antipyrine has been researched along with Anterior Choroidal Artery Infarction in 55 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One should consider the diagnosis of drug-induced vasospasm in patients with cerebral infarction and a history of excessive use of sumatriptan and Midrin." | 8.80 | Reversible segmental cerebral arterial vasospasm and cerebral infarction: possible association with excessive use of sumatriptan and Midrin. ( Biller, J; Malkoff, MD; Meschia, JF, 1998) |
| "To investigate the protective effect of edaravone and danshensu conjugate (IM-009) on focal cerebral ischemia-reperfusion injury in rats and its underlying mechanisms." | 7.81 | [Protective effect of novel edaravone and danshensu conjugate on focal cerebral ischemia-reperfusion injury in rats and its underlying mechanism]. ( Chen, H; Hou, S; Zhang, S, 2015) |
| "Edaravone attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia." | 7.80 | Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia. ( Johshita, H; Miyazaki, H; Okamura, K; Shiokawa, Y; Tsubokawa, T, 2014) |
| "Edaravone is a free radical scavenger that protects the adjacent cortex during cerebral infarction." | 7.79 | Effects of edaravone, a free radical scavenger, on photochemically induced cerebral infarction in a rat hemiplegic model. ( Harada, K; Ikeda, S; Kamikawa, Y; Ohwatashi, A, 2013) |
| "Edaravone is a novel free radical scavenger that is clinically employed in patients with acute cerebral infarction." | 7.78 | Treatment with edaravone attenuates ischemic brain injury and inhibits neurogenesis in the subventricular zone of adult rats after focal cerebral ischemia and reperfusion injury. ( Chen, X; Gao, M; Lei, S; Li, L; Li, W; Li, X; Liu, Y; Lu, H; Wang, N; Zhang, P; Zheng, J, 2012) |
| "Edaravone, a potent free radical scavenger, is clinically used for the treatment of cerebral infarction in Japan." | 7.75 | The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells. ( Arimura, N; Biswas, KK; Hashiguchi, T; Ito, T; Iwata, M; Kawahara, K; Kikuchi, K; Kuramoto, T; Maruyama, I; Matsuda, F; Miura, N; Morimoto, Y; Nakayama, K; Nawa, Y; Oyama, Y; Shigemori, M; Tajima, Y; Takenouchi, K; Tancharoen, S; Yoshida, Y, 2009) |
| "Prophylactic administration of edaravone exerted a significant protective effect against postoperative neurologic dysfunction after antegrade selective cerebral perfusion in a canine model with old cerebral infarction." | 7.74 | Effect of prophylactically administered edaravone during antegrade cerebral perfusion in a canine model of old cerebral infarction. ( Akuzawa, S; Bashar, AH; Fujie, M; Kazui, T; Ohishi, K; Ohkura, K; Suzuki, K; Suzuki, T; Terada, H; Washiyama, N; Yamamoto, S; Yamashita, K, 2007) |
| "A 60-year-old male with cerebral infarction was admitted to our hospital and treated with edaravone." | 7.74 | A case report of acute renal failure and fulminant hepatitis associated with edaravone administration in a cerebral infarction patient. ( Abe, M; Kaizu, K; Matsumoto, K, 2007) |
| " With use of this system we studied whether human serum obtained from patients with acute cerebral infarction (n = 16) would have a proliferative effect on vessels and whether an administration of a free radical scavenger, edaravone, with or without amlodipine would elicit antiproliferative effects." | 7.72 | [Alterations of antiproliferative effects of serum obtained from patients with acute cerebral infarction treated with a radical scavenger, edaravone, with or without amlodipine using an in vitro cultured basilar artery smooth muscle cells]. ( Echizen, H; Hiraga, M; Ida, T; Kobayashi, T; Oishi, K; Uchida, MK; Yamaguchi, T, 2004) |
| "We investigated whether or not a combination of the selective thrombin inhibitor, argatroban, and the free radical scavenger, edaravone (MCI-186), ameliorates postischemic hypoperfusion and decreases mortality after 15 min of forebrain ischemia in the gerbil." | 7.71 | Combined argatroban and edaravone caused additive neuroprotection against 15 min of forebrain ischemia in gerbils. ( Jin, YJ; Mima, T; Park, KC; Raicu, V; Shimizu, K, 2002) |
| "It is hypothesized that cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) is induced by free radicals released from a subarachnoid clot." | 6.74 | Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage. ( Asano, K; Munakata, A; Nakano, T; Naraoka, M; Ohkuma, H; Shimamura, N, 2009) |
| "Edaravone was administered to 27 randomly selected patients (GIa, n = 13; GIIa, n = 14) and its efficacy was studied by comparing their plasma OxLDL, S-100B, and MnSOD levels to those in patients without edaravone (GIb, n = 11, GIIb, n = 13)." | 6.71 | Inhibition of brain damage by edaravone, a free radical scavenger, can be monitored by plasma biomarkers that detect oxidative and astrocyte damage in patients with acute cerebral infarction. ( Harada, M; Itabe, H; Kitazato, KT; Matsuzaki, K; Nagahiro, S; Suzue, A; Uno, M, 2005) |
| "One should consider the diagnosis of drug-induced vasospasm in patients with cerebral infarction and a history of excessive use of sumatriptan and Midrin." | 4.80 | Reversible segmental cerebral arterial vasospasm and cerebral infarction: possible association with excessive use of sumatriptan and Midrin. ( Biller, J; Malkoff, MD; Meschia, JF, 1998) |
| "To investigate the protective effect of edaravone and danshensu conjugate (IM-009) on focal cerebral ischemia-reperfusion injury in rats and its underlying mechanisms." | 3.81 | [Protective effect of novel edaravone and danshensu conjugate on focal cerebral ischemia-reperfusion injury in rats and its underlying mechanism]. ( Chen, H; Hou, S; Zhang, S, 2015) |
| "Edaravone attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia." | 3.80 | Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia. ( Johshita, H; Miyazaki, H; Okamura, K; Shiokawa, Y; Tsubokawa, T, 2014) |
| "Edaravone is a free radical scavenger that protects the adjacent cortex during cerebral infarction." | 3.79 | Effects of edaravone, a free radical scavenger, on photochemically induced cerebral infarction in a rat hemiplegic model. ( Harada, K; Ikeda, S; Kamikawa, Y; Ohwatashi, A, 2013) |
| "Edaravone is a novel free radical scavenger that is clinically employed in patients with acute cerebral infarction." | 3.78 | Treatment with edaravone attenuates ischemic brain injury and inhibits neurogenesis in the subventricular zone of adult rats after focal cerebral ischemia and reperfusion injury. ( Chen, X; Gao, M; Lei, S; Li, L; Li, W; Li, X; Liu, Y; Lu, H; Wang, N; Zhang, P; Zheng, J, 2012) |
| "To clarify the relationship between the gain in functional recovery (rehabilitation gain) and the total amount of edaravone used for acute-phase therapy for cerebral infarction at a convalescent rehabilitation hospital." | 3.76 | Does functional outcome in acute ischaemic stroke patients correlate with the amount of free-radical scavenger treatment? A retrospective study of edaravone therapy. ( Katayama, M; Shimizu, H; Unno, Y, 2010) |
| "Edaravone, a potent free radical scavenger, is clinically used for the treatment of cerebral infarction in Japan." | 3.75 | The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells. ( Arimura, N; Biswas, KK; Hashiguchi, T; Ito, T; Iwata, M; Kawahara, K; Kikuchi, K; Kuramoto, T; Maruyama, I; Matsuda, F; Miura, N; Morimoto, Y; Nakayama, K; Nawa, Y; Oyama, Y; Shigemori, M; Tajima, Y; Takenouchi, K; Tancharoen, S; Yoshida, Y, 2009) |
| "Prophylactic administration of edaravone exerted a significant protective effect against postoperative neurologic dysfunction after antegrade selective cerebral perfusion in a canine model with old cerebral infarction." | 3.74 | Effect of prophylactically administered edaravone during antegrade cerebral perfusion in a canine model of old cerebral infarction. ( Akuzawa, S; Bashar, AH; Fujie, M; Kazui, T; Ohishi, K; Ohkura, K; Suzuki, K; Suzuki, T; Terada, H; Washiyama, N; Yamamoto, S; Yamashita, K, 2007) |
| "A 60-year-old male with cerebral infarction was admitted to our hospital and treated with edaravone." | 3.74 | A case report of acute renal failure and fulminant hepatitis associated with edaravone administration in a cerebral infarction patient. ( Abe, M; Kaizu, K; Matsumoto, K, 2007) |
| " With use of this system we studied whether human serum obtained from patients with acute cerebral infarction (n = 16) would have a proliferative effect on vessels and whether an administration of a free radical scavenger, edaravone, with or without amlodipine would elicit antiproliferative effects." | 3.72 | [Alterations of antiproliferative effects of serum obtained from patients with acute cerebral infarction treated with a radical scavenger, edaravone, with or without amlodipine using an in vitro cultured basilar artery smooth muscle cells]. ( Echizen, H; Hiraga, M; Ida, T; Kobayashi, T; Oishi, K; Uchida, MK; Yamaguchi, T, 2004) |
| "We investigated whether or not a combination of the selective thrombin inhibitor, argatroban, and the free radical scavenger, edaravone (MCI-186), ameliorates postischemic hypoperfusion and decreases mortality after 15 min of forebrain ischemia in the gerbil." | 3.71 | Combined argatroban and edaravone caused additive neuroprotection against 15 min of forebrain ischemia in gerbils. ( Jin, YJ; Mima, T; Park, KC; Raicu, V; Shimizu, K, 2002) |
| "It is hypothesized that cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) is induced by free radicals released from a subarachnoid clot." | 2.74 | Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage. ( Asano, K; Munakata, A; Nakano, T; Naraoka, M; Ohkuma, H; Shimamura, N, 2009) |
| "Edaravone was infused at a dose of 30 mg, twice a day, for 14 days." | 2.71 | Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters. ( , 2003) |
| "Edaravone was associated with delayed evolution of infarcts and edema in patients with severe carotid-territorial stroke and decreased mortality during the acute stage." | 2.71 | Free radical scavenger, edaravone, in stroke with internal carotid artery occlusion. ( Arihiro, S; Fujii, K; Ibayashi, S; Iida, M; Kamouchi, M; Nakane, H; Okada, Y; Toyoda, K, 2004) |
| "Pretreatment with edaravone can prevent development of cognitive impairment after CEA." | 2.71 | Effects of the free radical scavenger, edaravone, on the development of postoperative cognitive impairment in patients undergoing carotid endarterectomy. ( Endo, H; Fukuda, T; Inoue, T; Kobayashi, M; Ogasawara, K; Ogawa, A; Terasaki, K; Yamadate, K; Yoshida, K, 2005) |
| "Edaravone was administered to 27 randomly selected patients (GIa, n = 13; GIIa, n = 14) and its efficacy was studied by comparing their plasma OxLDL, S-100B, and MnSOD levels to those in patients without edaravone (GIb, n = 11, GIIb, n = 13)." | 2.71 | Inhibition of brain damage by edaravone, a free radical scavenger, can be monitored by plasma biomarkers that detect oxidative and astrocyte damage in patients with acute cerebral infarction. ( Harada, M; Itabe, H; Kitazato, KT; Matsuzaki, K; Nagahiro, S; Suzue, A; Uno, M, 2005) |
| "Edaravone was treated twice via tail vein; after MCA occlusion and after reperfusion." | 1.43 | A free radical scavenger edaravone suppresses systemic inflammatory responses in a rat transient focal ischemia model. ( Arai, K; Fujiwara, N; Lee, BJ; Lo, EH; Mandeville, ET; Pham, LD; Som, AT, 2016) |
| "He had been treated for lung cancer by chemotherapy and irradiation 3 years earlier." | 1.40 | [Case of cardiac tamponade during the treatment of acute cerebral infarction]. ( Nagasawa, H; Ono, H; Tanaka, H; Yamakawa, T, 2014) |
| "On day after discharge, he developed cerebral infarction and showed persistence of multiple left ventricular thrombi." | 1.40 | Multiple left ventricular thrombi in a patient with dilated cardiomyopathy and cerebral infarction: a case report. ( Mine, T; Miyake, H; Sato, I, 2014) |
| "Mice subjected to 2-h filamental middle cerebral artery occlusion were treated with NBO (95% O2, during the ischemia) alone, with edaravone (1." | 1.35 | Combination effects of normobaric hyperoxia and edaravone on focal cerebral ischemia-induced neuronal damage in mice. ( Hara, H; Iwama, T; Nonaka, Y; Shimazawa, M; Yoshimura, S, 2008) |
| "Cerebral ischemia was induced in rats by injecting 150 mug of sodium laurate into the left internal carotid artery on day 1." | 1.35 | Wide therapeutic time window for Rho-kinase inhibition therapy in ischemic brain damage in a rat cerebral thrombosis model. ( Asano, T; Hitomi, A; Ikegaki, I; Satoh, S; Seto, M; Toshima, Y, 2008) |
| "In in vitro models of cerebral ischemia, exposure to hydrogen peroxide or glutamate induced cell death with overactivation of PARP, and treatment with DR2313 reduced excessive formation of poly(ADP-ribose) and cell death." | 1.33 | A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats. ( Hasegawa, T; Ishikawa, M; Kakui, N; Nakajima, H; Ohkuma, K, 2005) |
| "Edaravone-treated animals showed significantly improved neurological outcome." | 1.33 | Anti-apoptotic and neuroprotective effects of edaravone following transient focal ischemia in rats. ( Amemiya, S; Inaba, T; Kamiya, T; Katayama, Y; Kato, K; Nito, C; Shimazaki, K; Ueda, M, 2005) |
| "Cerebral ischemia was mechanically induced by 2-hour occlusion of the left middle cerebral artery (MCA) using an intraluminal filament followed by 24-hour reperfusion." | 1.33 | Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats. ( Hong, KW; Lee, JH; Lee, WS; Park, SY, 2005) |
| "Cerebral infarct volume and cerebral edema were measured by high-contrast silver infarct staining (SIS)." | 1.31 | Early effects of acid-base management during hypothermia on cerebral infarct volume, edema, and cerebral blood flow in acute focal cerebral ischemia in rats. ( Frietsch, T; Georgiadis, D; Kollmar, R; Kuschinsky, W; Schäbitz, WR; Schwab, S; Waschke, KF, 2002) |
| "The volume of cerebral infarction, induced by 2-h occlusion and subsequent 2-h reperfusion of MCA in Fisher-344 rats, was evaluated." | 1.30 | Involvement of free radicals in cerebral vascular reperfusion injury evaluated in a transient focal cerebral ischemia model of rat. ( Iwai, T; Nakashima, M; Niwa, M; Uematsu, T, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.64) | 18.7374 |
| 1990's | 4 (7.27) | 18.2507 |
| 2000's | 31 (56.36) | 29.6817 |
| 2010's | 18 (32.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikeda, S | 1 |
| Harada, K | 1 |
| Ohwatashi, A | 1 |
| Kamikawa, Y | 1 |
| Okamura, K | 1 |
| Tsubokawa, T | 1 |
| Johshita, H | 1 |
| Miyazaki, H | 1 |
| Shiokawa, Y | 1 |
| Nagasawa, H | 1 |
| Ono, H | 1 |
| Tanaka, H | 1 |
| Yamakawa, T | 1 |
| Yamamoto, Y | 2 |
| Mine, T | 1 |
| Sato, I | 1 |
| Miyake, H | 1 |
| Nishihira, T | 1 |
| Suzuki, K | 2 |
| Takekawa, H | 1 |
| Nakamura, T | 1 |
| Iwasaki, A | 1 |
| Hirata, K | 1 |
| Zhang, S | 1 |
| Hou, S | 1 |
| Chen, H | 1 |
| Fujiwara, N | 1 |
| Som, AT | 1 |
| Pham, LD | 1 |
| Lee, BJ | 1 |
| Mandeville, ET | 1 |
| Lo, EH | 1 |
| Arai, K | 1 |
| Nonaka, Y | 1 |
| Shimazawa, M | 1 |
| Yoshimura, S | 1 |
| Iwama, T | 1 |
| Hara, H | 1 |
| Osaka, H | 1 |
| Okazaki, S | 1 |
| Higashi, Y | 1 |
| Munakata, A | 1 |
| Ohkuma, H | 1 |
| Nakano, T | 1 |
| Shimamura, N | 1 |
| Asano, K | 1 |
| Naraoka, M | 1 |
| Kikuchi, K | 1 |
| Kawahara, K | 1 |
| Tancharoen, S | 1 |
| Matsuda, F | 1 |
| Morimoto, Y | 1 |
| Ito, T | 1 |
| Biswas, KK | 1 |
| Takenouchi, K | 1 |
| Miura, N | 1 |
| Oyama, Y | 1 |
| Nawa, Y | 1 |
| Arimura, N | 1 |
| Iwata, M | 1 |
| Tajima, Y | 1 |
| Kuramoto, T | 1 |
| Nakayama, K | 1 |
| Shigemori, M | 1 |
| Yoshida, Y | 1 |
| Hashiguchi, T | 1 |
| Maruyama, I | 1 |
| Woitzik, J | 1 |
| Lassel, E | 1 |
| Hecht, N | 1 |
| Schneider, UC | 1 |
| Schroeck, H | 1 |
| Vajkoczy, P | 1 |
| Graf, R | 1 |
| Yamasaki, H | 1 |
| Matsubara, S | 1 |
| Sasaki, I | 1 |
| Nagahiro, S | 2 |
| Guo, Q | 1 |
| Wang, G | 1 |
| Namura, S | 1 |
| Unno, Y | 1 |
| Katayama, M | 1 |
| Shimizu, H | 1 |
| Shibata, K | 1 |
| Hashimoto, T | 1 |
| Nobe, K | 1 |
| Hasumi, K | 1 |
| Honda, K | 1 |
| Liu, N | 1 |
| Shang, J | 1 |
| Tian, F | 1 |
| Nishi, H | 1 |
| Abe, K | 5 |
| Kamiya, T | 2 |
| Ohara, T | 1 |
| Nagakane, Y | 1 |
| Tanaka, E | 1 |
| Morii, F | 1 |
| Koizumi, T | 1 |
| Zhang, P | 1 |
| Li, W | 1 |
| Li, L | 1 |
| Wang, N | 1 |
| Li, X | 1 |
| Gao, M | 1 |
| Zheng, J | 1 |
| Lei, S | 1 |
| Chen, X | 1 |
| Lu, H | 1 |
| Liu, Y | 1 |
| Lu, RY | 1 |
| Luo, DF | 1 |
| Xiao, SH | 1 |
| Yang, LH | 1 |
| Zhao, J | 1 |
| Ji, EN | 1 |
| Tao, EX | 1 |
| Xing, YG | 1 |
| Zhu, FY | 1 |
| Luan, P | 1 |
| Liu, J | 1 |
| Shinohara, Y | 1 |
| Inoue, S | 1 |
| Kollmar, R | 1 |
| Frietsch, T | 1 |
| Georgiadis, D | 1 |
| Schäbitz, WR | 1 |
| Waschke, KF | 1 |
| Kuschinsky, W | 1 |
| Schwab, S | 1 |
| Otori, T | 1 |
| Greenberg, JH | 1 |
| Welsh, FA | 1 |
| Takabatake, Y | 1 |
| Uno, E | 1 |
| Wakamatsu, K | 1 |
| Yamazaki, N | 1 |
| Hashimoto, N | 1 |
| Tsuchiya, Y | 1 |
| Yamaguchi, T | 1 |
| Ida, T | 1 |
| Kobayashi, T | 1 |
| Hiraga, M | 1 |
| Oishi, K | 1 |
| Uchida, MK | 1 |
| Echizen, H | 1 |
| Toyoda, K | 1 |
| Fujii, K | 1 |
| Kamouchi, M | 1 |
| Nakane, H | 1 |
| Arihiro, S | 1 |
| Okada, Y | 1 |
| Ibayashi, S | 1 |
| Iida, M | 1 |
| Nakajima, H | 1 |
| Kakui, N | 1 |
| Ohkuma, K | 1 |
| Ishikawa, M | 1 |
| Hasegawa, T | 1 |
| Fushimi, H | 1 |
| Amemiya, S | 1 |
| Nito, C | 1 |
| Inaba, T | 1 |
| Kato, K | 1 |
| Ueda, M | 1 |
| Shimazaki, K | 1 |
| Katayama, Y | 1 |
| Lee, JH | 1 |
| Park, SY | 1 |
| Lee, WS | 1 |
| Hong, KW | 1 |
| Ogasawara, K | 1 |
| Yamadate, K | 1 |
| Kobayashi, M | 1 |
| Endo, H | 1 |
| Fukuda, T | 1 |
| Yoshida, K | 1 |
| Terasaki, K | 1 |
| Inoue, T | 1 |
| Ogawa, A | 1 |
| Uno, M | 1 |
| Kitazato, KT | 1 |
| Suzue, A | 1 |
| Matsuzaki, K | 1 |
| Harada, M | 1 |
| Itabe, H | 1 |
| Wen, J | 1 |
| Watanabe, K | 1 |
| Ma, M | 1 |
| Yamaguchi, K | 1 |
| Tachikawa, H | 1 |
| Kodama, M | 1 |
| Aizawa, Y | 1 |
| Suzuki, T | 1 |
| Kazui, T | 1 |
| Yamamoto, S | 1 |
| Washiyama, N | 1 |
| Ohkura, K | 1 |
| Ohishi, K | 1 |
| Bashar, AH | 1 |
| Yamashita, K | 1 |
| Terada, H | 1 |
| Akuzawa, S | 1 |
| Fujie, M | 1 |
| Abe, M | 1 |
| Kaizu, K | 1 |
| Matsumoto, K | 1 |
| Niyaz, M | 1 |
| Numakawa, T | 1 |
| Matsuki, Y | 1 |
| Kumamaru, E | 1 |
| Adachi, N | 1 |
| Kitazawa, H | 1 |
| Kunugi, H | 1 |
| Kudo, M | 1 |
| Satoh, S | 1 |
| Toshima, Y | 1 |
| Hitomi, A | 1 |
| Ikegaki, I | 1 |
| Seto, M | 1 |
| Asano, T | 1 |
| Le Poncin-Lafitte, M | 1 |
| Grosdemouge, C | 1 |
| Roy-Billon, C | 1 |
| Duterte, D | 1 |
| Rapin, JR | 1 |
| Wittlich, F | 1 |
| Kohno, K | 1 |
| Mies, G | 1 |
| Norris, DG | 1 |
| Hoehn-Berlage, M | 1 |
| Grundl, PD | 1 |
| Biagas, KV | 1 |
| Kochanek, PM | 1 |
| Schiding, JK | 1 |
| Barmada, MA | 1 |
| Nemoto, EM | 1 |
| Meschia, JF | 1 |
| Malkoff, MD | 1 |
| Biller, J | 1 |
| Nakashima, M | 1 |
| Niwa, M | 1 |
| Iwai, T | 1 |
| Uematsu, T | 1 |
| MacGregor, DG | 1 |
| Carswell, HV | 1 |
| Graham, DI | 1 |
| McCulloch, J | 1 |
| Macrae, IM | 1 |
| Rossberg, MI | 1 |
| Murphy, SJ | 1 |
| Traystman, RJ | 1 |
| Hurn, PD | 2 |
| Vannucci, SJ | 1 |
| Willing, LB | 1 |
| Goto, S | 1 |
| Alkayed, NJ | 1 |
| Brucklacher, RM | 1 |
| Wood, TL | 1 |
| Towfighi, J | 1 |
| Simpson, IA | 1 |
| Kimura, T | 1 |
| Sako, K | 1 |
| Tanaka, K | 1 |
| Kusakabe, M | 1 |
| Tanaka, T | 1 |
| Nakada, T | 1 |
| Jin, YJ | 1 |
| Mima, T | 1 |
| Raicu, V | 1 |
| Park, KC | 1 |
| Shimizu, K | 1 |
| Dietrich, WD | 1 |
| Busto, R | 1 |
| Ginsberg, MD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Nerve Growth Factor or Edaravone on Alcohol-induced Brain Injury[NCT03968042] | Phase 2 | 150 participants (Anticipated) | Interventional | 2019-06-30 | Recruiting | ||
| Multicenter Randomized Open-Label Comparison Study on the Efficacy and Safety of Argatroban Monotherapy With Argatroban-Edaravone Combination Therapy[NCT00153946] | Phase 4 | 814 participants (Actual) | Interventional | 2004-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for antipyrine and Anterior Choroidal Artery Infarction
| Article | Year |
|---|---|
[Concept, pathophysiology and treatment for branch atheromatous disease].
Topics: Antipyrine; Arginine; Cerebral Infarction; Cilostazol; Clopidogrel; Contraindications; Drug Therapy, | 2014 |
Edaravone for the treatment of acute cerebral infarction: role of endothelium-derived nitric oxide and oxidative stress.
Topics: Acute Disease; Antipyrine; Cerebral Infarction; Edaravone; Endothelium, Vascular; Free Radical Scave | 2009 |
[Future neuroprotective strategies in the post-thrombolysis era--neurovascular unit protection and vascular endothelial protection].
Topics: Amines; Animals; Antipyrine; Cerebral Infarction; Cyclohexanecarboxylic Acids; Edaravone; Endotheliu | 2011 |
[Concept of branch atheromatous disease (BAD) and its clinical significance].
Topics: Antipyrine; Arginine; Cerebral Infarction; Cilostazol; Drug Therapy, Combination; Edaravone; Humans; | 2010 |
[Gene therapy and neuroprotection for cerebral infarction].
Topics: Adenoviridae; Animals; Antipyrine; Cerebral Infarction; Cerebrovascular Circulation; Edaravone; Free | 2003 |
[Treatment of cerebral infarction patients with IGT].
Topics: Antidepressive Agents; Antipyrine; Atorvastatin; Cerebral Infarction; Edaravone; Free Radical Scaven | 2005 |
[Edaravone].
Topics: Antipyrine; Cerebral Infarction; Edaravone; Free Radical Scavengers; Humans | 2006 |
Reversible segmental cerebral arterial vasospasm and cerebral infarction: possible association with excessive use of sumatriptan and Midrin.
Topics: Acetaminophen; Adult; Antipyrine; Cerebral Infarction; Chloral Hydrate; Drug Combinations; Drug Ther | 1998 |
5 trials available for antipyrine and Anterior Choroidal Artery Infarction
| Article | Year |
|---|---|
Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage.
Topics: Antipyrine; Cerebral Infarction; Comorbidity; Edaravone; Female; Free Radical Scavengers; Humans; Ja | 2009 |
Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antipyrine; Cerebral Infarction; Double-Blind Method; | 2003 |
Free radical scavenger, edaravone, in stroke with internal carotid artery occlusion.
Topics: Aged; Antipyrine; Atrial Fibrillation; Brain Edema; Carotid Artery Thrombosis; Carotid Artery, Inter | 2004 |
Effects of the free radical scavenger, edaravone, on the development of postoperative cognitive impairment in patients undergoing carotid endarterectomy.
Topics: Aged; Antipyrine; Carotid Artery, Internal; Carotid Stenosis; Cerebral Infarction; Cerebrovascular C | 2005 |
Inhibition of brain damage by edaravone, a free radical scavenger, can be monitored by plasma biomarkers that detect oxidative and astrocyte damage in patients with acute cerebral infarction.
Topics: Adult; Aged; Aged, 80 and over; Antipyrine; Astrocytes; Biomarkers; Cerebral Infarction; Edaravone; | 2005 |
42 other studies available for antipyrine and Anterior Choroidal Artery Infarction
| Article | Year |
|---|---|
Effects of edaravone, a free radical scavenger, on photochemically induced cerebral infarction in a rat hemiplegic model.
Topics: Animals; Antipyrine; Cerebral Infarction; Edaravone; Free Radical Scavengers; Hemiplegia; Intracrani | 2013 |
Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia.
Topics: Animals; Antipyrine; Blood Glucose; Brain; Cerebral Hemorrhage; Cerebral Infarction; Edaravone; Free | 2014 |
[Case of cardiac tamponade during the treatment of acute cerebral infarction].
Topics: Acute Disease; Adenocarcinoma; Anterior Cerebral Artery; Antipyrine; Aspirin; Cardiac Tamponade; Cer | 2014 |
Multiple left ventricular thrombi in a patient with dilated cardiomyopathy and cerebral infarction: a case report.
Topics: Aged; Anticoagulants; Antipyrine; Cardiomyopathy, Dilated; Cerebral Infarction; Edaravone; Heart Dis | 2014 |
[Lateral medullary infarction presenting with truncal lateropulsion and decreased pain and temperature sensation below T10 sensory level].
Topics: Antipyrine; Arginine; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Edaravone; Free R | 2014 |
[Protective effect of novel edaravone and danshensu conjugate on focal cerebral ischemia-reperfusion injury
in rats and its underlying mechanism].
Topics: Animals; Antipyrine; Brain Edema; Brain Ischemia; Cerebral Infarction; Edaravone; Lactates; Malondia | 2015 |
A free radical scavenger edaravone suppresses systemic inflammatory responses in a rat transient focal ischemia model.
Topics: Animals; Antipyrine; Brain Edema; Cerebral Infarction; Cytokines; Edaravone; Free Radical Scavengers | 2016 |
Combination effects of normobaric hyperoxia and edaravone on focal cerebral ischemia-induced neuronal damage in mice.
Topics: Animals; Antipyrine; Blood Pressure; Cell Death; Cerebral Infarction; Disease Models, Animal; Edarav | 2008 |
[Outcome assessment in treatment of edaravone in childhood ischemic stroke].
Topics: Adolescent; Antipyrine; Cerebral Infarction; Child; Child, Preschool; Edaravone; Female; Free Radica | 2008 |
The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells.
Topics: Active Transport, Cell Nucleus; Animals; Antipyrine; Apoptosis; Butadienes; Cell Hypoxia; Cell Nucle | 2009 |
Ischemia independent lesion evolution during focal stroke in rats.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Autoradiography; | 2009 |
Retinal artery embolization during carotid angioplasty and carotid artery stenting: case report.
Topics: Aged; Angioplasty, Balloon; Anticoagulants; Antipyrine; Aspirin; Carotid Artery, External; Carotid S | 2009 |
Fenofibrate improves cerebral blood flow after middle cerebral artery occlusion in mice.
Topics: Animals; Antipyrine; Arterial Occlusive Diseases; Autoradiography; Brain Ischemia; Capillaries; Cere | 2010 |
Does functional outcome in acute ischaemic stroke patients correlate with the amount of free-radical scavenger treatment? A retrospective study of edaravone therapy.
Topics: Aged; Aged, 80 and over; Antipyrine; Cerebral Infarction; Dose-Response Relationship, Drug; Edaravon | 2010 |
Neuroprotective mechanisms of SMTP-7 in cerebral infarction model in mice.
Topics: Aldehydes; Animals; Antipyrine; Benzopyrans; Brain; Cerebral Infarction; Disease Models, Animal; Eda | 2011 |
In vivo optical imaging for evaluating the efficacy of edaravone after transient cerebral ischemia in mice.
Topics: Animals; Annexin A5; Antipyrine; Apoptosis; Autophagy; Blood-Brain Barrier; Blotting, Western; Cereb | 2011 |
Treatment with edaravone attenuates ischemic brain injury and inhibits neurogenesis in the subventricular zone of adult rats after focal cerebral ischemia and reperfusion injury.
Topics: Analysis of Variance; Animals; Antipyrine; Bromodeoxyuridine; Cerebral Infarction; Cerebral Ventricl | 2012 |
[Therapeutic time window for ischemic stroke].
Topics: Antipyrine; Cerebral Infarction; Edaravone; Fibrinolytic Agents; Free Radical Scavengers; Humans; Ti | 2011 |
Kallikrein gene transfer induces angiogenesis and further improves regional cerebral blood flow in the early period after cerebral ischemia/reperfusion in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Carbon Isotopes; Cerebral Infarction; | 2012 |
Cost-effectiveness analysis of the neuroprotective agent edaravone for noncardioembolic cerebral infarction.
Topics: Aged; Antipyrine; Cerebral Infarction; Computer Simulation; Cost Savings; Cost-Benefit Analysis; Dru | 2013 |
Early effects of acid-base management during hypothermia on cerebral infarct volume, edema, and cerebral blood flow in acute focal cerebral ischemia in rats.
Topics: Acid-Base Equilibrium; Animals; Antipyrine; Autoradiography; Brain Edema; Brain Ischemia; Cerebral I | 2002 |
Cortical spreading depression causes a long-lasting decrease in cerebral blood flow and induces tolerance to permanent focal ischemia in rat brain.
Topics: Adaptation, Physiological; Animals; Antipyrine; Autoradiography; Brain; Brain Ischemia; Cerebral Inf | 2003 |
[The clinical effect of combination therapy with edaravone and sodium ozagrel for acute cerebral infarction].
Topics: Aged; Antipyrine; Cerebral Infarction; Drug Therapy, Combination; Edaravone; Female; Fibrinolytic Ag | 2003 |
[Alterations of antiproliferative effects of serum obtained from patients with acute cerebral infarction treated with a radical scavenger, edaravone, with or without amlodipine using an in vitro cultured basilar artery smooth muscle cells].
Topics: Acute Disease; Aged; Amlodipine; Animals; Antioxidants; Antipyrine; Basilar Artery; Calcium Channel | 2004 |
A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats.
Topics: Animals; Antipyrine; Brain; Brain Ischemia; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured | 2005 |
Anti-apoptotic and neuroprotective effects of edaravone following transient focal ischemia in rats.
Topics: Animals; Antipyrine; Apoptosis; bcl-2-Associated X Protein; Brain Edema; Brain Ischemia; Cerebral Co | 2005 |
Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats.
Topics: Animals; Antioxidants; Antipyrine; Aspirin; bcl-2-Associated X Protein; Blotting, Western; Brain Ede | 2005 |
Edaravone inhibits JNK-c-Jun pathway and restores anti-oxidative defense after ischemia-reperfusion injury in aged rats.
Topics: Aging; Animals; Antioxidants; Antipyrine; Blotting, Western; Brain; Cerebral Infarction; Edaravone; | 2006 |
Effect of prophylactically administered edaravone during antegrade cerebral perfusion in a canine model of old cerebral infarction.
Topics: Analysis of Variance; Animals; Antipyrine; Blood Chemical Analysis; Cardiopulmonary Bypass; Cerebral | 2007 |
A case report of acute renal failure and fulminant hepatitis associated with edaravone administration in a cerebral infarction patient.
Topics: Acute Kidney Injury; Antipyrine; Cerebral Infarction; Disseminated Intravascular Coagulation; Edarav | 2007 |
MCI-186 prevents brain tissue from neuronal damage in cerebral infarction through the activation of intracellular signaling.
Topics: Animals; Animals, Newborn; Antipyrine; Brain Edema; Butadienes; Cell Death; Cells, Cultured; Cerebra | 2007 |
Wide therapeutic time window for Rho-kinase inhibition therapy in ischemic brain damage in a rat cerebral thrombosis model.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antipyrine; Blood Flow Velocity; Brain Ische | 2008 |
[Cerebral blood flow, metabolism and learning after a cerebral infarction in the rat (author's transl)].
Topics: Animals; Antipyrine; Avoidance Learning; Brain; Brain Edema; Cerebral Infarction; Cerebrovascular Ci | 1981 |
Quantitative measurement of regional blood flow with gadolinium diethylenetriaminepentaacetate bolus track NMR imaging in cerebral infarcts in rats: validation with the iodo[14C]antipyrine technique.
Topics: Animals; Antipyrine; Blood Pressure; Brain; Carbon Dioxide; Carbon Radioisotopes; Cerebral Infarctio | 1995 |
Early cerebrovascular response to head injury in immature and mature rats.
Topics: Aging; Animals; Antipyrine; Blood Pressure; Body Temperature; Body Water; Brain; Brain Chemistry; Ce | 1994 |
Involvement of free radicals in cerebral vascular reperfusion injury evaluated in a transient focal cerebral ischemia model of rat.
Topics: Animals; Antipyrine; Brain; Caudate Nucleus; Cerebral Infarction; Cyclic N-Oxides; Disease Models, A | 1999 |
Impaired cerebral autoregulation 24 h after induction of transient unilateral focal ischaemia in the rat.
Topics: Animals; Antipyrine; Blood Pressure; Brain; Carbon Radioisotopes; Cerebellum; Cerebral Cortex; Cereb | 2000 |
LY353381.HCl, a selective estrogen receptor modulator, and experimental stroke.
Topics: Animals; Antipyrine; Autoradiography; Brain Ischemia; Carbon Radioisotopes; Cerebral Infarction; Cer | 2000 |
Experimental stroke in the female diabetic, db/db, mouse.
Topics: Animals; Antipyrine; Autoradiography; Brain; Carbon Radioisotopes; Cerebral Infarction; Cerebrovascu | 2001 |
Effect of mild hypothermia on energy state recovery following transient forebrain ischemia in the gerbil.
Topics: Adenosine Triphosphate; Animals; Antipyrine; Astrocytes; Body Temperature; Cerebral Cortex; Cerebral | 2002 |
Combined argatroban and edaravone caused additive neuroprotection against 15 min of forebrain ischemia in gerbils.
Topics: Animals; Anticoagulants; Antipyrine; Arginine; Body Water; Brain Edema; Brain Ischemia; Cerebral Inf | 2002 |
Effect of the serotonin antagonist ketanserin on the hemodynamic and morphological consequences of thrombotic infarction.
Topics: Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Cerebral Infarction; Cerebrovascular Cir | 1989 |