antipyrine has been researched along with Acute-Phase Reaction in 4 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Acute-Phase Reaction: An early local inflammatory reaction to insult or injury that consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Twenty-four hours after LPS injection, the pharmacokinetic parameters of the four drugs were obtained following intravenous administrations of antipyrine (7 mg/kg), theophylline (5 mg/kg), phenytoin (10 mg/kg) and nifedipine (1 mg/kg)." | 1.31 | The impact of acute phase response on the plasma clearance of antipyrine, theophylline, phenytoin and nifedipine in rabbits. ( Kokue, E; Saitoh, T; Shimoda, M, 2000) |
| "Antipyrine was administered (5 mg/kg) at 24 h (control and group I), 3 days (group II) and 7 days (group III) after the first LPS injection." | 1.30 | The suppressive effects of lipopolysaccharide-induced acute phase response on hepatic cytochrome P450-dependent drug metabolism in rabbits. ( Kokue, E; Saitoh, T; Shimoda, M, 1999) |
| " The estimated pharmacokinetic values of antipyrine (AP) in EP-infected goats were similar to those in the goats when healthy." | 1.28 | Effects of Ehrlichia phagocytophila infection on serum thyroid hormone concentrations and on antipyrine clearance and metabolite formation in dwarf goats. ( Nijmeijer, SM; Offiah, VN; van Duin, CT; van Miert, AS; Witkamp, RF, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katayama, Y | 1 |
| Igarashi, H | 1 |
| Saitoh, T | 2 |
| Kokue, E | 2 |
| Shimoda, M | 2 |
| Offiah, VN | 1 |
| Nijmeijer, SM | 1 |
| van Duin, CT | 1 |
| Witkamp, RF | 1 |
| van Miert, AS | 1 |
1 review available for antipyrine and Acute-Phase Reaction
| Article | Year |
|---|---|
[Advances in the diagnosis and treatment of cerebral ischemia during the acute phase].
Topics: Acute-Phase Reaction; Antipyrine; Brain Ischemia; Cerebrovascular Circulation; Drug Design; Drug The | 2003 |
3 other studies available for antipyrine and Acute-Phase Reaction
| Article | Year |
|---|---|
The suppressive effects of lipopolysaccharide-induced acute phase response on hepatic cytochrome P450-dependent drug metabolism in rabbits.
Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Blotting, Wester | 1999 |
The impact of acute phase response on the plasma clearance of antipyrine, theophylline, phenytoin and nifedipine in rabbits.
Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antipyrine; | 2000 |
Effects of Ehrlichia phagocytophila infection on serum thyroid hormone concentrations and on antipyrine clearance and metabolite formation in dwarf goats.
Topics: Acute-Phase Reaction; Animals; Antipyrine; Ehrlichiosis; Goat Diseases; Goats; Male; Thyroxine; Trii | 1992 |