antipyrine has been researched along with Angina Pectoris in 2 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Angina Pectoris: The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of hepatic drug-metabolizing enzyme activity for plasma propranolol and sotalol levels was investigated in 68 patients with hypertension or angina pectoris by comparing elimination rate with antipyrine kinetics and cytochrome P-450 content in the liver." | 3.66 | Plasma clearance of propranolol and sotalol and hepatic drug-metabolizing enzyme activity. ( Anttila, M; Järvensivu, P; Pelkonen, RO; Sotaniemi, EA; Sundquist, H, 1979) |
| "Verapamil elimination was also found to be impaired after chronic dosing as compared to single administration." | 1.27 | The effect of oral verapamil therapy on antipyrine clearance. ( Kokurina, EV; Metelitsa, VI; Piotrovskii, VK; Riabokon, OS; Rumiantsev, DO; Slastnikova, ID, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sotaniemi, EA | 1 |
| Anttila, M | 1 |
| Pelkonen, RO | 1 |
| Järvensivu, P | 1 |
| Sundquist, H | 1 |
| Rumiantsev, DO | 1 |
| Piotrovskii, VK | 1 |
| Riabokon, OS | 1 |
| Slastnikova, ID | 1 |
| Kokurina, EV | 1 |
| Metelitsa, VI | 1 |
2 other studies available for antipyrine and Angina Pectoris
| Article | Year |
|---|---|
Plasma clearance of propranolol and sotalol and hepatic drug-metabolizing enzyme activity.
Topics: Adult; Aged; Angina Pectoris; Antipyrine; Cytochrome P-450 Enzyme System; Female; Half-Life; Humans; | 1979 |
The effect of oral verapamil therapy on antipyrine clearance.
Topics: Administration, Oral; Adult; Angina Pectoris; Antipyrine; Half-Life; Humans; Kinetics; Male; Middle | 1986 |