antipyrine has been researched along with Alcohol Abuse in 16 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic alcohol abuse, as well as liver disease, induces a decrease of hepatic GSH." | 5.29 | Effect of alcohol abuse and glutathione administration on the circulating levels of glutathione and on antipyrine metabolism in patients with alcoholic liver cirrhosis. ( De Girolamo, V; Del Vecchio Blanco, C; Disalvo, D; Guerriero, C; Loguercio, C; Piscopo, P, 1996) |
| "Chronic alcohol abuse, as well as liver disease, induces a decrease of hepatic GSH." | 1.29 | Effect of alcohol abuse and glutathione administration on the circulating levels of glutathione and on antipyrine metabolism in patients with alcoholic liver cirrhosis. ( De Girolamo, V; Del Vecchio Blanco, C; Disalvo, D; Guerriero, C; Loguercio, C; Piscopo, P, 1996) |
| "It is concluded that the groups with alcohol abuse who used hepatotoxic drugs showed a picture of cortical changes (wide transport sulci and clear-cut or high-grade cortical changes) and also of subcortical aberrations, expressed as an increased widening of the third ventricle." | 1.28 | Computed tomography of the brain, hepatotoxic drugs and high alcohol consumption in male alcoholic patients and a random sample from the general male population. ( Mützell, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (81.25) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gadeholt, G | 1 |
| Aarbakke, J | 1 |
| Dybing, E | 1 |
| Sjöblom, M | 1 |
| Mørland, J | 1 |
| Krampl, V | 1 |
| Kontskova, M | 1 |
| Kramplova, J | 1 |
| Goldberg, DM | 1 |
| Cushman, P | 1 |
| Barboriak, JJ | 1 |
| Liao, A | 1 |
| Hoffman, NE | 1 |
| Soto Alvarez, J | 1 |
| Alsar Ortiz, MJ | 1 |
| Loguercio, C | 1 |
| Piscopo, P | 1 |
| Guerriero, C | 1 |
| De Girolamo, V | 1 |
| Disalvo, D | 1 |
| Del Vecchio Blanco, C | 1 |
| Pirttiaho, HI | 1 |
| Sotaniemi, EA | 4 |
| Ahlqvist, J | 3 |
| Pitkänen, U | 1 |
| Pelkonen, RO | 3 |
| Harman, AW | 1 |
| Frewin, DB | 1 |
| Priestly, BG | 1 |
| Alexander, CB | 1 |
| Pirttiaho, H | 1 |
| Luoma, PV | 1 |
| Hartoma, TR | 1 |
| Pelkonen, O | 1 |
| Mützell, S | 1 |
| Debruyne, D | 1 |
| Gram, LF | 1 |
| Grollier, G | 1 |
| Camsonne, R | 1 |
| Agron, L | 1 |
| Dao, MT | 1 |
| Lacotte, J | 1 |
| Bigot, MC | 1 |
| Moulin, M | 1 |
| Niemelä, O | 1 |
| Risteli, L | 1 |
| Stenbäck, F | 1 |
| Lahtela, JT | 1 |
| Risteli, J | 1 |
| Vesell, ES | 1 |
| Murray, RM | 1 |
| Gundert-Remy, U | 1 |
| Marquardt, R | 1 |
| Andritsch, F | 1 |
| Weber, E | 1 |
1 review available for antipyrine and Alcohol Abuse
| Article | Year |
|---|---|
The expanding role of microsomal enzyme induction, and its implications for clinical chemistry.
Topics: Acetaminophen; Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Electron Transport; E | 1980 |
15 other studies available for antipyrine and Alcohol Abuse
| Article | Year |
|---|---|
Hepatic microsomal drug metabolism, glutamyl transferase activity and in vivo antipyrine half-life in rats chronically fed an ethanol diet, a control diet and a chow diet.
Topics: Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Diet; gamma-Glutamyltransferase; Hal | 1980 |
Influence of ethanol on the interaction between polychlorinated biphenyls and drug metabolism.
Topics: Alcoholism; Animals; Antipyrine; Drug Interactions; Ethanol; Humans; Kinetics; Male; Microsomes, Liv | 1980 |
Association between plasma high density lipoprotein cholesterol and antipyrine metabolism in alcoholics.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Antipyrine; Cholesterol; Cholesterol, HDL; Ethanol; Femal | 1982 |
[Oxidative hepatic metabolism in chronic alcoholics during the acute abstinence period: evaluation with antipyrine elimination].
Topics: Adult; Alcoholism; Antipyrine; Female; Humans; Liver; Male; Oxidation-Reduction; Saliva; Temperance | 1993 |
Effect of alcohol abuse and glutathione administration on the circulating levels of glutathione and on antipyrine metabolism in patients with alcoholic liver cirrhosis.
Topics: Adult; Aged; Alcoholism; Antipyrine; Female; Glutathione; Humans; Injections, Intravenous; Liver Cir | 1996 |
Liver size and indices of drug metabolism in alcoholics.
Topics: Adult; Aged; Alcoholism; Antipyrine; Cytochrome P-450 Enzyme System; Female; Humans; Liver; Male; Mi | 1978 |
Impairment of hepatic drug metabolism in alcoholics.
Topics: Adult; Aged; Alcoholism; Antipyrine; Half-Life; Humans; Kinetics; Liver; Liver Function Tests; Male; | 1979 |
Histological changes in the liver and indices of drug metabolism in alcoholics.
Topics: Adult; Aged; Alcoholism; Antipyrine; Cytochrome P-450 Enzyme System; Female; Half-Life; Humans; Kine | 1977 |
Serum zinc and serum copper and indices of drug metabolism in alcoholics.
Topics: Adult; Aged; Alcoholism; Antipyrine; Copper; Cytochrome P-450 Enzyme System; Female; Humans; Liver; | 1977 |
Computed tomography of the brain, hepatotoxic drugs and high alcohol consumption in male alcoholic patients and a random sample from the general male population.
Topics: Adult; Aged; Alcoholism; Analgesics; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Antipyrine; Aspiri | 1992 |
Quinidine disposition in relation to antipyrine elimination and debrisoquine phenotype in alcoholic patients with and without cirrhosis.
Topics: Adult; Aged; Alcoholism; Antipyrine; Chromatography, Liquid; Debrisoquin; Female; Half-Life; Humans; | 1989 |
Fibrotic process and drug metabolism in alcoholic liver disease.
Topics: Adult; Aged; Alcoholism; Antigens; Antipyrine; Basement Membrane; Collagen; Cytochrome P-450 Enzyme | 1986 |
Ethanol metabolism: regulation by genetic factors in normal volunteers under a controlled environment and the effect of chronic ethanol administration.
Topics: Adult; Alcohol Drinking; Alcoholism; Antipyrine; Environment; Ethanol; Female; Genetics, Medical; Ge | 1972 |
The origins of analgesic nephropathy.
Topics: Adult; Affective Symptoms; Aged; Alcoholism; Analgesics; Antipyrine; Aspirin; Codeine; Creatinine; F | 1973 |
[Induction of drug-catabolizing enzymes in chronic alcoholics].
Topics: Alcoholism; Antipyrine; Chronic Disease; Enzyme Induction; Humans; Microsomes, Liver; Pharmaceutical | 1974 |