antipyrine has been researched along with Aura in 20 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors studied antipyrine disposition before and after delivery in 4 epileptic women whose anticonvulsant plasma level per dosage ratio was lowered during pregnancy, and compared the results to those found in nonpregnant women undergoing antiepileptic treatment (N = 6) and healthy women (N = 6)." | 7.66 | Antipyrine disposition in relation to lowered anticonvulsant plasma level during pregnancy. ( Chiba, K; Ishizaki, T; Nakazawa, Y; Tabuchi, T; Wagatsuma, T, 1982) |
| "We determined changes in serum concentrations of thyroid hormones during carbamazepine (CBZ) therapy during a 5-year prospective follow-up study of 20 patients with newly diagnosed epilepsy." | 3.69 | Thyroid and myocardial function after replacement of carbamazepine by oxcarbazepine. ( Airaksinen, KE; Isojärvi, JI; Mustonen, JN; Myllylä, VV; Pakarinen, AJ; Pelkonen, O; Rautio, A, 1995) |
| "The authors studied antipyrine disposition before and after delivery in 4 epileptic women whose anticonvulsant plasma level per dosage ratio was lowered during pregnancy, and compared the results to those found in nonpregnant women undergoing antiepileptic treatment (N = 6) and healthy women (N = 6)." | 3.66 | Antipyrine disposition in relation to lowered anticonvulsant plasma level during pregnancy. ( Chiba, K; Ishizaki, T; Nakazawa, Y; Tabuchi, T; Wagatsuma, T, 1982) |
| " Antipyrine t1/2 did not distinguish epileptics with osteomalacia from other epileptic patients and half-lives were similar in patients treated with phenytoin and a barbiturate to those in patients on phenytoin alone." | 3.66 | Antiopyrine half-life as a measure of hepatic enzyme induction: clinical applications in a chronic epileptic population. ( Byrne, E; Frewin, DB; Hallpike, JF; Harman, AW, 1979) |
| "Phenytoin treatment may impair the validity of the caffeine liver function test." | 1.28 | Effect of phenytoin, carbamazepine, and valproic acid on caffeine metabolism. ( Büchsel, R; Kohl, D; Kreiten, K; Matern, S; Wietholtz, H; Zysset, T, 1989) |
| " Significant positive correlations were found between the dosage of CBZ, DPH, PMD and PB and both indices of enzyme induction." | 1.27 | A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients. ( Hedges, A; Makki, KA; Perucca, E; Richens, A; Ruprah, M; Wilson, JF, 1984) |
| "Felodipine is a dihydropyridine calcium antagonist, structurally related to nifedipine, which undergoes extensive first-pass hepatic metabolism and normally has an oral bioavailability of 15%." | 1.27 | Reduced felodipine bioavailability in patients taking anticonvulsants. ( Capewell, S; Critchley, JA; Freestone, S; Pottage, A; Prescott, LF, 1988) |
| " The half-life of chlorpropamide was significantly shorter in the patients (34." | 1.27 | Pharmacokinetics of chlorpropamide in epileptic patients: effects of enzyme induction and urine pH on chlorpropamide elimination. ( Kärkkäinen, S; Lehtovaara, R; Neuvonen, PJ, 1987) |
| " Of the generally used measures of enzyme induction (oral clearance, oral half-life and intravenous half-life) oral clearance was the most closely related to the intravenous clearance of antipyrine (r = 0." | 1.27 | Pharmacokinetics of antipyrine in epileptic patients. ( Richens, A; Rimmer, EM; Routledge, PA; Tsanaclis, LM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (85.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Vasconcelos, AP | 1 |
| Bouilleret, V | 1 |
| Riban, V | 1 |
| Wasterlain, C | 1 |
| Nehlig, A | 1 |
| Miyamoto, R | 1 |
| Shimakawa, S | 1 |
| Suzuki, S | 1 |
| Ogihara, T | 1 |
| Tamai, H | 1 |
| Perucca, E | 1 |
| Hedges, A | 2 |
| Makki, KA | 2 |
| Ruprah, M | 1 |
| Wilson, JF | 1 |
| Richens, A | 3 |
| Chiba, K | 1 |
| Ishizaki, T | 1 |
| Tabuchi, T | 1 |
| Wagatsuma, T | 1 |
| Nakazawa, Y | 1 |
| Goldberg, DM | 1 |
| Isojärvi, JI | 1 |
| Airaksinen, KE | 1 |
| Mustonen, JN | 1 |
| Pakarinen, AJ | 1 |
| Rautio, A | 1 |
| Pelkonen, O | 1 |
| Myllylä, VV | 1 |
| Oxley, J | 1 |
| Monks, A | 1 |
| Byrne, E | 1 |
| Harman, AW | 1 |
| Frewin, DB | 1 |
| Hallpike, JF | 1 |
| Sotaniemi, EA | 2 |
| Pelkonen, RO | 1 |
| Ahokas, J | 1 |
| Pirttiaho, HI | 2 |
| Ahlqvist, J | 1 |
| Ahokas, JT | 1 |
| Pitkänen, U | 1 |
| Petruch, F | 3 |
| Schüppel, RV | 3 |
| Welch, RM | 2 |
| DeAngelis, RL | 2 |
| Wingfield, M | 1 |
| Farmer, TW | 2 |
| Wietholtz, H | 1 |
| Zysset, T | 1 |
| Kreiten, K | 1 |
| Kohl, D | 1 |
| Büchsel, R | 1 |
| Matern, S | 1 |
| Capewell, S | 1 |
| Freestone, S | 1 |
| Critchley, JA | 1 |
| Pottage, A | 1 |
| Prescott, LF | 1 |
| Acheson, DW | 1 |
| Uden, S | 1 |
| Braganza, JM | 1 |
| Brown, SW | 1 |
| Houston, JB | 1 |
| Neuvonen, PJ | 1 |
| Kärkkäinen, S | 1 |
| Lehtovaara, R | 1 |
| Rimmer, EM | 1 |
| Routledge, PA | 1 |
| Tsanaclis, LM | 1 |
| Steinhilber, G | 1 |
1 review available for antipyrine and Aura
| Article | Year |
|---|---|
The expanding role of microsomal enzyme induction, and its implications for clinical chemistry.
Topics: Acetaminophen; Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Electron Transport; E | 1980 |
19 other studies available for antipyrine and Aura
| Article | Year |
|---|---|
Role of nitric oxide in cerebral blood flow changes during kainate seizures in mice: genetic and pharmacological approaches.
Topics: Animals; Antipyrine; Brain; Cerebral Cortex; Cerebrovascular Circulation; Convulsants; Disease Model | 2005 |
Edaravone prevents kainic acid-induced neuronal death.
Topics: Aldehydes; Animals; Antipyrine; Brain; Cell Death; Disease Models, Animal; Down-Regulation; Edaravon | 2008 |
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients.
Topics: Anticonvulsants; Antipyrine; Carbamazepine; Enzyme Induction; Epilepsy; Female; Glucaric Acid; Half- | 1984 |
Antipyrine disposition in relation to lowered anticonvulsant plasma level during pregnancy.
Topics: Adult; Anticonvulsants; Antipyrine; Delivery, Obstetric; Dose-Response Relationship, Drug; Epilepsy; | 1982 |
Thyroid and myocardial function after replacement of carbamazepine by oxcarbazepine.
Topics: Adolescent; Adult; Anticonvulsants; Antipyrine; Carbamazepine; Cytochrome P-450 Enzyme System; Echoc | 1995 |
Lack of hepatic enzyme inducing effect of sodium valproate.
Topics: Adult; Antipyrine; Enzyme Induction; Epilepsy; Female; Glucaric Acid; Half-Life; Humans; Liver; Male | 1979 |
Antiopyrine half-life as a measure of hepatic enzyme induction: clinical applications in a chronic epileptic population.
Topics: Adult; Antipyrine; Barbiturates; Enzyme Induction; Epilepsy; Female; Half-Life; Humans; Male; Micros | 1979 |
Drug metabolism in epileptics: in vivo and in vitro correlations.
Topics: Adult; Antipyrine; Cytochrome P-450 Enzyme System; Epilepsy; Female; Half-Life; Humans; In Vitro Tec | 1978 |
Liver size and indices of drug metabolism in epileptics.
Topics: Adult; Antipyrine; Cytochrome P-450 Enzyme System; Epilepsy; Female; Humans; Kinetics; Liver; Male; | 1978 |
[Effects of anticonvulsive treatment on drug elimination in man. Induction of liver hydroxylating enzyme system by diphenylhydantoin and carbamazepine].
Topics: Adult; Antipyrine; Bilirubin; Carbamazepine; Creatinine; Epilepsy; Female; Half-Life; Humans; Hydrox | 1975 |
Elimination of antipyrine from saliva as a measure of metabolism in man.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Antipyrine; Epilepsy; Half-Life; Humans; Kinetics; Midd | 1975 |
Effect of anticonvulsant drugs on the drug metabolism in man as measured by the elimination rate of antipyrine from saliva.
Topics: Anticonvulsants; Antipyrine; Epilepsy; Humans; Saliva | 1975 |
Effect of phenytoin, carbamazepine, and valproic acid on caffeine metabolism.
Topics: Adolescent; Adult; Aged; Antipyrine; Caffeine; Carbamazepine; Cytochrome P-450 Enzyme System; Enzyme | 1989 |
Reduced felodipine bioavailability in patients taking anticonvulsants.
Topics: Administration, Oral; Adult; Anticonvulsants; Antipyrine; Biological Availability; Drug Administrati | 1988 |
Theophylline and antipyrine disposition in smoking and non-smoking epileptic subjects.
Topics: Adult; Antipyrine; Epilepsy; Female; Half-Life; Humans; Male; Middle Aged; Smoking; Theophylline | 1987 |
Pharmacokinetics of chlorpropamide in epileptic patients: effects of enzyme induction and urine pH on chlorpropamide elimination.
Topics: Adult; Anticonvulsants; Antipyrine; Chlorpropamide; Enzyme Induction; Epilepsy; Female; Half-Life; H | 1987 |
Pharmacokinetics of antipyrine in epileptic patients.
Topics: Administration, Oral; Adolescent; Adult; Antipyrine; Biological Availability; Epilepsy; Female; Half | 1986 |
[Enhanced drug hydroxylation in man under diphenyl-hydantoin therapy].
Topics: Administration, Oral; Antipyrine; Biodegradation, Environmental; Creatinine; Epilepsy; Epilepsy, Ton | 1974 |
Effect of diphenylhydantoin on hepatic drug hydroxylation.
Topics: Adult; Antipyrine; Bilirubin; Colorimetry; Creatinine; Epilepsy; Half-Life; Humans; Hydroxylation; J | 1974 |