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antipyrine and Asthma

antipyrine has been researched along with Asthma in 28 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Fifteen otherwise healthy asthmatics with reversible airway obstruction were treated with salbutamol (8 mg slow release twice daily) and theophylline (300 mg twice daily)."5.06Effect of theophylline and salbutamol on hepatic drug metabolism. ( Christensen, HR; Døssing, M; Evald, T; Lange, P, 1989)
"Studies of the immune status and antipyrine test helped to analyse the status of the two body detoxicants--the immune system and the system of microsomal hepatic oxygenases in petrochemical production workers suffering from the chronic bronchitis and bronchial asthma."3.68[The function of 2 detoxifying body systems in workers of the petrochemical industry]. ( Ershov, AF; Mazurov, AL; Potapova, GV; Saprykina, EV, 1992)
"An asthmatic patient required very high doses of theophylline (2."3.67Large theophylline requirements due to high theophylline clearance: verification by the antipyrine test. ( Blyden, GT; Greenblatt, DJ; LeDuc, BW, 1986)
" Salicylamide, an analgesic without effect on the prostaglandin synthesis was in the oral exposition test of 18 patients with proved analgesics-asthma-syndrome in the dosage of 500 mg subjectively and objectively tolerated without reaction."1.26[Salicylamide-- a potential pain-remedy alternative in the analgesic asthma syndrome]. ( Hummel, S; Jäger, L; Slapke, J, 1979)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199027 (96.43)18.7374
1990's1 (3.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ROZOVSKAIA, ES1
STERENSON, FN1
HERXHEIMER, H1
STRESEMANN, E2
GOECHT, R1
FRUHMANN, G1
TERPLAN, M1
BUESSOW, H1
BOTTKE, H1
GUENTHNER, W1
BERGNER, D2
ZICHA, L2
KRATSCH, H2
MILLER, P2
MAINIERI, L1
Kandt, D1
Sehrt, I1
Iwainsky, H1
Slapke, J1
Hummel, S1
Jäger, L1
Lochmann, O1
Benes, J1
Výmola, F1
Pokorný, J1
Mazurov, AL1
Potapova, GV1
Saprykina, EV1
Ershov, AF1
Døssing, M1
Evald, T1
Lange, P1
Christensen, HR1
Blyden, GT1
LeDuc, BW1
Greenblatt, DJ1
Kowalski, ML1
Rozniecki, J1
Hady, S1
Mathey, HG1
Naess, K1
Kessler, H1
Samter, M1
Beers, RF1
Iven, A1
Gürtler, J1
Hansen, P1
Pasternak, DP1
Socolow, EL1
Ingbar, SH1
Sedivec, V1
Krynyckyj, V1

Trials

1 trial available for antipyrine and Asthma

ArticleYear
Effect of theophylline and salbutamol on hepatic drug metabolism.
    Human toxicology, 1989, Volume: 8, Issue:3

    Topics: Adult; Albuterol; Antipyrine; Asthma; Coffee; Female; Humans; Liver; Male; Middle Aged; Respiratory

1989

Other Studies

27 other studies available for antipyrine and Asthma

ArticleYear
[Desensitizing action of some medicinal remedies] [pyramidon, antipyrin and salicylate in asthma].
    Farmakologiia i toksikologiia, 1945, Volume: 8, Issue:2

    Topics: Aminopyrine; Anaphylaxis; Antipyrine; Asthma; Humans; Hypersensitivity; Immune System Diseases; Sali

1945
Anti-asthmatic effect of phenazone and amidopyrine.
    Nature, 1961, Dec-16, Volume: 192

    Topics: Aminopyrine; Anti-Asthmatic Agents; Antipyrine; Asthma

1961
[Experiences with Makara, a successful antiasthmatic power].
    Die Medizinische Welt, 1962, Nov-03, Volume: 44

    Topics: Anti-Asthmatic Agents; Antipyrine; Asthma; Ephedrine; Papaverine; Phenacetin; Theophylline

1962
[THE EFFECT OF ANTIPYRETIC AND ANALGESIC SUBSTANCES ON HUMAN BRONCHIAL ASTHMA AND EXPERIMENTAL ASTHMA IN GUINEA PIGS].
    Acta allergologica, 1963, Volume: 18

    Topics: Acetylcholine; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anaphylaxis; Animals; Antipyretics

1963
[ON THE THERAPY OF BRONCHIAL ASTHMA AND ASTHMATOID BRONCHITIS.SPIROGRAPHIC AND RESPIRATORY FUNCTION STUDIES].
    Munchener medizinische Wochenschrift (1950), 1964, Feb-07, Volume: 106

    Topics: Antipyrine; Asthma; Bronchitis; Bronchodilator Agents; Caffeine; Humans; Isoproterenol; Respiratory

1964
[ON THE PROBLEM OF PSYCHOSES DUE TO ANTIASTHMATIC DRUGS].
    Der Nervenarzt, 1964, Volume: 35

    Topics: Anti-Asthmatic Agents; Antipyrine; Asthma; Atropine; Caffeine; Digitalis Glycosides; Ephedrine; Hall

1964
[EXPERIMENTAL STUDIES OF AN ASTHMA POWDER IN A DOUBLE BLIND TRIAL].
    Arzneimittel-Forschung, 1964, Volume: 14

    Topics: Antipyrine; Asthma; Biomedical Research; Bronchodilator Agents; Caffeine; Double-Blind Method; Drug

1964
[COMPARATIVE STUDIES ON ACETYLCHOLINE ANTAGONISM OF MONOPHENYLBUTAZONE, DIMETHYLAMINOETHANOL BITARTRATE, ISOPROPYLANTIPYRINE, CARISOPRODOL, TRASYLOL, RESPLANT AND PITRESSIN IN THE GUINEA PIG ASTHMA TEST. II].
    Allergie und Asthma, 1964, Volume: 10

    Topics: Acetylcholine; Amino Alcohols; Antipyrine; Aprotinin; Arginine Vasopressin; Asthma; Carisoprodol; Ch

1964
[COMPARATIVE STUDIES ON HISTAMINE AND SEROTONIN ANTAGONISM OF MONOPHENYLBUTAZONE, DIMETHYLAMINOETHANOL BITARTRATE, ISOPROPYLANTIPYRINE, CARISOPRODOL, TRASYLOL, RESPLANT AND PITRESSIN IN THE GUINEA PIG ASTHMA TEST. 1].
    Allergie und Asthma, 1964, Volume: 10

    Topics: Amino Alcohols; Antipyrine; Aprotinin; Arginine Vasopressin; Asthma; Carisoprodol; Deanol; Enzyme In

1964
[Clinical trials of the use of the combination of sulfadimethoxine and phenyl-dimethyl-dimethyl-amidoisopyrazolone orthoquinolinsulfonate].
    Gazzetta medica italiana, 1962, Volume: 121

    Topics: Antipyrine; Asthma; Bronchitis; Bronchopneumonia; Humans; Pleurisy; Respiration Disorders; Sulfadime

1962
[Possibilities for optimizing therapy with theophylline preparations. III. Ventilatory effect and pharmacokinetics of "new" Pulmophyllin].
    Zeitschrift fur Erkrankungen der Atmungsorgane, 1984, Volume: 162, Issue:1

    Topics: Adult; Aminophylline; Antipyrine; Asthma; Double-Blind Method; Drug Combinations; Female; Forced Exp

1984
Influence of dietary protein and carbohydrate on oxidative biotransformation of drugs in normal adults and children with asthma.
    Nutrition reviews, 1981, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Antipyrine; Asthma; Child; Dietary Carbohydrates; Dietary Proteins; Female; Human

1981
[Salicylamide-- a potential pain-remedy alternative in the analgesic asthma syndrome].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, Dec-01, Volume: 34, Issue:23

    Topics: Analgesics; Animals; Antipyrine; Asthma; Bronchial Spasm; Cyclooxygenase Inhibitors; Female; Guinea

1979
Observation of antibody activity against antibiotics in patients with atopic disease.
    Journal of hygiene, epidemiology, microbiology, and immunology, 1978, Volume: 22, Issue:3

    Topics: Analgesics; Anti-Bacterial Agents; Antibodies; Antipyrine; Asthma; Drug Hypersensitivity; Hemaggluti

1978
[The function of 2 detoxifying body systems in workers of the petrochemical industry].
    Gigiena truda i professional'nye zabolevaniia, 1992, Issue:8

    Topics: Adult; Antipyrine; Asthma; Bronchitis; Chemical Industry; Chronic Disease; Cytochrome P-450 Enzyme S

1992
Large theophylline requirements due to high theophylline clearance: verification by the antipyrine test.
    Pharmacology, 1986, Volume: 32, Issue:4

    Topics: Adult; Antipyrine; Asthma; Half-Life; Humans; Kinetics; Liver; Male; Theophylline

1986
[Development of aspirin tolerance in hypersensitive persons. I. Methods of development of tolerance, aspirin refraction time and cross tolerance to other drugs].
    Polskie Archiwum Medycyny Wewnetrznej, 1986, Volume: 75, Issue:1

    Topics: Antipyrine; Aspirin; Asthma; Cross Reactions; Drug Hypersensitivity; Drug Tolerance; Humans; Indomet

1986
Dipyrone in bronchial asthma.
    British medical journal, 1973, Mar-24, Volume: 1, Issue:5855

    Topics: Alkanesulfonates; Analgesics; Antipyrine; Asthma; Humans; Injections, Intravenous; Prostaglandin Ant

1973
[The therapy of the asthmatic patient with Par-Isalon].
    Der Landarzt, 1966, Feb-20, Volume: 42, Issue:5

    Topics: Antipyrine; Asthma; Bronchodilator Agents; Central Nervous System Stimulants; Ephedrine; Humans; Xan

1966
[Combinated oral antiasthmatics--how effective are they? An invitation to discussion].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1974, Nov-10, Volume: 94, Issue:31

    Topics: Administration, Oral; Antipyrine; Asthma; Caffeine; Drug Combinations; Ephedrine; Humans; Parasympat

1974
[Pediatric Asthma-Bisolvon suppositories in the treatment of asthmatic bronchitis and bronchial asthma in childhood].
    Fortschritte der Medizin, 1972, Sep-28, Volume: 90, Issue:27

    Topics: Adolescent; Antipyrine; Asthma; Barbiturates; Benzyl Compounds; Bronchitis; Child; Child, Preschool;

1972
Concerning the nature of intolerance to aspirin.
    The Journal of allergy, 1967, Volume: 40, Issue:5

    Topics: Aminopyrine; Antipyrine; Aspirin; Asthma; Chemoreceptor Cells; Drug Hypersensitivity; Edema; Histami

1967
[On drug therapy of emphysema and related diseases in more advanced age].
    Der Landarzt, 1967, Sep-20, Volume: 43, Issue:26

    Topics: Aged; Antipyrine; Asthma; Atropa belladonna; Bronchitis; Bronchodilator Agents; Humans; Papaverine;

1967
[Clinical and respiratory function technical studies of the new drug combination Asthmadyn-R in asthmatic clinical states].
    Praxis, 1967, Oct-12, Volume: 56, Issue:41

    Topics: Adult; Aged; Antipyrine; Asthma; Atropa belladonna; Bronchodilator Agents; Diphenhydramine; Ephedrin

1967
[Factory physician and bronchitis].
    Zeitschrift fur Allgemeinmedizin, 1969, Jan-10, Volume: 45, Issue:1

    Topics: Antipyrine; Asthma; Atropa belladonna; Bronchitis; Humans; Occupational Medicine; Papaverine; Phytot

1969
Synergistic interaction of phenazone and iodide on thyroid hormone biosynthesis in the rat.
    Endocrinology, 1969, Volume: 84, Issue:4

    Topics: Animals; Antipyrine; Asthma; Caffeine; Chromatography, Paper; Digitalis; Diiodotyrosine; Drug Synerg

1969
[Mental disorders in chronic Yastyl poisoning].
    Ceskoslovenska psychiatrie, 1966, Volume: 62, Issue:5

    Topics: Adult; Antipyrine; Asthma; Caffeine; Ephedrine; Humans; Male; Middle Aged; Procaine; Psychoses, Subs

1966