antipyrine has been researched along with Autoimmune Diabetes in 7 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Edaravone is a potent scavenger of hydroxyl radicals and attenuates oxidative damage-related neurodegenerative diseases." | 1.35 | The radical scavenger edaravone counteracts diabetes in multiple low-dose streptozotocin-treated mice. ( Ago, Y; Fukudome, D; Kawasaki, T; Matsuda, M; Matsuda, T, 2008) |
| "Antipyrine is a useful marker drug for cytochrome P-450 dependent hepatic drug metabolism." | 1.28 | Hepatic drug metabolism is increased in poorly controlled insulin-dependent diabetes mellitus. ( Goldstein, S; Saenger, P; Simpson, A, 1990) |
| "Antipyrine elimination was studied in 11 type I and 10 type II diabetic patients and 2 age-matched control groups." | 1.28 | Differential effect of type I and type II diabetes mellitus on antipyrine elimination. ( Adithan, C; Bapna, JS; Chandrasekar, S; Danda, D; Shashindran, CH; Swaminathan, RP, 1989) |
| " Thus, the drug-metabolizing capacity in diabetics seems to be markedly reduced, and drug dosage might have to take account of this fact." | 1.27 | [Antipyrine clearance as a measure of drug metabolism in patients with diabetes mellitus]. ( Dennin, DE; Oltmanns, D; Pentz, R; Siegers, CP, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukudome, D | 1 |
| Matsuda, M | 1 |
| Kawasaki, T | 1 |
| Ago, Y | 1 |
| Matsuda, T | 1 |
| Oltmanns, D | 1 |
| Dennin, DE | 1 |
| Pentz, R | 1 |
| Siegers, CP | 1 |
| Sotaniemi, EA | 1 |
| Pelkonen, O | 1 |
| Arranto, AJ | 1 |
| Tapanainen, P | 1 |
| Rautio, A | 1 |
| Pasanen, M | 1 |
| Kuhn, DC | 1 |
| Walenga, RW | 1 |
| Stuart, MJ | 1 |
| Goldstein, S | 1 |
| Simpson, A | 1 |
| Saenger, P | 1 |
| Adithan, C | 1 |
| Danda, D | 1 |
| Shashindran, CH | 1 |
| Bapna, JS | 1 |
| Swaminathan, RP | 1 |
| Chandrasekar, S | 1 |
| Zysset, T | 1 |
| Wietholtz, H | 1 |
1 trial available for antipyrine and Autoimmune Diabetes
| Article | Year |
|---|---|
Diabetes and elimination of antipyrine in man: an analysis of 298 patients classified by type of diabetes, age, sex, duration of disease and liver involvement.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Blood Glu | 2002 |
6 other studies available for antipyrine and Autoimmune Diabetes
| Article | Year |
|---|---|
The radical scavenger edaravone counteracts diabetes in multiple low-dose streptozotocin-treated mice.
Topics: Animals; Antipyrine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Edar | 2008 |
[Antipyrine clearance as a measure of drug metabolism in patients with diabetes mellitus].
Topics: Adolescent; Adult; Aged; Antipyrine; Diabetes Mellitus, Type 1; Fatty Liver; Humans; Liver Cirrhosis | 1984 |
A prostacyclin analogue crosses the in vitro perfused human placenta and improves transfer in some pathologic states.
Topics: Antipyrine; Diabetes Mellitus, Type 1; Epoprostenol; Female; Humans; Hypertension; Ibuprofen; In Vit | 1991 |
Hepatic drug metabolism is increased in poorly controlled insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Antipyrine; Child; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glycated | 1990 |
Differential effect of type I and type II diabetes mellitus on antipyrine elimination.
Topics: Adolescent; Adult; Antipyrine; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitu | 1989 |
Differential effect of type I and type II diabetes on antipyrine disposition in man.
Topics: Adult; Aged; Aged, 80 and over; Antipyrine; Biotransformation; Diabetes Mellitus, Type 1; Diabetes M | 1988 |