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antipyrine and Agranulocytosis

antipyrine has been researched along with Agranulocytosis in 10 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
"The risks of agranulocytosis and aplastic anemia in relation to analgesic drug use were evaluated in a population-based case-control study conducted in Europe and Israel."1.27Risks of agranulocytosis and aplastic anemia. A first report of their relation to drug use with special reference to analgesics. The International Agranulocytosis and Aplastic Anemia Study. ( , 1986)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's2 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KIELY, JM1
STICKNEY, JM1
MOESCHLIN, S1
MORENO, R1
ICHIMARU, M1
CHIBU, K1
Delannoy, A1
Schmit, JC1
Cazzola, M1
Chériè Lignière, EL1
Perugini, S1
Tabarelli-Poplawski, S1
Uehleke, H1
Ghizzi, A1
de Caro, L1
Bensi, L1
Berti, P1
Salama, A1
Schütz, B1
Kiefel, V1
Breithaupt, H1
Mueller-Eckhardt, C1
Beritić, T1

Reviews

1 review available for antipyrine and Agranulocytosis

ArticleYear
[Pyrazolone agranulocytoses in the world and in Yugoslavia].
    Lijecnicki vjesnik, 1969, Volume: 91, Issue:4

    Topics: Agranulocytosis; Aminopyrine; Antipyrine; Humans; Pyrazoles; Yugoslavia

1969

Other Studies

9 other studies available for antipyrine and Agranulocytosis

ArticleYear
Agranulocytosis caused by phenylbutazone and 4-amino-antipyrine.
    Proceedings of the staff meetings. Mayo Clinic, 1953, Jun-17, Volume: 28, Issue:12

    Topics: Agranulocytosis; Analgesics; Antipyrine; Phenylbutazone

1953
[Pyramidone agranulocytosis with agglutinins hemophil and heterophil leukocytes].
    Klinische Wochenschrift, 1954, Sep-01, Volume: 32, Issue:33-34

    Topics: Agglutinins; Agranulocytosis; Aminopyrine; Antipyrine; Factor VIII; Hemagglutination; Hemagglutinati

1954
[CASE OF AGRANULOCYTOSIS SHOWING A LEUKEMOID REACTION DURING THE RECOVERY PHASE].
    Naika. Internal medicine, 1964, Volume: 14

    Topics: Adrenal Cortex Hormones; Agranulocytosis; Antipyrine; Blood; Bone Marrow Examination; Chloramphenico

1964
A granulocytosis after cutaneous contact with phenazone.
    European journal of haematology, 1993, Volume: 50, Issue:2

    Topics: Administration, Topical; Adult; Agranulocytosis; Antipyrine; Female; Humans; Skin

1993
[Chronic granulocytopenia associated with exposure to isopropylphenazone, complicated by two episodes of acute agranulocytosis caused by aminopyrine (author's transl)].
    Haematologica, 1978, Volume: 63, Issue:1

    Topics: Agranulocytosis; Aminopyrine; Antipyrine; Female; Humans; Menopause, Premature; Middle Aged; Neutrop

1978
Irreversible binding of 3-14C-antipyrine to hepatic protein in vivo and in metabolizing liver microsomes.
    Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 297, Issue:1

    Topics: Agranulocytosis; Animals; Antipyrine; Drug Hypersensitivity; Hydroxylation; Liver; Male; Mice; Micro

1977
[In vitro activity of folic acid on the proliferation dynamics of human bone marrow CFU-GM in propyphenazone-induced granulocytopenia].
    Bollettino della Societa italiana di biologia sperimentale, 1991, Volume: 67, Issue:6

    Topics: Agranulocytosis; Antipyrine; Cell Division; Cells, Cultured; Feedback; Female; Folic Acid; Granulocy

1991
Immune-mediated agranulocytosis related to drugs and their metabolites: mode of sensitization and heterogeneity of antibodies.
    British journal of haematology, 1989, Volume: 72, Issue:2

    Topics: Adolescent; Adult; Agranulocytosis; Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Antibodies

1989
Risks of agranulocytosis and aplastic anemia. A first report of their relation to drug use with special reference to analgesics. The International Agranulocytosis and Aplastic Anemia Study.
    JAMA, 1986, Oct-03, Volume: 256, Issue:13

    Topics: Acetaminophen; Adult; Aged; Agranulocytosis; Aminopyrine; Analgesics; Anemia, Aplastic; Antipyrine;

1986