antipyrine has been researched along with Chronic Kidney Failure in 13 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pharmacokinetic variable values in elderly subjects did not differ in a clinically significant manner from those in younger subjects." | 1.28 | Pharmacokinetics of misoprostol in the elderly, in patients with renal failure and when coadministered with NSAID or antipyrine, propranolol or diazepam. ( Karim, A; Nicholson, PA; Smith, M, 1990) |
| "Antipyrine was given orally to five patients with Chronic renal failure and nine normal subjects." | 1.26 | Antipyrine kinetics in Nigerian women in chronic renal failure. ( Iyun, AO; Tucker, GT, 1982) |
| "Antipyrine (10 mg/kg) was given orally and assayed in saliva by gas-liquid chromatography." | 1.26 | Salivary antipyrine kinetics in hepatic and renal disease and in patients on anticonvulsant therapy. ( Clarkson, AR; Frewin, DB; Harman, AW; Penhall, RK; Phillips, PJ; Priestly, BG, 1977) |
| "1." | 1.25 | The plasma half-life of antipyrine in chromic uraemic and normal subjects. ( Harber, MJ; Maddocks, JL; Wake, CJ, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (69.23) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iyun, AO | 1 |
| Tucker, GT | 1 |
| Pollack, GM | 1 |
| Shen, DD | 1 |
| Lanchote, VL | 2 |
| Ping, WC | 2 |
| Santos, SR | 2 |
| de Fijter, WM | 1 |
| de Fijter, CW | 1 |
| Oe, PL | 1 |
| ter Wee, PM | 1 |
| Donker, AJ | 1 |
| Harman, AW | 1 |
| Penhall, RK | 1 |
| Priestly, BG | 1 |
| Frewin, DB | 1 |
| Phillips, PJ | 1 |
| Clarkson, AR | 1 |
| van Peer, AP | 1 |
| Belpaire, FM | 1 |
| Bogaert, MG | 1 |
| Gibaldi, M | 1 |
| Maddocks, JL | 1 |
| Wake, CJ | 1 |
| Harber, MJ | 1 |
| Nicholson, PA | 1 |
| Karim, A | 1 |
| Smith, M | 1 |
| Tvedegaard, E | 1 |
| Poulsen, HE | 1 |
| Vilstrup, H | 1 |
| Thomsen, HK | 1 |
| Teunissen, MW | 1 |
| Kampf, D | 1 |
| Roots, I | 1 |
| Vermeulen, NP | 1 |
| Breimer, DD | 1 |
| Bengtsson, U | 1 |
1 trial available for antipyrine and Chronic Kidney Failure
| Article | Year |
|---|---|
Influence of renal failure on cytochrome P450 activity in hypertensive patients using a "cocktail" of antipyrine and nifedipine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antipyrine; Biotransformati | 1996 |
12 other studies available for antipyrine and Chronic Kidney Failure
| Article | Year |
|---|---|
Antipyrine kinetics in Nigerian women in chronic renal failure.
Topics: Adolescent; Adult; Antipyrine; Creatinine; Female; Humans; Kidney Failure, Chronic; Kinetics; Middle | 1982 |
Effect of renal failure and bis(2-ethylhexyl) phthalate pretreatment on the disposition and metabolism of antipyrine in the rat.
Topics: Animals; Antipyrine; Corn Oil; Creatinine; Diethylhexyl Phthalate; Hemeproteins; Kidney Failure, Chr | 1984 |
Assessment of total body water and lean body mass from anthropometry, Watson formula, creatinine kinetics, and body electrical impedance compared with antipyrine kinetics in peritoneal dialysis patients.
Topics: Adult; Anthropometry; Antipyrine; Biometry; Body Composition; Body Mass Index; Body Water; Creatinin | 1997 |
Determination of antipyrine and metabolites in plasma of a patient with mild renal failure.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Chromatography, High Pressure Liquid; Ed | 1997 |
Salivary antipyrine kinetics in hepatic and renal disease and in patients on anticonvulsant therapy.
Topics: Adult; Aged; Anticonvulsants; Antipyrine; Chronic Disease; Female; Half-Life; Humans; Kidney Failure | 1977 |
In vitro hepatic oxidative metabolism of antipyrine, phenytoin and phenylbutazone in rabbits with experimental renal failure.
Topics: Animals; Antipyrine; In Vitro Techniques; Kidney Failure, Chronic; Kinetics; Liver; Oxidation-Reduct | 1978 |
Drug distribution in renal failure.
Topics: Antipyrine; Clofibrate; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Kidney Failure, Ch | 1977 |
The plasma half-life of antipyrine in chromic uraemic and normal subjects.
Topics: Administration, Oral; Adolescent; Adult; Antipyrine; Enzyme Induction; Female; Half-Life; Humans; In | 1975 |
Pharmacokinetics of misoprostol in the elderly, in patients with renal failure and when coadministered with NSAID or antipyrine, propranolol or diazepam.
Topics: Adult; Aged; Aging; Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Diazepam; Drug | 1990 |
Functional status of the liver during chronic renal failure: an experimental study in the rabbit.
Topics: Animals; Antipyrine; Body Weight; Edetic Acid; Galactose; Kidney Failure, Chronic; Liver; Male; Meta | 1985 |
Antipyrine metabolite formation and excretion in patients with chronic renal failure.
Topics: Adult; Aged; Antipyrine; Edaravone; Female; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Ma | 1985 |
Phenacetin and renal pelvic carcinoma.
Topics: Age Factors; Antipyrine; Caffeine; Female; Humans; Kidney Failure, Chronic; Kidney Neoplasms; Kidney | 1974 |