antipyrine has been researched along with Alcoholism in 16 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic alcohol abuse, as well as liver disease, induces a decrease of hepatic GSH." | 5.29 | Effect of alcohol abuse and glutathione administration on the circulating levels of glutathione and on antipyrine metabolism in patients with alcoholic liver cirrhosis. ( De Girolamo, V; Del Vecchio Blanco, C; Disalvo, D; Guerriero, C; Loguercio, C; Piscopo, P, 1996) |
| "Chronic alcohol abuse, as well as liver disease, induces a decrease of hepatic GSH." | 1.29 | Effect of alcohol abuse and glutathione administration on the circulating levels of glutathione and on antipyrine metabolism in patients with alcoholic liver cirrhosis. ( De Girolamo, V; Del Vecchio Blanco, C; Disalvo, D; Guerriero, C; Loguercio, C; Piscopo, P, 1996) |
| "It is concluded that the groups with alcohol abuse who used hepatotoxic drugs showed a picture of cortical changes (wide transport sulci and clear-cut or high-grade cortical changes) and also of subcortical aberrations, expressed as an increased widening of the third ventricle." | 1.28 | Computed tomography of the brain, hepatotoxic drugs and high alcohol consumption in male alcoholic patients and a random sample from the general male population. ( Mützell, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (81.25) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gadeholt, G | 1 |
| Aarbakke, J | 1 |
| Dybing, E | 1 |
| Sjöblom, M | 1 |
| Mørland, J | 1 |
| Krampl, V | 1 |
| Kontskova, M | 1 |
| Kramplova, J | 1 |
| Goldberg, DM | 1 |
| Cushman, P | 1 |
| Barboriak, JJ | 1 |
| Liao, A | 1 |
| Hoffman, NE | 1 |
| Soto Alvarez, J | 1 |
| Alsar Ortiz, MJ | 1 |
| Loguercio, C | 1 |
| Piscopo, P | 1 |
| Guerriero, C | 1 |
| De Girolamo, V | 1 |
| Disalvo, D | 1 |
| Del Vecchio Blanco, C | 1 |
| Pirttiaho, HI | 1 |
| Sotaniemi, EA | 4 |
| Ahlqvist, J | 3 |
| Pitkänen, U | 1 |
| Pelkonen, RO | 3 |
| Harman, AW | 1 |
| Frewin, DB | 1 |
| Priestly, BG | 1 |
| Alexander, CB | 1 |
| Pirttiaho, H | 1 |
| Luoma, PV | 1 |
| Hartoma, TR | 1 |
| Pelkonen, O | 1 |
| Mützell, S | 1 |
| Debruyne, D | 1 |
| Gram, LF | 1 |
| Grollier, G | 1 |
| Camsonne, R | 1 |
| Agron, L | 1 |
| Dao, MT | 1 |
| Lacotte, J | 1 |
| Bigot, MC | 1 |
| Moulin, M | 1 |
| Niemelä, O | 1 |
| Risteli, L | 1 |
| Stenbäck, F | 1 |
| Lahtela, JT | 1 |
| Risteli, J | 1 |
| Vesell, ES | 1 |
| Murray, RM | 1 |
| Gundert-Remy, U | 1 |
| Marquardt, R | 1 |
| Andritsch, F | 1 |
| Weber, E | 1 |
1 review available for antipyrine and Alcoholism
| Article | Year |
|---|---|
The expanding role of microsomal enzyme induction, and its implications for clinical chemistry.
Topics: Acetaminophen; Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Electron Transport; E | 1980 |
15 other studies available for antipyrine and Alcoholism
| Article | Year |
|---|---|
Hepatic microsomal drug metabolism, glutamyl transferase activity and in vivo antipyrine half-life in rats chronically fed an ethanol diet, a control diet and a chow diet.
Topics: Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Diet; gamma-Glutamyltransferase; Hal | 1980 |
Influence of ethanol on the interaction between polychlorinated biphenyls and drug metabolism.
Topics: Alcoholism; Animals; Antipyrine; Drug Interactions; Ethanol; Humans; Kinetics; Male; Microsomes, Liv | 1980 |
Association between plasma high density lipoprotein cholesterol and antipyrine metabolism in alcoholics.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Antipyrine; Cholesterol; Cholesterol, HDL; Ethanol; Femal | 1982 |
[Oxidative hepatic metabolism in chronic alcoholics during the acute abstinence period: evaluation with antipyrine elimination].
Topics: Adult; Alcoholism; Antipyrine; Female; Humans; Liver; Male; Oxidation-Reduction; Saliva; Temperance | 1993 |
Effect of alcohol abuse and glutathione administration on the circulating levels of glutathione and on antipyrine metabolism in patients with alcoholic liver cirrhosis.
Topics: Adult; Aged; Alcoholism; Antipyrine; Female; Glutathione; Humans; Injections, Intravenous; Liver Cir | 1996 |
Liver size and indices of drug metabolism in alcoholics.
Topics: Adult; Aged; Alcoholism; Antipyrine; Cytochrome P-450 Enzyme System; Female; Humans; Liver; Male; Mi | 1978 |
Impairment of hepatic drug metabolism in alcoholics.
Topics: Adult; Aged; Alcoholism; Antipyrine; Half-Life; Humans; Kinetics; Liver; Liver Function Tests; Male; | 1979 |
Histological changes in the liver and indices of drug metabolism in alcoholics.
Topics: Adult; Aged; Alcoholism; Antipyrine; Cytochrome P-450 Enzyme System; Female; Half-Life; Humans; Kine | 1977 |
Serum zinc and serum copper and indices of drug metabolism in alcoholics.
Topics: Adult; Aged; Alcoholism; Antipyrine; Copper; Cytochrome P-450 Enzyme System; Female; Humans; Liver; | 1977 |
Computed tomography of the brain, hepatotoxic drugs and high alcohol consumption in male alcoholic patients and a random sample from the general male population.
Topics: Adult; Aged; Alcoholism; Analgesics; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Antipyrine; Aspiri | 1992 |
Quinidine disposition in relation to antipyrine elimination and debrisoquine phenotype in alcoholic patients with and without cirrhosis.
Topics: Adult; Aged; Alcoholism; Antipyrine; Chromatography, Liquid; Debrisoquin; Female; Half-Life; Humans; | 1989 |
Fibrotic process and drug metabolism in alcoholic liver disease.
Topics: Adult; Aged; Alcoholism; Antigens; Antipyrine; Basement Membrane; Collagen; Cytochrome P-450 Enzyme | 1986 |
Ethanol metabolism: regulation by genetic factors in normal volunteers under a controlled environment and the effect of chronic ethanol administration.
Topics: Adult; Alcohol Drinking; Alcoholism; Antipyrine; Environment; Ethanol; Female; Genetics, Medical; Ge | 1972 |
The origins of analgesic nephropathy.
Topics: Adult; Affective Symptoms; Aged; Alcoholism; Analgesics; Antipyrine; Aspirin; Codeine; Creatinine; F | 1973 |
[Induction of drug-catabolizing enzymes in chronic alcoholics].
Topics: Alcoholism; Antipyrine; Chronic Disease; Enzyme Induction; Humans; Microsomes, Liver; Pharmaceutical | 1974 |