antipyrine has been researched along with Blood Poisoning in 9 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sepsis was induced by cecal ligation and puncture (CLP) and the mice were divided into three groups-CLP vehicle (CLPV), CLP and edaravone (MCI-186, 3-methyl-1-phenyl-2-pyrazolin-5-one) (CLPE), and sham-operated (Sham)." | 5.42 | Metabolomic Analyses of Brain Tissue in Sepsis Induced by Cecal Ligation Reveal Specific Redox Alterations--Protective Effects of the Oxygen Radical Scavenger Edaravone. ( Chijiiwa, M; Elmér, E; Hara, N; Inazu, M; Ishida, Y; Karlsson, M; Kuroda, M; Ogiwara, Y; Sjovall, F; Uchino, H; Yara, M, 2015) |
| "Sepsis is a major clinical challenge and septic encephalopathy is its nasty complication." | 5.38 | Neurodegenerative evidence in mice brains with cecal ligation and puncture-induced sepsis: preventive effect of the free radical scavenger edaravone. ( Chiba, S; Hattori, Y; Sagara, H; Takano, Y; Takashina, M; Tomita, K; Yagisita, S; Yokoo, H, 2012) |
| "Neonatal sepsis is complicated by pulmonary hypertension." | 5.37 | Edaravone, a hydroxyl radical scavenger, ameliorates the severity of pulmonary hypertension in a porcine model of neonatal sepsis. ( Daoud, GA; Fukuda, S; Goto, T; Hashimoto, T; Hussein, MH; Ito, T; Kakita, H; Kato, I; Kato, S; Mizuno, H; Suzuki, S; Togari, H; Yamaguchi, S, 2011) |
| "A retrospective review was carried out of 207 Japanese patients with acute stroke who developed renal disorders on edaravone treatment." | 3.74 | Clinical analysis of 207 patients who developed renal disorders during or after treatment with edaravone reported during post-marketing surveillance. ( Hishida, A, 2007) |
| "Fifty-one consecutive children with sepsis and six critically ill children without sepsis were enrolled and given 18 mg/kg antipyrine per NG." | 3.72 | Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure. ( Burckart, GJ; Carcillo, JA; Doughty, L; Frye, RF; Kaplan, SS; Kofos, D; Sasser, H, 2003) |
| "Sepsis was induced by cecal ligation and puncture (CLP) and the mice were divided into three groups-CLP vehicle (CLPV), CLP and edaravone (MCI-186, 3-methyl-1-phenyl-2-pyrazolin-5-one) (CLPE), and sham-operated (Sham)." | 1.42 | Metabolomic Analyses of Brain Tissue in Sepsis Induced by Cecal Ligation Reveal Specific Redox Alterations--Protective Effects of the Oxygen Radical Scavenger Edaravone. ( Chijiiwa, M; Elmér, E; Hara, N; Inazu, M; Ishida, Y; Karlsson, M; Kuroda, M; Ogiwara, Y; Sjovall, F; Uchino, H; Yara, M, 2015) |
| "Sepsis is a major clinical challenge and septic encephalopathy is its nasty complication." | 1.38 | Neurodegenerative evidence in mice brains with cecal ligation and puncture-induced sepsis: preventive effect of the free radical scavenger edaravone. ( Chiba, S; Hattori, Y; Sagara, H; Takano, Y; Takashina, M; Tomita, K; Yagisita, S; Yokoo, H, 2012) |
| "Neonatal sepsis is complicated by pulmonary hypertension." | 1.37 | Edaravone, a hydroxyl radical scavenger, ameliorates the severity of pulmonary hypertension in a porcine model of neonatal sepsis. ( Daoud, GA; Fukuda, S; Goto, T; Hashimoto, T; Hussein, MH; Ito, T; Kakita, H; Kato, I; Kato, S; Mizuno, H; Suzuki, S; Togari, H; Yamaguchi, S, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, L | 1 |
| Song, Y | 1 |
| Zhao, M | 1 |
| Yi, Z | 1 |
| Zeng, Q | 1 |
| Hara, N | 1 |
| Chijiiwa, M | 1 |
| Yara, M | 1 |
| Ishida, Y | 1 |
| Ogiwara, Y | 1 |
| Inazu, M | 1 |
| Kuroda, M | 1 |
| Karlsson, M | 1 |
| Sjovall, F | 1 |
| Elmér, E | 1 |
| Uchino, H | 1 |
| Kato, S | 2 |
| Hussein, MH | 2 |
| Kakita, H | 2 |
| Goto, T | 2 |
| Daoud, GA | 2 |
| Kato, T | 1 |
| Sugiura, T | 1 |
| Nobata, M | 1 |
| Nakajima, Y | 1 |
| Endo, T | 1 |
| Mizuno, K | 1 |
| Ito, T | 2 |
| Kato, I | 2 |
| Suzuki, S | 2 |
| Togari, H | 2 |
| Shi, M | 1 |
| Cao, TW | 1 |
| Shen, L | 1 |
| Sun, ZD | 1 |
| Zhu, HC | 1 |
| Yamaguchi, S | 1 |
| Mizuno, H | 1 |
| Fukuda, S | 1 |
| Hashimoto, T | 1 |
| Yokoo, H | 1 |
| Chiba, S | 1 |
| Tomita, K | 1 |
| Takashina, M | 1 |
| Sagara, H | 1 |
| Yagisita, S | 1 |
| Takano, Y | 1 |
| Hattori, Y | 1 |
| Carcillo, JA | 1 |
| Doughty, L | 1 |
| Kofos, D | 1 |
| Frye, RF | 1 |
| Kaplan, SS | 1 |
| Sasser, H | 1 |
| Burckart, GJ | 1 |
| FERENCZ, P | 1 |
| BODA, D | 1 |
| Hishida, A | 1 |
9 other studies available for antipyrine and Blood Poisoning
| Article | Year |
|---|---|
Protective effects of edaravone, a free radical scavenger, on lipopolysaccharide-induced acute kidney injury in a rat model of sepsis.
Topics: Acute Kidney Injury; Animals; Antipyrine; Apoptosis; Blood Urea Nitrogen; Catalase; Cells, Cultured; | 2015 |
Metabolomic Analyses of Brain Tissue in Sepsis Induced by Cecal Ligation Reveal Specific Redox Alterations--Protective Effects of the Oxygen Radical Scavenger Edaravone.
Topics: Animals; Antipyrine; Apoptosis; bcl-2-Associated X Protein; Brain; Cecum; Cell Death; Edaravone; Fre | 2015 |
Edaravone, a novel free radical scavenger, reduces high-mobility group box 1 and prolongs survival in a neonatal sepsis model.
Topics: Animals; Animals, Newborn; Antioxidants; Antipyrine; Blood Pressure; Body Weight; Cyclic N-Oxides; E | 2009 |
[The protective effect of edaravone on the treatment of sepsis in rats].
Topics: Animals; Antipyrine; Disease Models, Animal; Edaravone; Free Radical Scavengers; Lung; Random Alloca | 2009 |
Edaravone, a hydroxyl radical scavenger, ameliorates the severity of pulmonary hypertension in a porcine model of neonatal sepsis.
Topics: Animals; Antipyrine; Blood Pressure; Edaravone; Free Radical Scavengers; Humans; Hydroxyl Radical; H | 2011 |
Neurodegenerative evidence in mice brains with cecal ligation and puncture-induced sepsis: preventive effect of the free radical scavenger edaravone.
Topics: Animals; Antipyrine; Blood-Brain Barrier; Cecum; Cytokines; Edaravone; Evans Blue; Fluorescein; Free | 2012 |
Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure.
Topics: Adolescent; Age Factors; Analysis of Variance; Antipyrine; Case-Control Studies; Child; Child, Presc | 2003 |
[Influence of pyramidone and ACTH on experimental bacteremia].
Topics: Adrenocorticotropic Hormone; Aminopyrine; Antipyrine; Bacteremia; Humans; Pseudomonas Infections; Se | 1958 |
Clinical analysis of 207 patients who developed renal disorders during or after treatment with edaravone reported during post-marketing surveillance.
Topics: Aged; Aged, 80 and over; Antipyrine; Blood Urea Nitrogen; Creatinine; Edaravone; Female; Free Radica | 2007 |