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antipyrine and Arthritis, Rheumatoid

antipyrine has been researched along with Arthritis, Rheumatoid in 19 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.

Research Excerpts

ExcerptRelevanceReference
"Phenylbutazone in doses of 50, 100, 200 and 400 mg/day has been given for four periods of three weeks to seven patients with rheumatoid arthritis."9.04Phenylbutazone: plasma concentrations and effectiveness in patients with rheumatoid arthritis. ( Orme, ML, 1977)
"A male patient with rheumatoid arthritis (RA) developed acute stroke and was treated with the free radical scavenger, edaravone."7.73Edaravone inhibits the disease activity in rheumatoid arthritis. ( Arii, K; Hashimoto, K; Ikeda, Y; Kumon, Y; Suehiro, T, 2006)
"Phenylbutazone in doses of 50, 100, 200 and 400 mg/day has been given for four periods of three weeks to seven patients with rheumatoid arthritis."5.04Phenylbutazone: plasma concentrations and effectiveness in patients with rheumatoid arthritis. ( Orme, ML, 1977)
"Immune reactions to citrulline-containing proteins appear to be central in the immunopathogenesis of rheumatoid arthritis."3.73Specific modification of peptide-bound citrulline residues. ( Fleckenstein, B; Holm, A; Rise, F; Sessler, N; Sollid, LM; Undheim, K, 2006)
"A male patient with rheumatoid arthritis (RA) developed acute stroke and was treated with the free radical scavenger, edaravone."3.73Edaravone inhibits the disease activity in rheumatoid arthritis. ( Arii, K; Hashimoto, K; Ikeda, Y; Kumon, Y; Suehiro, T, 2006)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199016 (84.21)18.7374
1990's0 (0.00)18.2507
2000's3 (15.79)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
FERRERO, S1
FURNO, F1
REINCKE, A1
SCHMIDT, U1
DEMARTIIS, M1
GIULIANI, A1
SAMMARTINO, V1
HART, FD1
BOARDMAN, PL1
SZIRMAI, E1
BEROVIC, Z1
NIKOLIC, J1
LOPICIC, L1
Arii, K2
Kumon, Y2
Ikeda, Y2
Suehiro, T2
Hashimoto, K2
Holm, A1
Rise, F1
Sessler, N1
Sollid, LM1
Undheim, K1
Fleckenstein, B1
Knoell, KH1
Orme, ML1
Richens, A1
Seidel, K1
Eckstein, M1
Cathcart, BJ1
Vince, JD1
Gordon, AJ1
Bell, MA1
Chalmers, IM1
Brogden, RN1
Speight, TM1
Avery, GS1
Hill, RC1
Turner, P1
Colamussi, V1
Bazzanini, G1
Fernández Nicolás, I1

Trials

5 trials available for antipyrine and Arthritis, Rheumatoid

ArticleYear
[Results of a clinical study on nicopyrone].
    Die Medizinische Welt, 1976, Nov-05, Volume: 27, Issue:45

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Arthritis, Rheumatoid; Clinical Trials a

1976
Phenylbutazone: plasma concentrations and effectiveness in patients with rheumatoid arthritis.
    The Journal of international medical research, 1977, Volume: 5 Suppl 2

    Topics: Adult; Antipyrine; Arthritis, Rheumatoid; Chromatography, Gas; Female; Half-Life; Humans; Male; Midd

1977
Studies on 2-(3-benzoylphenyl) propionic acid (Orudis). A double-blind cross-over trial in patients with rheumatoid arthritis and an assessment of its influence on hepatic drug-metabolizing enzymes.
    Annals of the rheumatic diseases, 1973, Volume: 32, Issue:1

    Topics: Anti-Inflammatory Agents; Antipyrine; Arthritis, Rheumatoid; Benzophenones; Clinical Trials as Topic

1973
Ketoprofen: a preliminary report of its pharmacological activity and therapeutic efficacy in rheumatic disorders.
    Drugs, 1974, Volume: 8, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyrine; Arthritis, Rheumatoid; Benzophenones; Bra

1974
A comparison of codeine compound and "saridone" in the pain of rheumatoid arthritis.
    The British journal of clinical practice, 1970, Volume: 24, Issue:1

    Topics: Adult; Aged; Antipyrine; Arthritis, Rheumatoid; Caffeine; Clinical Trials as Topic; Codeine; Female;

1970

Other Studies

14 other studies available for antipyrine and Arthritis, Rheumatoid

ArticleYear
[Clinical research on the action of a new preparation with a pyrazolone-pyrazolidone base].
    Minerva medica, 1960, Nov-07, Volume: 51

    Topics: Antipyrine; Arthritis; Arthritis, Rheumatoid; Back Pain; Gout; Humans; Hyperthermia, Induced; Phenyl

1960
[CLINICAL OBSERVATIONS ON THE EFFECT OF NICOPYRON AD INJECTIONEM ON DISORDERS OF THE RHEUMATIC SYMPTOM COMPLEX].
    Medizinische Klinik, 1963, Aug-30, Volume: 58

    Topics: Antipyrine; Arthritis; Arthritis, Rheumatoid; Humans; Niacinamide; Rheumatic Fever; Spondylitis; Spo

1963
[NEW POSSIBILITIES IN THE MEDICAL TREATMENT OF ORTHOPEDIC DISEASES].
    Die Medizinische Welt, 1963, Nov-02, Volume: 44

    Topics: Antipyrine; Arthritis; Arthritis, Rheumatoid; Back Pain; Bone Diseases; Carisoprodol; Cervical Verte

1963
[EXPERIMENTAL AND CLINICAL OBSERVATIONS ON THE PHENAZONE-AMINOPHENAZONE MOLECULAR ASSOCIATION].
    La Clinica terapeutica, 1964, Jan-15, Volume: 28

    Topics: Aminopyrine; Antipyrine; Arthritis; Arthritis, Rheumatoid; Biomedical Research; Chemistry, Pharmaceu

1964
TRIAL OF NIFENAZONE ("THYLIN").
    British medical journal, 1964, Jun-13, Volume: 1, Issue:5397

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antipyrine; Arthritis; Arthritis, Rheumatoid; Ni

1964
[PHARMACOLOGICAL AND EXPERIMENTAL THERAPEUTIC STUDIES ON RAPOSTAN, A WATER-SOLUBLE NICOTINAMIDE DERIVATIVE].
    Therapeutische Umschau. Revue therapeutique, 1964, Volume: 21

    Topics: Antipyrine; Arthritis; Arthritis, Rheumatoid; Camphor; Drug Therapy; Niacinamide; Rats; Research; Wa

1964
[TOMANOL THERAPY OF INFLAMMATORY AND OTHER FORMS OF RHEUMATISM].
    Srpski arhiv za celokupno lekarstvo, 1964, Volume: 92

    Topics: Antipyrine; Arthritis; Arthritis, Rheumatoid; Drug Combinations; Phenylbutazone; Propylamines; Rheum

1964
Edaravone inhibits rheumatoid synovial cell proliferation and migration.
    Free radical research, 2006, Volume: 40, Issue:2

    Topics: Aged; Antipyrine; Arthritis, Rheumatoid; Cell Movement; Cell Proliferation; Edaravone; Female; Free

2006
Specific modification of peptide-bound citrulline residues.
    Analytical biochemistry, 2006, May-01, Volume: 352, Issue:1

    Topics: Antipyrine; Arthritis, Rheumatoid; Chromatography, Liquid; Citrulline; Diacetyl; Magnetic Resonance

2006
Edaravone inhibits the disease activity in rheumatoid arthritis.
    Journal of clinical pharmacy and therapeutics, 2006, Volume: 31, Issue:2

    Topics: Antipyrine; Arthritis, Rheumatoid; C-Reactive Protein; Edaravone; Free Radical Scavengers; Humans; M

2006
Letter: Vitamin D deficiency in rheumatoid arthritis.
    British medical journal, 1975, Jan-11, Volume: 1, Issue:5949

    Topics: Antipyrine; Arthritis, Rheumatoid; Humans; Quinine; Vitamin D Deficiency

1975
[Testing of the antiphlogistic effect of antirheumatic drugs].
    Munchener medizinische Wochenschrift (1950), 1966, Oct-14, Volume: 108, Issue:41

    Topics: Antipyrine; Arthritis, Rheumatoid; Drug Synergism; Erythema; Humans; Injections, Intramuscular; Niac

1966
[Considerations on the use of aminophenazone and aminopropylon in equimolecular association in rheumatology].
    Minerva medica, 1968, Jan-13, Volume: 59, Issue:3

    Topics: Adolescent; Adult; Aged; Aminopyrine; Antipyrine; Arthritis, Infectious; Arthritis, Rheumatoid; Fema

1968
[New anti-inflammatory analgesic in rheumatoid arthritis].
    Revista espanola de reumatismo y enfermedades osteoarticulares, 1968, Volume: 12, Issue:8

    Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Antipyrine; Arthritis, Rheumatoid; Female; Humans

1968