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antipyrine and Bile Duct Obstruction, Extrahepatic

antipyrine has been researched along with Bile Duct Obstruction, Extrahepatic in 3 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Research Excerpts

ExcerptRelevanceReference
" laboratory and pharmacodynamic tests, as well as pharmacokinetic assays, were performed before the operation as well as 10-12 days after the bile duct ligation."1.29Pharmacokinetics of phenazone (antipyrine) in rabbits with experimental common bile duct obstruction. ( Barcew-Wiszniewska, B; Droździk, M; Gawrońska-Szklarz, B; Rózewicka, L; Skowron, J; Sulikowski, T; Wójcicki, J; Wójcicki, M, 1996)
"Antipyrine elimination was studied in 29 patients with obstructive jaundice Antipyrine half-lives calculated using plasma concentrations at four and 24 hours ('short antipyrine test') were significantly correlated with those calculated using six time points (p less than 0."1.26Antipyrine elimination as a dynamic test of hepatic functional integrity in obstructive jaundice. ( Benjamin, IS; Blumgart, LH; Boobis, AR; Brodie, MJ; Hampden, C; McPherson, GA, 1982)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McPherson, GA1
Benjamin, IS1
Boobis, AR1
Brodie, MJ1
Hampden, C1
Blumgart, LH1
Miguet, JP1
Vuitton, D1
Deschamps, JP1
Allemand, H1
Joanne, C1
Bechtel, P1
Carayon, P1
Wójcicki, J1
Sulikowski, T1
Wójcicki, M1
Droździk, M1
Gawrońska-Szklarz, B1
Barcew-Wiszniewska, B1
Skowron, J1
Rózewicka, L1

Other Studies

3 other studies available for antipyrine and Bile Duct Obstruction, Extrahepatic

ArticleYear
Antipyrine elimination as a dynamic test of hepatic functional integrity in obstructive jaundice.
    Gut, 1982, Volume: 23, Issue:9

    Topics: Adult; Aged; Antipyrine; Bilirubin; Cholestasis, Extrahepatic; Female; Half-Life; Humans; Liver Func

1982
Cholestasis and hepatic drug metabolism. Comparison of metabolic clearance rate of antipyrine in patients with intrahepatic or extrahepatic cholestasis.
    Digestive diseases and sciences, 1981, Volume: 26, Issue:8

    Topics: Adult; Aged; Antipyrine; Cholestasis, Extrahepatic; Cholestasis, Intrahepatic; Female; Humans; Injec

1981
Pharmacokinetics of phenazone (antipyrine) in rabbits with experimental common bile duct obstruction.
    British journal of pharmacology, 1996, Volume: 117, Issue:1

    Topics: Animals; Antipyrine; Biotransformation; Cholestasis, Extrahepatic; Common Bile Duct; Half-Life; Live

1996