Page last updated: 2024-10-22

antipyrine and Blood Clot

antipyrine has been researched along with Blood Clot in 9 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Research Excerpts

ExcerptRelevanceReference
" The free-radical scavenger edaravone is used in combination with the recombinant tissue plasminogen activator alteplase to treat acute ischemic stroke."7.81The free-radical scavenger edaravone accelerates thrombolysis with alteplase in an experimental thrombosis model. ( Ishii, H; Sakamoto, K; Sato, T; Yamamoto, J; Yamashita, T, 2015)
" The free-radical scavenger edaravone is used in combination with the recombinant tissue plasminogen activator alteplase to treat acute ischemic stroke."3.81The free-radical scavenger edaravone accelerates thrombolysis with alteplase in an experimental thrombosis model. ( Ishii, H; Sakamoto, K; Sato, T; Yamamoto, J; Yamashita, T, 2015)
"The effects of ozagrel (CAS 82571-53-7), a thromboxane A2-synthetase inhibitor, and norphenazone (CAS 89-25-8), a free-radical scavenger, on cerebral infarction were assessed using the suture-induced middle cerebral artery occlusion (MCAO) model and a microthrombosis model."3.72Effect of ozagrel, a selective thromboxane A2-synthetase inhibitor, on cerebral infarction in rats. Comparative study with norphenazone, a free-radical scavenger. ( Ichikawa, K; Imamura, T; Kiguchi, S; Kobayashi, K; Kojima, M; Yamazaki, Y, 2003)
" Most importantly, 3d possessed a very high absolute bioavailability and was rapidly distributed in brain tissue to keep high plasma drug concentration for the treatment of ischemic strokes."1.42Discovery of 3-n-butyl-2,3-dihydro-1H-isoindol-1-one as a potential anti-ischemic stroke agent. ( Lan, Z; Lei, M; Li, J; Liang, Z; Xu, W; Xu, X; Zhang, X; Zhao, C, 2015)
"On day after discharge, he developed cerebral infarction and showed persistence of multiple left ventricular thrombi."1.40Multiple left ventricular thrombi in a patient with dilated cardiomyopathy and cerebral infarction: a case report. ( Mine, T; Miyake, H; Sato, I, 2014)
"A 68-year-old man with left cervical internal carotid artery stenosis suffered crescendo transient ischemic attacks caused by mobile thrombus detected by carotid echography and secondary impairment of cerebral hemodynamic reserve demonstrated by positron emission tomography."1.34Urgent endarterectomy using pretreatment with free radical scavenger, edaravone, and early clamping of the parent arteries for cervical carotid artery stenosis with crescendo transient ischemic attacks caused by mobile thrombus and hemodynamic cerebral is ( Inoue, T; Kobayashi, M; Komoribayashi, N; Ogasawara, K; Ogawa, A; Saito, H; Suga, Y, 2007)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mine, T1
Sato, I1
Miyake, H1
Yamashita, T2
Sato, T1
Sakamoto, K1
Ishii, H1
Yamamoto, J2
Lan, Z1
Xu, X1
Xu, W1
Li, J1
Liang, Z1
Zhang, X1
Lei, M1
Zhao, C1
Mishina, M1
Komaba, Y1
Kobayashi, S1
Kominami, S1
Fukuchi, T1
Mizunari, T1
Teramoto, A1
Katayama, Y1
GORDH, T1
Imamura, T1
Kiguchi, S1
Kobayashi, K1
Ichikawa, K1
Yamazaki, Y1
Kojima, M1
Shoge, M1
Oda, E1
Yamamoto, Y1
Giddings, JC1
Kashiwagi, S1
Suematsu, M1
Kobayashi, M1
Ogasawara, K1
Inoue, T1
Saito, H1
Komoribayashi, N1
Suga, Y1
Ogawa, A1
Aonuma, S1
Kohama, Y1
Fujimoto, S1
Nomura, M1
Yamahata, E1

Other Studies

9 other studies available for antipyrine and Blood Clot

ArticleYear
Multiple left ventricular thrombi in a patient with dilated cardiomyopathy and cerebral infarction: a case report.
    Journal of medical case reports, 2014, Sep-13, Volume: 8

    Topics: Aged; Anticoagulants; Antipyrine; Cardiomyopathy, Dilated; Cerebral Infarction; Edaravone; Heart Dis

2014
The free-radical scavenger edaravone accelerates thrombolysis with alteplase in an experimental thrombosis model.
    Thrombosis research, 2015, Volume: 135, Issue:6

    Topics: Animals; Antipyrine; Disease Models, Animal; Edaravone; Fibrinolysis; Fibrinolytic Agents; Free Radi

2015
Discovery of 3-n-butyl-2,3-dihydro-1H-isoindol-1-one as a potential anti-ischemic stroke agent.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Antioxidants; Antipyrine; Behavior, Animal; Benzofurans; Biological Availability; Brain; Ca

2015
Administration of free radical scavenger edaravone associated with higher frequency of hemorrhagic transformation in patients with cardiogenic embolism.
    Neurologia medico-chirurgica, 2008, Volume: 48, Issue:7

    Topics: Aged; Aged, 80 and over; Antipyrine; Cerebral Hemorrhage; Dose-Response Relationship, Drug; Edaravon

2008
[LOCAL COMPLICATIONS OF INTRAVENOUS ANESTHESIA].
    Svenska lakartidningen, 1964, Apr-01, Volume: 61

    Topics: Anesthesia; Anesthesia, Intravenous; Anesthetics; Antipyrine; Glycerol; Hexobarbital; Humans; Inject

1964
Effect of ozagrel, a selective thromboxane A2-synthetase inhibitor, on cerebral infarction in rats. Comparative study with norphenazone, a free-radical scavenger.
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:10

    Topics: Animals; Antipyrine; Edaravone; Enzyme Inhibitors; Free Radical Scavengers; Infarction, Middle Cereb

2003
The free-radical scavenger, edaravone, augments NO release from vascular cells and platelets after laser-induced, acute endothelial injury in vivo.
    Platelets, 2006, Volume: 17, Issue:3

    Topics: Animals; Antipyrine; Edaravone; Electrochemistry; Endothelium, Vascular; Fluorescein; Free Radical S

2006
Urgent endarterectomy using pretreatment with free radical scavenger, edaravone, and early clamping of the parent arteries for cervical carotid artery stenosis with crescendo transient ischemic attacks caused by mobile thrombus and hemodynamic cerebral is
    Neurologia medico-chirurgica, 2007, Volume: 47, Issue:3

    Topics: Aged; Antipyrine; Carotid Stenosis; Edaravone; Endarterectomy, Carotid; Free Radical Scavengers; Hum

2007
Studies on aspirin derivatives with very little side effect. IV. Inhibitory effect of aspirin-isopropylantipyrine (AIA) on several experimental thromboses.
    Journal of pharmacobio-dynamics, 1983, Volume: 6, Issue:1

    Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Antipyrine; Arachidonic Acid; Arachidonic Acids;

1983