antipyrine has been researched along with Allergy, Drug in 32 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Controlled oral challenge with nonsteroidal anti-inflammatory drugs (NSAIDs) is the only definite way to detect safe NSAIDs in patients with NSAID-induced anaphylactoid reactions." | 2.71 | Safety of the new selective cyclooxygenase type 2 inhibitors rofecoxib and celecoxib in patients with anaphylactoid reactions to nonsteroidal anti-inflammatory drugs. ( Conde, J; Delgado, J; Florido, JF; López-Pascual, E; Nieto, MA; Ortega, N; Quiralte, J; Sáenz de San Pedro, B, 2004) |
| "Propyphenazone is a sensitizing agent in susceptible individuals and can elicit IgE-mediated anaphylaxis." | 1.32 | IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone. ( Bohle, B; Ebner, C; Ebner, H; Ferreira, F; Grubmayr, K; Himly, M; Jahn-Schmid, B; Pittertschatscher, K, 2003) |
| "Antipyrine is a pyrazole derivative used extensively as a marker for hepatic drug metabolizing enzyme activity." | 1.28 | Allergic reaction to antipyrine, a marker of hepatic enzyme activity. ( McCrea, JB; Rocci, ML; Vlasses, PH, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (81.25) | 18.7374 |
| 1990's | 2 (6.25) | 18.2507 |
| 2000's | 3 (9.38) | 29.6817 |
| 2010's | 1 (3.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Steiner, M | 1 |
| Harrer, A | 1 |
| Lang, R | 1 |
| Schneider, M | 1 |
| Ferreira, T | 1 |
| Hawranek, T | 1 |
| Himly, M | 2 |
| Jahn-Schmid, B | 1 |
| Pittertschatscher, K | 1 |
| Bohle, B | 1 |
| Grubmayr, K | 1 |
| Ferreira, F | 1 |
| Ebner, H | 1 |
| Ebner, C | 1 |
| GHOSH, M | 1 |
| TERZANI, A | 1 |
| ROBINSON, HM | 1 |
| ICHIMARU, M | 1 |
| CHIBU, K | 1 |
| Quiralte, J | 1 |
| Delgado, J | 1 |
| Sáenz de San Pedro, B | 1 |
| López-Pascual, E | 1 |
| Nieto, MA | 1 |
| Ortega, N | 1 |
| Florido, JF | 1 |
| Conde, J | 1 |
| Patanè, S | 1 |
| Marte, F | 1 |
| Di Bella, G | 1 |
| Chiofalo, S | 1 |
| Currò, A | 1 |
| Coglitore, S | 1 |
| Landwehr, AJ | 1 |
| van Ketel, WG | 1 |
| Kadar, D | 1 |
| Kalow, W | 1 |
| Rubio-Martínez, A | 1 |
| García-Erce, JA | 1 |
| Salvador, C | 1 |
| Gómez-Arteta, E | 1 |
| Gimeno, JJ | 1 |
| Lochmann, O | 1 |
| Benes, J | 1 |
| Výmola, F | 1 |
| Pokorný, J | 1 |
| Perl, S | 1 |
| Tabarelli-Poplawski, S | 1 |
| Uehleke, H | 1 |
| Naess, K | 1 |
| Zhu, D | 1 |
| Becker, WM | 1 |
| Schulz, KH | 2 |
| Schubeler, K | 1 |
| Schlaak, M | 1 |
| McCrea, JB | 1 |
| Vlasses, PH | 1 |
| Rocci, ML | 1 |
| Brattig, NW | 1 |
| Diao, GJ | 1 |
| Berg, PA | 1 |
| Mihatsch, MJ | 1 |
| Kowalski, ML | 1 |
| Rozniecki, J | 1 |
| Ortuno, J | 1 |
| Botella, J | 1 |
| Trigger, DJ | 1 |
| Vesell, ES | 1 |
| Lüders, G | 1 |
| Monro, P | 1 |
| Kono, R | 1 |
| Kogoj, F | 1 |
| Samter, M | 1 |
| Beers, RF | 1 |
| Hartl, W | 1 |
| Puxeddu, A | 1 |
| Schmidt, P | 1 |
| Tritsch, H | 1 |
| Haustein, UF | 1 |
2 reviews available for antipyrine and Allergy, Drug
| Article | Year |
|---|---|
Recent progress in pharmacogenetics.
Topics: Adult; Aged; Alcohol Oxidoreductases; Antipyrine; Asian People; Child, Preschool; Cholinesterases; C | 1969 |
[Notes on fixed exanthemas].
Topics: Antipyrine; Bromine; Drug Hypersensitivity; Exanthema; Humans; Quinine | 1967 |
1 trial available for antipyrine and Allergy, Drug
| Article | Year |
|---|---|
Safety of the new selective cyclooxygenase type 2 inhibitors rofecoxib and celecoxib in patients with anaphylactoid reactions to nonsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Celecoxib; Cyclooxyge | 2004 |
29 other studies available for antipyrine and Allergy, Drug
| Article | Year |
|---|---|
Basophil activation test for investigation of IgE-mediated mechanisms in drug hypersensitivity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Basophils; Chromatography, Gel; Chromatography, | 2011 |
IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Drug Hypersensitivity; Enzym | 2003 |
Side-effect of dichloralphenazone.
Topics: Antipyrine; Chloral Hydrate; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; | 1963 |
[DAMAGE FROM THERAPY].
Topics: Adrenal Cortex Hormones; Anemia; Anemia, Aplastic; Anticoagulants; Antipyrine; Blood Group Incompati | 1963 |
DRUG ERUPTIONS.
Topics: Antipyrine; Barbiturates; Dermatitis, Contact; Drug Eruptions; Drug Hypersensitivity; Penicillins; P | 1964 |
[CASE OF AGRANULOCYTOSIS SHOWING A LEUKEMOID REACTION DURING THE RECOVERY PHASE].
Topics: Adrenal Cortex Hormones; Agranulocytosis; Antipyrine; Blood; Bone Marrow Examination; Chloramphenico | 1964 |
Acute myocardial infarction and Kounis syndrome.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Drug Hypersensitivity; Female; Flavoxate; | 2009 |
Delayed-type allergy to phenazone in a patient with erythema multiforme.
Topics: Adult; Antipyrine; Drug Hypersensitivity; Erythema Multiforme; Humans; Hypersensitivity, Delayed; Ma | 1982 |
Acute and latent leukopenic reaction to antipyrine.
Topics: Adult; Antipyrine; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; Leukopenia; Male; Tim | 1980 |
Autoimmune haemolytic anaemia induced by propyphenazone.
Topics: Adult; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Autoimmun | 1998 |
Observation of antibody activity against antibiotics in patients with atopic disease.
Topics: Analgesics; Anti-Bacterial Agents; Antibodies; Antipyrine; Asthma; Drug Hypersensitivity; Hemaggluti | 1978 |
Anaphylaxis after dichloralphenazone treatment.
Topics: Aged; Anaphylaxis; Antipyrine; Chloral Hydrate; Drug Combinations; Drug Hypersensitivity; Humans; Ma | 1977 |
Irreversible binding of 3-14C-antipyrine to hepatic protein in vivo and in metabolizing liver microsomes.
Topics: Agranulocytosis; Animals; Antipyrine; Drug Hypersensitivity; Hydroxylation; Liver; Male; Mice; Micro | 1977 |
[Phenazone. Anaphylactic shock after peroral administration. Danger of cross allergy?].
Topics: Administration, Oral; Antipyrine; Drug Hypersensitivity; Humans | 1977 |
Detection of IgE antibodies specific for 1-phenyl-2,3-dimethyl-3-pyrazoline-5-one by RAST: a serological diagnostic method for sensitivity to pyrazoline drugs.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Dipyrone; Drug Hypersensitivity; F | 1992 |
Allergic reaction to antipyrine, a marker of hepatic enzyme activity.
Topics: Acute Disease; Adult; Antipyrine; Drug Hypersensitivity; Humans; Liver; Male | 1989 |
The specificity of the lymphocyte transformation test in a patient with hypersensitivity reactions to pyrazolone compounds. A 10-week follow-up study before and after rechallenge.
Topics: Adult; Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Concanavalin A; Drug Hypers | 1988 |
Does pyrazolone-induced renal injury exist?
Topics: Acute Kidney Injury; Aged; Aminopyrine; Analgesics; Animals; Antipyrine; Cats; Dose-Response Relatio | 1986 |
[Development of aspirin tolerance in hypersensitive persons. I. Methods of development of tolerance, aspirin refraction time and cross tolerance to other drugs].
Topics: Antipyrine; Aspirin; Asthma; Cross Reactions; Drug Hypersensitivity; Drug Tolerance; Humans; Indomet | 1986 |
Recurrent acute renal failure induced by phenazone hypersensitivity.
Topics: Acute Kidney Injury; Adult; Anaphylaxis; Antipyrine; Biopsy; Blood Urea Nitrogen; Drug Hypersensitiv | 1973 |
Reaction after dichloralphenazone.
Topics: Antipyrine; Chloral Hydrate; Drug Hypersensitivity; Humans | 1967 |
[Pathogenesis of drug allergic reactions on the skin].
Topics: Antipyrine; Arteritis; Capillaries; Drug Eruptions; Drug Hypersensitivity; gamma-Globulins; Humans; | 1970 |
Iatrogenic encephalopathy.
Topics: Adult; Antipyrine; Brain Diseases; Chloral Hydrate; Chlorine; Chlorpromazine; Dermatitis, Exfoliativ | 1970 |
[Autopsy findings of anaphylactic shock and poisoning by the use of pyrazolone derivatives].
Topics: Adolescent; Adult; Aged; Aminopyrine; Anaphylaxis; Antipyrine; Autopsy; Child; Child, Preschool; Dru | 1973 |
Concerning the nature of intolerance to aspirin.
Topics: Aminopyrine; Antipyrine; Aspirin; Asthma; Chemoreceptor Cells; Drug Hypersensitivity; Edema; Histami | 1967 |
[On the problem of specificity of drug-allergic immune reactions by aminophenazone-containing antirheumatic aents].
Topics: Aminopyrine; Animals; Antigen-Antibody Reactions; Antipyrine; Complement Fixation Tests; Drug Hypers | 1966 |
[Fixed exanthema due to 3 different drugs with separate localization. Contribution to the problem of barbiturate allergy].
Topics: Antipyrine; Barbiturates; Drug Hypersensitivity; Exanthema; Female; Humans; Middle Aged; Phenobarbit | 1967 |
[Histological picture report No. 203. Lyell syndrome].
Topics: Antipyrine; Child, Preschool; Drug Hypersensitivity; Female; Humans; Infant; Penicillins; Phenolphth | 1968 |
[A fixed drug exanthema simulating the clinical picture of erythema exsudativum multiforme majus].
Topics: Adult; Aminopyrine; Antipyrine; Diagnosis, Differential; Drug Hypersensitivity; Exanthema; Female; H | 1965 |