antipyrine has been researched along with Anoxia, Brain in 9 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Excerpt | Relevance | Reference |
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"Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a free radical scavenger, reduces brain edema in patients with acute ischemic stroke." | 3.74 | Edaravone inhibits the expression of vascular endothelial growth factor in human astrocytes exposed to hypoxia. ( Imaizumi, T; Ishikawa, A; Matsumiya, T; Metoki, N; Satoh, K; Taima, K; Toki, T; Yamashita, K; Yoshida, H, 2007) |
"Pretreatment with edaravone can prevent development of cognitive impairment after CEA." | 2.71 | Effects of the free radical scavenger, edaravone, on the development of postoperative cognitive impairment in patients undergoing carotid endarterectomy. ( Endo, H; Fukuda, T; Inoue, T; Kobayashi, M; Ogasawara, K; Ogawa, A; Terasaki, K; Yamadate, K; Yoshida, K, 2005) |
"Edaravone treatment (3mg/kg, i." | 1.40 | A radical scavenger edaravone inhibits matrix metalloproteinase-9 upregulation and blood-brain barrier breakdown in a mouse model of prolonged cerebral hypoperfusion. ( Arai, K; Liang, AC; Maki, T; Miyamoto, N; Pham, LD, 2014) |
"Cerebral ischemia was mechanically induced by 2-hour occlusion of the left middle cerebral artery (MCA) using an intraluminal filament followed by 24-hour reperfusion." | 1.33 | Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats. ( Hong, KW; Lee, JH; Lee, WS; Park, SY, 2005) |
"During cerebral hypoxia-ischemia (unilateral common carotid artery ligation and hypoxia with 8% oxygen), blood flows to all regions of the ipsilateral cerebral hemisphere were not different from control at 10 and 20 min." | 1.28 | Regional cerebral blood flow during hypoxia-ischemia in the immature rat: comparison of iodoantipyrine and iodoamphetamine as radioactive tracers. ( Bryan, RM; Ringel, M; Vannucci, RC, 1991) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (22.22) | 18.7374 |
1990's | 2 (22.22) | 18.2507 |
2000's | 3 (33.33) | 29.6817 |
2010's | 2 (22.22) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Miyamoto, N | 1 |
Pham, LD | 1 |
Maki, T | 1 |
Liang, AC | 1 |
Arai, K | 1 |
Somekawa-Kondo, T | 1 |
Yamaguchi, K | 1 |
Ishitsuka, Y | 1 |
Ito, S | 1 |
Tanaka, K | 1 |
Irikura, M | 1 |
Moriuchi, H | 1 |
Takahama, K | 1 |
Ando, Y | 1 |
Yamazaki, T | 1 |
Irie, T | 1 |
Lee, JH | 1 |
Park, SY | 1 |
Lee, WS | 1 |
Hong, KW | 1 |
Ogasawara, K | 1 |
Yamadate, K | 1 |
Kobayashi, M | 1 |
Endo, H | 1 |
Fukuda, T | 1 |
Yoshida, K | 1 |
Terasaki, K | 1 |
Inoue, T | 1 |
Ogawa, A | 1 |
Ishikawa, A | 1 |
Yoshida, H | 1 |
Metoki, N | 1 |
Toki, T | 1 |
Imaizumi, T | 1 |
Matsumiya, T | 1 |
Yamashita, K | 1 |
Taima, K | 1 |
Satoh, K | 1 |
Fabricius, M | 1 |
Lauritzen, M | 1 |
Ringel, M | 1 |
Bryan, RM | 1 |
Vannucci, RC | 3 |
Lyons, DT | 2 |
Vasta, F | 2 |
1 trial available for antipyrine and Anoxia, Brain
Article | Year |
---|---|
Effects of the free radical scavenger, edaravone, on the development of postoperative cognitive impairment in patients undergoing carotid endarterectomy.
Topics: Aged; Antipyrine; Carotid Artery, Internal; Carotid Stenosis; Cerebral Infarction; Cerebrovascular C | 2005 |
8 other studies available for antipyrine and Anoxia, Brain
Article | Year |
---|---|
A radical scavenger edaravone inhibits matrix metalloproteinase-9 upregulation and blood-brain barrier breakdown in a mouse model of prolonged cerebral hypoperfusion.
Topics: Animals; Antipyrine; Blood-Brain Barrier; Carotid Artery, Common; Carotid Stenosis; Cell Death; Cell | 2014 |
Aminophylline, administered at usual doses for rodents in pharmacological studies, induces hippocampal neuronal cell injury under low tidal volume hypoxic conditions in guinea-pigs.
Topics: Aminophylline; Animals; Antipyrine; CA1 Region, Hippocampal; Creatine Kinase, BB Form; Disease Model | 2013 |
Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats.
Topics: Animals; Antioxidants; Antipyrine; Aspirin; bcl-2-Associated X Protein; Blotting, Western; Brain Ede | 2005 |
Edaravone inhibits the expression of vascular endothelial growth factor in human astrocytes exposed to hypoxia.
Topics: Antipyrine; Astrocytes; Blood-Brain Barrier; Brain Edema; Cell Nucleus; Cells, Cultured; Cerebral Ar | 2007 |
Laser-Doppler evaluation of rat brain microcirculation: comparison with the [14C]-iodoantipyrine method suggests discordance during cerebral blood flow increases.
Topics: Animals; Antipyrine; Carbon Radioisotopes; Cerebral Cortex; Cerebrovascular Circulation; Hypoxia, Br | 1996 |
Regional cerebral blood flow during hypoxia-ischemia in the immature rat: comparison of iodoantipyrine and iodoamphetamine as radioactive tracers.
Topics: Amphetamines; Animals; Antipyrine; Autoradiography; Brain; Brain Ischemia; Cerebrovascular Circulati | 1991 |
Regional cerebral blood flow during hypoxia-ischemia in immature rats.
Topics: Animals; Animals, Newborn; Antipyrine; Autoradiography; Brain; Brain Ischemia; Carbon Radioisotopes; | 1988 |
Autoradiographic determination of regional cerebral blood flow in the immature rat.
Topics: Animals; Antipyrine; Autoradiography; Brain Ischemia; Cerebrovascular Circulation; Hypoxia, Brain; R | 1987 |