antipyrine has been researched along with Cardiovascular Diseases in 7 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Edaravone has preventive effects on myocardial injury following ischemia and reperfusion in patients with acute myocardial infarction." | 6.43 | Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases. ( Chayama, K; Higashi, Y; Jitsuiki, D; Yoshizumi, M, 2006) |
| "Edaravone was originally developed as a potent free radical scavenger, and has been widely used to treat acute ischemic stroke in Japan since 2001." | 4.89 | The efficacy of edaravone (radicut), a free radical scavenger, for cardiovascular disease. ( Kikuchi, K; Morioka, M; Murai, Y; Takeshige, N; Tanaka, E; Tancharoen, S; Yoshitomi, M, 2013) |
| "Edaravone has been recognized as a potential protective agent for cardiovascular diseases." | 3.78 | A hypothesis: Edaravone exert cardioprotection partly via modulation of adiponectin. ( Jia, M; Pei, H; Sun, L; Zheng, X; Zhou, H, 2012) |
| "Edaravone has preventive effects on myocardial injury following ischemia and reperfusion in patients with acute myocardial infarction." | 2.43 | Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases. ( Chayama, K; Higashi, Y; Jitsuiki, D; Yoshizumi, M, 2006) |
| "Four caffeine-treated rats had histologic evidence of acute myocardial infarction which was not found in any of the other rats." | 1.26 | Cardiovascular lesions in Sprague-Dawley rats induced by long-term treatment with caffeine. ( Johansson, S, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kikuchi, K | 2 |
| Tancharoen, S | 2 |
| Takeshige, N | 1 |
| Yoshitomi, M | 1 |
| Morioka, M | 1 |
| Murai, Y | 1 |
| Tanaka, E | 1 |
| Uchikado, H | 1 |
| Miyagi, N | 1 |
| Morimoto, Y | 1 |
| Ito, T | 1 |
| Miura, N | 1 |
| Miyata, K | 1 |
| Sakamoto, R | 1 |
| Kikuchi, C | 1 |
| Iida, N | 1 |
| Shiomi, N | 1 |
| Kuramoto, T | 1 |
| Kawahara, K | 1 |
| Pei, H | 1 |
| Jia, M | 1 |
| Sun, L | 1 |
| Zheng, X | 1 |
| Zhou, H | 1 |
| Higashi, Y | 1 |
| Jitsuiki, D | 1 |
| Chayama, K | 1 |
| Yoshizumi, M | 1 |
| Johansson, S | 1 |
| Tabrizchi, R | 1 |
| Adamska-Dyniewska, H | 1 |
| Kowalczyk, L | 1 |
4 reviews available for antipyrine and Cardiovascular Diseases
| Article | Year |
|---|---|
The efficacy of edaravone (radicut), a free radical scavenger, for cardiovascular disease.
Topics: Animals; Antipyrine; Cardiovascular Diseases; Edaravone; Free Radical Scavengers; Gene Expression; H | 2013 |
Beyond neurological disease: new targets for edaravone (Review).
Topics: Animals; Antipyrine; Apoptosis; Cardiovascular Diseases; Edaravone; Free Radical Scavengers; Free Ra | 2011 |
Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases.
Topics: Animals; Antioxidants; Antipyrine; Cardiovascular Diseases; Cerebrovascular Disorders; Edaravone; En | 2006 |
Edaravone Mitsubishi-Tokyo.
Topics: Antipyrine; Cardiovascular Diseases; Clinical Trials as Topic; Contraindications; Drugs, Investigati | 2000 |
3 other studies available for antipyrine and Cardiovascular Diseases
| Article | Year |
|---|---|
A hypothesis: Edaravone exert cardioprotection partly via modulation of adiponectin.
Topics: Adiponectin; Antipyrine; Cardiotonic Agents; Cardiovascular Diseases; Edaravone; Free Radical Scaven | 2012 |
Cardiovascular lesions in Sprague-Dawley rats induced by long-term treatment with caffeine.
Topics: Acetaminophen; Animals; Antipyrine; Caffeine; Cardiovascular Diseases; Heart; Male; Myocardial Infar | 1981 |
[Correlations of kinetics of antipyrine, indocyanine green and bromosulfophthalein in healthy subjects and in patients with cardiovascular diseases].
Topics: Adult; Aged; Antipyrine; Cardiovascular Diseases; Female; Humans; Indocyanine Green; Kinetics; Male; | 1978 |