antipyrine has been researched along with Ascites in 5 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Ascites: Accumulation or retention of free fluid within the peritoneal cavity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this open-label study, the disposition of fleroxacin in liver disease in 12 healthy male volunteers, 6 male cirrhotics without ascites (group A), and 6 male cirrhotics with ascites (group B) was evaluated." | 7.68 | Fleroxacin pharmacokinetics in patients with liver cirrhosis. ( Blouin, RA; Foster, TS; Hamelin, BA; John, WJ; Smith, DA; Welker, HA, 1992) |
| "In this open-label study, the disposition of fleroxacin in liver disease in 12 healthy male volunteers, 6 male cirrhotics without ascites (group A), and 6 male cirrhotics with ascites (group B) was evaluated." | 3.68 | Fleroxacin pharmacokinetics in patients with liver cirrhosis. ( Blouin, RA; Foster, TS; Hamelin, BA; John, WJ; Smith, DA; Welker, HA, 1992) |
| "Antipyrine metabolism was normal or marginally impaired in patients with compensated cirrhosis or acute hepatitis, whereas it was frequently abnormal in those with chronic active hepatitis or advanced alcoholic liver disease." | 1.26 | Drug metabolism in liver disease. Identification of patients with impaired hepatic drug metabolism. ( Cooksley, WG; Farrell, GC; Hart, P; Powell, LW, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| GRAEBNER, H | 1 |
| Rector, WG | 2 |
| Everson, GT | 2 |
| Robertson, AD | 2 |
| Farrell, GC | 1 |
| Cooksley, WG | 1 |
| Hart, P | 1 |
| Powell, LW | 1 |
| Blouin, RA | 1 |
| Hamelin, BA | 1 |
| Smith, DA | 1 |
| Foster, TS | 1 |
| John, WJ | 1 |
| Welker, HA | 1 |
| Lewis, F | 1 |
5 other studies available for antipyrine and Ascites
| Article | Year |
|---|---|
[Increased effectiveness of cytosatic therapy by promoting absorption of Ehrlich ascites with 1-phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-n-butylpyrazolidine monohydrate].
Topics: Animals; Antineoplastic Agents; Antipyrine; Ascites; Carcinoma, Ehrlich Tumor; Phenylbutazone | 1963 |
Sodium retention does not occur at a critical threshold of liver function in alcoholic cirrhosis.
Topics: Antipyrine; Ascites; Blood Volume; Caffeine; Cholic Acid; Cholic Acids; Humans; Liver; Liver Cirrhos | 1994 |
Drug metabolism in liver disease. Identification of patients with impaired hepatic drug metabolism.
Topics: Acute Disease; Antipyrine; Ascites; Biotransformation; Chemical and Drug Induced Liver Injury; Chole | 1978 |
Fleroxacin pharmacokinetics in patients with liver cirrhosis.
Topics: Administration, Oral; Adult; Aged; Antipyrine; Ascites; Fleroxacin; Humans; Infusions, Intravenous; | 1992 |
Renal sodium retention complicating alcoholic liver disease: relation to portosystemic shunting and liver function.
Topics: Adult; Antipyrine; Ascites; Caffeine; Cholic Acid; Cholic Acids; Humans; Kidney; Liver; Liver Diseas | 1990 |