endarterectomy. ( Endo, H; Fukuda, T; Inoue, T; Kobayashi, M; Ogasawara, K; Ogawa, A; Terasaki, K; Yamadate, K; Yoshida, K, 2005) |
| "Treatment with edaravone significantly improved STZ-induced cognitive damage as evaluated in Morris water maze and step-down tests and markedly restored changes in malondialdehyde (MDA), 4-hydroxy-2-nonenal (4-HNE) adducts, hydroxyl radical (OH), hydrogen peroxide (H2O2), total superoxide dismutase (T-SOD), reduced glutathione (GSH), glutathione peroxidase (GPx) and protein carbonyl (PC) levels." | 1.39 | Neuroprotective effects of edaravone on cognitive deficit, oxidative stress and tau hyperphosphorylation induced by intracerebroventricular streptozotocin in rats. ( Chi, L; Yu, G; Zhang, L; Zhang, W; Zhang, Y; Zhou, S; Zhu, J, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, S | 1 |
| Yu, G | 1 |
| Chi, L | 1 |
| Zhu, J | 1 |
| Zhang, W | 1 |
| Zhang, Y | 1 |
| Zhang, L | 1 |
| Chen, Z | 1 |
| Zhang, J | 2 |
| Chen, Q | 1 |
| Guo, J | 1 |
| Zhu, G | 1 |
| Feng, H | 1 |
| Jiao, SS | 1 |
| Yao, XQ | 1 |
| Liu, YH | 1 |
| Wang, QH | 1 |
| Zeng, F | 1 |
| Lu, JJ | 1 |
| Liu, J | 1 |
| Zhu, C | 1 |
| Shen, LL | 1 |
| Liu, CH | 1 |
| Wang, YR | 1 |
| Zeng, GH | 1 |
| Parikh, A | 1 |
| Chen, J | 1 |
| Liang, CR | 1 |
| Xiang, Y | 1 |
| Bu, XL | 1 |
| Deng, J | 1 |
| Li, J | 1 |
| Xu, J | 1 |
| Zeng, YQ | 1 |
| Xu, X | 1 |
| Xu, HW | 1 |
| Zhong, JH | 1 |
| Zhou, HD | 1 |
| Zhou, XF | 1 |
| Wang, YJ | 1 |
| Jiao, L | 1 |
| Li, Z | 1 |
| Liu, H | 1 |
| Chen, Y | 1 |
| Xu, S | 1 |
| Ohta, M | 1 |
| Higashi, Y | 1 |
| Yawata, T | 1 |
| Kitahara, M | 1 |
| Nobumoto, A | 1 |
| Ishida, E | 1 |
| Tsuda, M | 1 |
| Fujimoto, Y | 1 |
| Shimizu, K | 1 |
| Ogasawara, K | 1 |
| Yamadate, K | 1 |
| Kobayashi, M | 1 |
| Endo, H | 1 |
| Fukuda, T | 1 |
| Yoshida, K | 1 |
| Terasaki, K | 1 |
| Inoue, T | 1 |
| Ogawa, A | 1 |
1 trial available for antipyrine and Cognition Disorders
| Article | Year |
|---|---|
Effects of the free radical scavenger, edaravone, on the development of postoperative cognitive impairment in patients undergoing carotid endarterectomy.
Topics: Aged; Antipyrine; Carotid Artery, Internal; Carotid Stenosis; Cerebral Infarction; Cerebrovascular C | 2005 |
5 other studies available for antipyrine and Cognition Disorders
| Article | Year |
|---|---|
Neuroprotective effects of edaravone on cognitive deficit, oxidative stress and tau hyperphosphorylation induced by intracerebroventricular streptozotocin in rats.
Topics: Alzheimer Disease; Animals; Antipyrine; Cognition Disorders; Edaravone; Free Radical Scavengers; Inf | 2013 |
Neuroprotective effects of edaravone after intraventricular hemorrhage in rats.
Topics: Animals; Antipyrine; Brain Edema; Cerebral Hemorrhage; Cognition Disorders; Edaravone; Free Radical | 2014 |
Edaravone alleviates Alzheimer's disease-type pathologies and cognitive deficits.
Topics: Administration, Oral; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Antipyrine; Behavi | 2015 |
Edaravone alleviates delayed neuronal death and long-dated cognitive dysfunction of hippocampus after transient focal ischemia in Wistar rat brains.
Topics: Animals; Antipyrine; Brain Ischemia; Cognition Disorders; Disease Models, Animal; Edaravone; Free Ra | 2011 |
Attenuation of axonal injury and oxidative stress by edaravone protects against cognitive impairments after traumatic brain injury.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antipyrine; Brain Injuries; Cognition; Cognition Disorders; De | 2013 |