antipyrine has been researched along with Anoxemia in 23 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the mechanism of the pulmonary injury in rats caused by chronic intermittent hypoxia (CIH) and to investigate the intervention effect of Edaravone." | 7.81 | [The pulmonary injury in rats caused by chronic intermittent hypoxia and the intervention effect of Edaravone]. ( Kou, Y; Tan, X; Wang, H; Xie, B; Zhang, J; Zhang, M, 2015) |
| "We studied antipyrine metabolism in rats with different resistance to hypoxia during adaptation to cold stress." | 7.71 | Urine antipyrine metabolites in rats with different resistance to hypoxia subjected to cold stress. ( Gichev, YP; Grek, OR; Guseva, EO; Sharapov, VI, 2001) |
| "Experiments in rats with different sensitivity to hypobaric hypoxia established bimodal distribution of antipyrine and isoniazide half-lives." | 7.68 | [The effect of acute hypoxia on antipyrine and isoniazid pharmacokinetics in rats with different resistances to oxygen deficiency]. ( Grek, OR; Kolpakov, MA; Sharapov, VI, 1993) |
| "Local cerebral blood flow (CBF) was measured in rats, using an autoradiographic technique with 14C-iodoantipyrine as diffusible tracer, in situations with low, normal and high flow rates (phenobarbital anesthesia, analgesia with 75% N2O, and hypoxia, respectively)." | 7.66 | Local versus regional cerebral blood flow in the rat at high (hypoxia) and low (phenobarbital anesthesia) flow rates. ( Abdul-Rahman, A; Dahlgren, N; Ingvar, M; Rehncrona, S; Siesjö, BK, 1979) |
| "To investigate the mechanism of the pulmonary injury in rats caused by chronic intermittent hypoxia (CIH) and to investigate the intervention effect of Edaravone." | 3.81 | [The pulmonary injury in rats caused by chronic intermittent hypoxia and the intervention effect of Edaravone]. ( Kou, Y; Tan, X; Wang, H; Xie, B; Zhang, J; Zhang, M, 2015) |
| "We studied antipyrine metabolism in rats with different resistance to hypoxia during adaptation to cold stress." | 3.71 | Urine antipyrine metabolites in rats with different resistance to hypoxia subjected to cold stress. ( Gichev, YP; Grek, OR; Guseva, EO; Sharapov, VI, 2001) |
| "Experiments in rats with different sensitivity to hypobaric hypoxia established bimodal distribution of antipyrine and isoniazide half-lives." | 3.68 | [The effect of acute hypoxia on antipyrine and isoniazid pharmacokinetics in rats with different resistances to oxygen deficiency]. ( Grek, OR; Kolpakov, MA; Sharapov, VI, 1993) |
| "Local cerebral blood flow (CBF) was measured in rats, using an autoradiographic technique with 14C-iodoantipyrine as diffusible tracer, in situations with low, normal and high flow rates (phenobarbital anesthesia, analgesia with 75% N2O, and hypoxia, respectively)." | 3.66 | Local versus regional cerebral blood flow in the rat at high (hypoxia) and low (phenobarbital anesthesia) flow rates. ( Abdul-Rahman, A; Dahlgren, N; Ingvar, M; Rehncrona, S; Siesjö, BK, 1979) |
| "Treatment with edaravone significantly increased the number of NSPCs and newly generated neurons in the subgranular zone (p < ." | 1.40 | Pre- and posttreatment with edaravone protects CA1 hippocampus and enhances neurogenesis in the subgranular zone of dentate gyrus after transient global cerebral ischemia in rats. ( Chen, X; Gao, M; He, X; Lei, S; Li, W; Li, X; Liu, Y; Lu, H; Qi, C; Wang, N; Wang, X; Zhang, J; Zhang, P; Zheng, J, 2014) |
| "In vivo, rat transient middle cerebral artery occlusion (MCAO) model was established." | 1.38 | Protective effects of MCI-186 on transplantation of bone marrow stromal cells in rat ischemic stroke model. ( Ding, XS; Gu, XS; Han, Q; Huang, H; Huang, HF; Liu, XF; Shen, LH; Wu, EB; Ye, M; Zhang, C, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (39.13) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lei, S | 1 |
| Zhang, P | 1 |
| Li, W | 1 |
| Gao, M | 1 |
| He, X | 1 |
| Zheng, J | 1 |
| Li, X | 1 |
| Wang, X | 1 |
| Wang, N | 1 |
| Zhang, J | 2 |
| Qi, C | 1 |
| Lu, H | 1 |
| Chen, X | 1 |
| Liu, Y | 1 |
| Kou, Y | 1 |
| Xie, B | 1 |
| Wang, H | 1 |
| Tan, X | 1 |
| Zhang, M | 1 |
| Kaur, C | 2 |
| Sivakumar, V | 2 |
| Yip, GW | 1 |
| Ling, EA | 2 |
| Li, JJ | 1 |
| Lu, J | 1 |
| Wu, CY | 1 |
| Martínez-Romero, R | 1 |
| Cañuelo, A | 1 |
| Martínez-Lara, E | 1 |
| Javier Oliver, F | 1 |
| Cárdenas, S | 1 |
| Siles, E | 1 |
| Shen, LH | 1 |
| Ye, M | 1 |
| Ding, XS | 1 |
| Han, Q | 1 |
| Zhang, C | 1 |
| Liu, XF | 1 |
| Huang, H | 1 |
| Wu, EB | 1 |
| Huang, HF | 1 |
| Gu, XS | 1 |
| Qi, X | 1 |
| Okuma, Y | 1 |
| Hosoi, T | 1 |
| Nomura, Y | 1 |
| Itoh, Y | 1 |
| Takaoka, R | 1 |
| Ohira, M | 1 |
| Abe, T | 1 |
| Tanahashi, N | 1 |
| Suzuki, N | 1 |
| Sharapov, VI | 4 |
| Kolpakov, MA | 1 |
| Grek, OR | 3 |
| Chen, JL | 1 |
| Wei, L | 1 |
| Bereczki, D | 1 |
| Hans, FJ | 1 |
| Otsuka, T | 1 |
| Acuff, V | 1 |
| Richardson, G | 1 |
| Patlak, C | 1 |
| Fenstermacher, J | 1 |
| Watanabe, Y | 1 |
| Kusuoka, H | 1 |
| Fukuchi, K | 1 |
| Fujiwara, T | 1 |
| Nishimura, T | 1 |
| Gichev, IuP | 1 |
| Guseva, EO | 2 |
| Grek, OP | 1 |
| Gichev, YP | 1 |
| Abdul-Rahman, A | 1 |
| Dahlgren, N | 1 |
| Ingvar, M | 1 |
| Rehncrona, S | 1 |
| Siesjö, BK | 1 |
| Walker, DW | 1 |
| Merkle, P | 1 |
| Bindewald, H | 1 |
| Breitig, D | 1 |
| Lampé, LG | 1 |
| Vojcek, L | 1 |
| Princzkel, E | 1 |
| Csömör, S | 1 |
| Sakuragawa, N | 1 |
| Matsui, A | 1 |
| Matsuzaka, T | 1 |
| Kono, Y | 1 |
| Ido, T | 1 |
| Ishiwata, K | 1 |
| Kawashima, K | 1 |
| Ochsenfahrt, H | 1 |
| Winne, D | 1 |
| Hechtman, HB | 1 |
| Weisel, RD | 1 |
| Vito, L | 1 |
| Ali, J | 1 |
| Berger, RL | 1 |
| Reynolds, ML | 2 |
| Young, M | 2 |
| Hopins, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Hemodynamics and Extravascular Lung Water in Acute Lung Injury: A Prospective Randomized Controlled Multicentered Trial of Goal Directed Treatment of EVLW Versus Standard Management for the Treatment of Acute Lung Injury[NCT00624650] | Phase 2 | 33 participants (Actual) | Interventional | 2008-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
23 other studies available for antipyrine and Anoxemia
| Article | Year |
|---|---|
Pre- and posttreatment with edaravone protects CA1 hippocampus and enhances neurogenesis in the subgranular zone of dentate gyrus after transient global cerebral ischemia in rats.
Topics: Animals; Animals, Newborn; Antipyrine; Apoptosis; CA1 Region, Hippocampal; Cell Death; Cells, Cultur | 2014 |
[The pulmonary injury in rats caused by chronic intermittent hypoxia and the intervention effect of Edaravone].
Topics: Angiotensin II; Animals; Antipyrine; Edaravone; Free Radical Scavengers; Hypoxia; Lung; Lung Injury; | 2015 |
Expression of syndecan-2 in the amoeboid microglial cells and its involvement in inflammation in the hypoxic developing brain.
Topics: Age Factors; Animals; Animals, Newborn; Antipyrine; Cell Movement; Cells, Cultured; Corpus Callosum; | 2009 |
Expression of angiotensin II and its receptors in the normal and hypoxic amoeboid microglial cells and murine BV-2 cells.
Topics: Angiotensin II; Animals; Animals, Newborn; Antibodies; Antipyrine; Cell Hypoxia; Cells, Cultured; Co | 2009 |
Poly(ADP-ribose) polymerase-1 modulation of in vivo response of brain hypoxia-inducible factor-1 to hypoxia/reoxygenation is mediated by nitric oxide and factor inhibiting HIF.
Topics: Analysis of Variance; Animals; Antipyrine; Brain; Disease Models, Animal; Edaravone; Enzyme Inhibito | 2009 |
Protective effects of MCI-186 on transplantation of bone marrow stromal cells in rat ischemic stroke model.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antipyrine; Brain; Brain Infarction; Brain-Derived | 2012 |
Edaravone protects against hypoxia/ischemia-induced endoplasmic reticulum dysfunction.
Topics: Animals; Antipyrine; Apoptosis; Brain Ischemia; Cells, Cultured; Edaravone; Endoplasmic Reticulum; F | 2004 |
Reactive oxygen species generated by mitochondrial injury in human brain microvessel endothelial cells.
Topics: Antipyrine; Brain; Brain Ischemia; Cerebrovascular Circulation; Edaravone; Endothelium, Vascular; Fr | 2006 |
[The effect of acute hypoxia on antipyrine and isoniazid pharmacokinetics in rats with different resistances to oxygen deficiency].
Topics: Acute Disease; Animals; Antipyrine; Atmosphere Exposure Chambers; Disease Susceptibility; Half-Life; | 1993 |
Virtually unaltered permeability-surface area products imply little capillary recruitment in brain with hypoxia.
Topics: 3-O-Methylglucose; Animals; Antipyrine; Autoradiography; Blood Flow Velocity; Blood-Brain Barrier; B | 1994 |
[Activity of liver monooxygenase system in rats with low and high resistance to hypoxia].
Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Cytochromes b5; Diazepam; Hypoxia; Male; Micros | 1996 |
Contribution of hypoxia to the development of cardiomyopathy in hamsters.
Topics: Animals; Antipyrine; Autoradiography; Cardiomyopathy, Dilated; Cricetinae; Hypoxia; Iodine Radioisot | 1997 |
[Antipyrine pharmacokinetics in rats with various resistance to hypoxia during cold stress].
Topics: Acute Disease; Animals; Antipyrine; Cold Temperature; Hypoxia; Male; Rats; Rats, Wistar; Species Spe | 1998 |
Urine antipyrine metabolites in rats with different resistance to hypoxia subjected to cold stress.
Topics: Adaptation, Physiological; Animals; Antipyrine; Cold Temperature; Hypoxia; Male; Rats; Rats, Wistar; | 2001 |
Local versus regional cerebral blood flow in the rat at high (hypoxia) and low (phenobarbital anesthesia) flow rates.
Topics: Anesthesia, General; Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Cerebrovascular Cir | 1979 |
Placental clearance of antipyrine and urea during hypoxia and adrenaline infusions in sheep [proceedings].
Topics: Animals; Antipyrine; Epinephrine; Female; Hypoxia; Placenta; Pregnancy; Sheep; Urea | 1977 |
[Functional and metabolic changes of the mucosa during the occlusion of the small bowel of the rat (author's transl)].
Topics: Alkaline Phosphatase; Animals; Antipyrine; Aspartate Aminotransferases; Biological Transport; Glucos | 1975 |
Blood flow redistribution during isocapnic hypoxia in foetal lamb.
Topics: Animals; Antipyrine; Blood Circulation; Carbon Dioxide; Female; Fetal Blood; Fetus; Hypoxia; Organ S | 1988 |
Enhanced glucose metabolism and impaired placental function in hypoxic pregnant rats.
Topics: Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Deoxyglucose; Female; Fluorine Radioisot | 1988 |
[Intestinal blood flow and absorption of drugs].
Topics: Aminopyrine; Aniline Compounds; Animals; Antipyrine; Biological Transport, Active; Carbon Isotopes; | 1968 |
The independence of pulmonary shunting and pulmonary edema.
Topics: Antipyrine; Cardiac Catheterization; Cardiac Surgical Procedures; Chemotherapy, Cancer, Regional Per | 1973 |
The transfer of free alpha-amino nitrogen across the placental membrane in the guinea-pig.
Topics: Amino Acids; Animals; Antimetabolites; Antipyrine; Biological Transport, Active; Cyanides; Female; G | 1971 |
The influence of blood flow and hypoxia on free alpha-amino nitrogen transfer across the placental membrane.
Topics: Amines; Animals; Antipyrine; Biological Transport, Active; Blood Pressure; Female; Fetus; Guinea Pig | 1970 |