antipyrine has been researched along with Acute Disease in 56 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of edaravone, a free radical scavenger, on long-term prognosis and its efficacy with regards to scavenging injurious free radicals in patients with acute myocardial infarction (AMI) was examined." | 9.12 | Long-term efficacy of edaravone in patients with acute myocardial infarction. ( Fukuda, M; Hokamaki, J; Kaikita, K; Kawano, H; Nagayoshi, Y; Nakamura, Y; Ogawa, H; Sakamoto, T; Shimomura, H; Tsujita, K; Yamashita, T; Yoshimura, M, 2006) |
| "The efficacy of hyperbaric oxygen (HBO) therapy combined with intravenous edaravone (free radical scavenger) administration was prospectively investigated in patients with acute embolic stroke involving the anterior cerebral circulation." | 9.12 | Hyperbaric oxygen combined with intravenous edaravone for treatment of acute embolic stroke: a pilot clinical trial. ( Imai, K; Izumoto, H; Kunieda, T; Mori, T; Takabatake, N; Watanabe, M, 2006) |
| "To investigate the effect of a free-radical scavenger, edaravone, on the changes occurring with acute urinary retention (AUR) and subsequent catheterization in the rat bladder." | 7.75 | Acute urinary retention and subsequent catheterization cause lipid peroxidation and oxidative DNA damage in the bladder: preventive effect of edaravone, a free-radical scavenger. ( Kazuyama, E; Kinoshita, Y; Saito, M; Satoh, I; Satoh, K; Shimizu, S; Tamamura, M, 2009) |
| " In the first, the dose-dependent effects of edaravone on ICH-induced brain injury were examined by measuring brain edema and neurologic deficits." | 7.74 | Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage. ( Itano, T; Keep, RF; Kuroda, Y; Miyamoto, O; Nagao, S; Nakamura, T; Tamiya, T; Xi, G; Yamashita, S; Zhang, X, 2008) |
| "In this study, we tested the hypothesis that MCI-186 (3-methyl-1-phenyl-2-pyrazolin-5-one; edaravone), a novel free radical scavenger, protects against acute experimental autoimmune myocarditis (EAM) in rats by the radical scavenging action associated with the suppression of cytotoxic myocardial injury." | 7.73 | MCI-186 (edaravone), a novel free radical scavenger, protects against acute autoimmune myocarditis in rats. ( Hattori, M; Kishimoto, C; Nimata, M; Okabe, TA; Shioji, K; Yuan, Z, 2005) |
| " With use of this system we studied whether human serum obtained from patients with acute cerebral infarction (n = 16) would have a proliferative effect on vessels and whether an administration of a free radical scavenger, edaravone, with or without amlodipine would elicit antiproliferative effects." | 7.72 | [Alterations of antiproliferative effects of serum obtained from patients with acute cerebral infarction treated with a radical scavenger, edaravone, with or without amlodipine using an in vitro cultured basilar artery smooth muscle cells]. ( Echizen, H; Hiraga, M; Ida, T; Kobayashi, T; Oishi, K; Uchida, MK; Yamaguchi, T, 2004) |
| "Experiments in rats with different sensitivity to hypobaric hypoxia established bimodal distribution of antipyrine and isoniazide half-lives." | 7.68 | [The effect of acute hypoxia on antipyrine and isoniazid pharmacokinetics in rats with different resistances to oxygen deficiency]. ( Grek, OR; Kolpakov, MA; Sharapov, VI, 1993) |
| "When edaravone was administered prior to ischemia and at the time of initiation of the reperfusion, liver injury was markedly reduced." | 5.33 | Electron spin resonance and spin trapping technique provide direct evidence that edaravone prevents acute ischemia-reperfusion injury of the liver by limiting free radical-mediated tissue damage. ( Connor, HD; Fujii, H; Kono, H; Maki, A; Mason, RP; Rusyn, I; Woods, CG, 2006) |
| "The effect of edaravone, a free radical scavenger, on long-term prognosis and its efficacy with regards to scavenging injurious free radicals in patients with acute myocardial infarction (AMI) was examined." | 5.12 | Long-term efficacy of edaravone in patients with acute myocardial infarction. ( Fukuda, M; Hokamaki, J; Kaikita, K; Kawano, H; Nagayoshi, Y; Nakamura, Y; Ogawa, H; Sakamoto, T; Shimomura, H; Tsujita, K; Yamashita, T; Yoshimura, M, 2006) |
| "The efficacy of hyperbaric oxygen (HBO) therapy combined with intravenous edaravone (free radical scavenger) administration was prospectively investigated in patients with acute embolic stroke involving the anterior cerebral circulation." | 5.12 | Hyperbaric oxygen combined with intravenous edaravone for treatment of acute embolic stroke: a pilot clinical trial. ( Imai, K; Izumoto, H; Kunieda, T; Mori, T; Takabatake, N; Watanabe, M, 2006) |
| "To determine the efficacy of Auralgan otic solution (combination product of antipyrine, benzocaine, and glycerin) compared with an olive oil placebo in the management of moderate to severe ear pain in children with acute otitis media (AOM)." | 5.08 | Efficacy of Auralgan for treating ear pain in children with acute otitis media. ( Hoberman, A; Paradise, JL; Reynolds, EA; Urkin, J, 1997) |
| "To investigate the effect of a free-radical scavenger, edaravone, on the changes occurring with acute urinary retention (AUR) and subsequent catheterization in the rat bladder." | 3.75 | Acute urinary retention and subsequent catheterization cause lipid peroxidation and oxidative DNA damage in the bladder: preventive effect of edaravone, a free-radical scavenger. ( Kazuyama, E; Kinoshita, Y; Saito, M; Satoh, I; Satoh, K; Shimizu, S; Tamamura, M, 2009) |
| " In the first, the dose-dependent effects of edaravone on ICH-induced brain injury were examined by measuring brain edema and neurologic deficits." | 3.74 | Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage. ( Itano, T; Keep, RF; Kuroda, Y; Miyamoto, O; Nagao, S; Nakamura, T; Tamiya, T; Xi, G; Yamashita, S; Zhang, X, 2008) |
| "In this study, we tested the hypothesis that MCI-186 (3-methyl-1-phenyl-2-pyrazolin-5-one; edaravone), a novel free radical scavenger, protects against acute experimental autoimmune myocarditis (EAM) in rats by the radical scavenging action associated with the suppression of cytotoxic myocardial injury." | 3.73 | MCI-186 (edaravone), a novel free radical scavenger, protects against acute autoimmune myocarditis in rats. ( Hattori, M; Kishimoto, C; Nimata, M; Okabe, TA; Shioji, K; Yuan, Z, 2005) |
| "Fatty degeneration and necrosis with marked elevation of serum alanine aminotransferase and lactate dehydrogenase levels developed after CCl4 administration were significantly reduced by edaravone." | 3.72 | A free radical scavenger, edaravone, attenuates steatosis and cell death via reducing inflammatory cytokine production in rat acute liver injury. ( Ishii, H; Kameyama, K; Kitamura, K; Kurita, S; Nakamoto, N; Saito, H; Saito, Y; Tada, S, 2003) |
| " With use of this system we studied whether human serum obtained from patients with acute cerebral infarction (n = 16) would have a proliferative effect on vessels and whether an administration of a free radical scavenger, edaravone, with or without amlodipine would elicit antiproliferative effects." | 3.72 | [Alterations of antiproliferative effects of serum obtained from patients with acute cerebral infarction treated with a radical scavenger, edaravone, with or without amlodipine using an in vitro cultured basilar artery smooth muscle cells]. ( Echizen, H; Hiraga, M; Ida, T; Kobayashi, T; Oishi, K; Uchida, MK; Yamaguchi, T, 2004) |
| "Experiments in rats with different sensitivity to hypobaric hypoxia established bimodal distribution of antipyrine and isoniazide half-lives." | 3.68 | [The effect of acute hypoxia on antipyrine and isoniazid pharmacokinetics in rats with different resistances to oxygen deficiency]. ( Grek, OR; Kolpakov, MA; Sharapov, VI, 1993) |
| "In 33 patients with acute hepatic encephalopathy due to toxic or viral hepatitis the following analyses were performed: (24-14C)cholic acid conjugation and sulfation, plasma phenazone clearance, galactose elimination capacity, and concentrations of glycocholic acid and glycolithocholic acid sulfate in plasma." | 3.66 | Cholic acid conjugation test and quantitative liver function in acute liver failure. ( Andreasen, PB; Bahnsen, M; Bremmelgaard, A; Christensen, E; Ranek, L, 1983) |
| "Patients with acute hepatitis and patients with compensated or decompensated cirrhosis of the liver have a decreased plasma clearance of hexobarbital." | 3.66 | [Drug metabolism in patients with liver disease (author's transl)]. ( Epping, J; Fuchshofen-Röckel, M; Heusler, H; Richter, E; Zilly, W, 1980) |
| "The urinary excretion of D-glucaric acid and the plasma clearance of antipyrine were estimated during the acute phase of viral hepatitis and again during recovery." | 3.65 | Paradoxical urinary excretion of D-glucaric acid in acute viral hepatitis. ( Barak, AJ; Burnett, DA; Sorrell, MF; Tuma, DJ, 1976) |
| "Results of the use of ampicillin, penicillin G and symptomatic therapy in the treatment of acute otitis media in 142 children were compared." | 3.65 | Treatment of acute otitis media: a controlled study of 142 children. ( Jones, RH; Laxdal, OE; Merida, J, 1970) |
| "Edaravone was infused at a dose of 30 mg, twice a day, for 14 days." | 2.71 | Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters. ( , 2003) |
| " The results show that phenazone at a dosage of 1000 mg is effective and well tolerated in the treatment of acute migraine attacks." | 2.71 | Efficacy of phenazone in the treatment of acute migraine attacks: a double-blind, placebo-controlled, randomized study. ( Göbel, H; Heinze, A; Niederberger, U; Witt, T; Zumbroich, V, 2004) |
| "Acute brain damage and delayed encephalopathy are the most serious complication, yet their pathogenesis is poorly understood." | 1.43 | Edaravone attenuates brain damage in rats after acute CO poisoning through inhibiting apoptosis and oxidative stress. ( Bi, MJ; Bi, WK; Guo, YL; Kang, H; Li, Q; Yan, le J, 2016) |
| "He had been treated for lung cancer by chemotherapy and irradiation 3 years earlier." | 1.40 | [Case of cardiac tamponade during the treatment of acute cerebral infarction]. ( Nagasawa, H; Ono, H; Tanaka, H; Yamakawa, T, 2014) |
| "Edaravone was administered intravenously as a bolus dose of 5 mg/kg at 5 minutes, 24 hours, and 48 hours after injury (edaravone-treated rats)." | 1.33 | Neuroprotection and enhanced recovery with edaravone after acute spinal cord injury in rats. ( Iwashita, Y; Kuno, S; Nakamura, T; Ohta, S; Takada, H, 2005) |
| "When edaravone was administered prior to ischemia and at the time of initiation of the reperfusion, liver injury was markedly reduced." | 1.33 | Electron spin resonance and spin trapping technique provide direct evidence that edaravone prevents acute ischemia-reperfusion injury of the liver by limiting free radical-mediated tissue damage. ( Connor, HD; Fujii, H; Kono, H; Maki, A; Mason, RP; Rusyn, I; Woods, CG, 2006) |
| "In 22 patients with acute pancreatitis caused by biliary calculi and 9 healthy controls the rate of hepatic elimination of phenazone was measured." | 1.28 | [Effect of acute biliary pancreatitis on liver metabolism of phenazone]. ( Becker, A; Hartleb, M; Kacperek, T; Mańczyk, I; Nowak, A; Nowakowska-Duława, E, 1990) |
| "Antipyrine is a pyrazole derivative used extensively as a marker for hepatic drug metabolizing enzyme activity." | 1.28 | Allergic reaction to antipyrine, a marker of hepatic enzyme activity. ( McCrea, JB; Rocci, ML; Vlasses, PH, 1989) |
| "[14C]iodoantipyrine was used as a tracer." | 1.27 | Regional cerebral blood flow in acute experimental allergic encephalomyelitis. ( Juhler, M; Paulson, OB, 1986) |
| "Antipyrine metabolism was normal or marginally impaired in patients with compensated cirrhosis or acute hepatitis, whereas it was frequently abnormal in those with chronic active hepatitis or advanced alcoholic liver disease." | 1.26 | Drug metabolism in liver disease. Identification of patients with impaired hepatic drug metabolism. ( Cooksley, WG; Farrell, GC; Hart, P; Powell, LW, 1978) |
| " Estimates of clearance, volume of distribution, and half-life made from either plasma or saliva samples were not statistically different in these subjects." | 1.26 | Application of salivary concentration data to pharmacokinetic studies with antipyrine. ( Blaschke, TF; Meffin, PJ; Rowland, M; Williams, RL, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (37.50) | 18.7374 |
| 1990's | 12 (21.43) | 18.2507 |
| 2000's | 17 (30.36) | 29.6817 |
| 2010's | 6 (10.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takahashi, S | 1 |
| Nagasawa, H | 1 |
| Ono, H | 1 |
| Tanaka, H | 1 |
| Yamakawa, T | 1 |
| Li, Q | 1 |
| Bi, MJ | 1 |
| Bi, WK | 1 |
| Kang, H | 1 |
| Yan, le J | 1 |
| Guo, YL | 1 |
| Higashi, Y | 1 |
| Shimizu, S | 1 |
| Saito, M | 1 |
| Kinoshita, Y | 1 |
| Kazuyama, E | 1 |
| Tamamura, M | 1 |
| Satoh, I | 1 |
| Satoh, K | 1 |
| Yamakawa, H | 1 |
| Yoshimura, S | 1 |
| Iwama, T | 1 |
| Isahaya, K | 1 |
| Yamada, K | 1 |
| Yamatoku, M | 1 |
| Sakurai, K | 1 |
| Takaishi, S | 1 |
| Kato, B | 1 |
| Hirayama, T | 1 |
| Hasegawa, Y | 1 |
| Xin, Y | 1 |
| Zhang, S | 1 |
| Gu, L | 1 |
| Liu, S | 1 |
| Gao, H | 1 |
| You, Z | 1 |
| Zhou, G | 1 |
| Wen, L | 1 |
| Yu, J | 1 |
| Xuan, Y | 1 |
| Wadiwala, MF | 1 |
| Sonawalla, A | 1 |
| Kamal, AK | 1 |
| Satoh, M | 1 |
| Kashihara, N | 1 |
| Fujimoto, S | 1 |
| Horike, H | 1 |
| Tokura, T | 1 |
| Namikoshi, T | 1 |
| Sasaki, T | 1 |
| Makino, H | 1 |
| Nakamoto, N | 1 |
| Tada, S | 1 |
| Kameyama, K | 1 |
| Kitamura, K | 1 |
| Kurita, S | 1 |
| Saito, Y | 1 |
| Saito, H | 1 |
| Ishii, H | 1 |
| Yamaguchi, T | 1 |
| Ida, T | 1 |
| Kobayashi, T | 1 |
| Hiraga, M | 1 |
| Oishi, K | 1 |
| Uchida, MK | 1 |
| Echizen, H | 1 |
| Göbel, H | 1 |
| Heinze, A | 1 |
| Niederberger, U | 1 |
| Witt, T | 1 |
| Zumbroich, V | 1 |
| Ohta, S | 1 |
| Iwashita, Y | 1 |
| Takada, H | 1 |
| Kuno, S | 1 |
| Nakamura, T | 2 |
| Mishina, M | 1 |
| Komaba, Y | 1 |
| Kobayashi, S | 1 |
| Tanaka, N | 1 |
| Kominami, S | 1 |
| Fukuchi, T | 1 |
| Mizunari, T | 1 |
| Hamamoto, M | 1 |
| Teramoto, A | 1 |
| Katayama, Y | 1 |
| Nimata, M | 1 |
| Okabe, TA | 1 |
| Hattori, M | 1 |
| Yuan, Z | 1 |
| Shioji, K | 1 |
| Kishimoto, C | 1 |
| Kono, H | 1 |
| Woods, CG | 1 |
| Maki, A | 1 |
| Connor, HD | 1 |
| Mason, RP | 1 |
| Rusyn, I | 1 |
| Fujii, H | 1 |
| Tsujita, K | 1 |
| Shimomura, H | 1 |
| Kaikita, K | 1 |
| Kawano, H | 1 |
| Hokamaki, J | 1 |
| Nagayoshi, Y | 1 |
| Yamashita, T | 1 |
| Fukuda, M | 1 |
| Nakamura, Y | 1 |
| Sakamoto, T | 1 |
| Yoshimura, M | 1 |
| Ogawa, H | 1 |
| Ferrington, L | 1 |
| Kirilly, E | 1 |
| McBean, DE | 1 |
| Olverman, HJ | 1 |
| Bagdy, G | 1 |
| Kelly, PA | 1 |
| Imai, K | 1 |
| Mori, T | 1 |
| Izumoto, H | 1 |
| Takabatake, N | 1 |
| Kunieda, T | 1 |
| Watanabe, M | 1 |
| Murakami, T | 1 |
| Nakayasu, H | 1 |
| Doi, M | 1 |
| Fukada, Y | 1 |
| Hayashi, M | 1 |
| Suzuki, T | 1 |
| Takeuchi, Y | 1 |
| Nakashima, K | 1 |
| Kuroda, Y | 1 |
| Yamashita, S | 1 |
| Zhang, X | 1 |
| Miyamoto, O | 1 |
| Tamiya, T | 1 |
| Nagao, S | 1 |
| Xi, G | 1 |
| Keep, RF | 1 |
| Itano, T | 1 |
| Okonek, S | 1 |
| Reinecke, HJ | 1 |
| Bremmelgaard, A | 1 |
| Ranek, L | 2 |
| Bahnsen, M | 1 |
| Andreasen, PB | 2 |
| Christensen, E | 1 |
| Ramsøe, K | 1 |
| Buchanan, N | 1 |
| Davis, M | 1 |
| Danhof, M | 1 |
| Breimer, DD | 1 |
| Richter, E | 1 |
| Epping, J | 1 |
| Fuchshofen-Röckel, M | 1 |
| Heusler, H | 1 |
| Zilly, W | 1 |
| Imamura, H | 1 |
| Sharapov, VI | 2 |
| Kolpakov, MA | 1 |
| Grek, OR | 1 |
| Takagi, K | 1 |
| Zhao, W | 1 |
| Busto, R | 1 |
| Ginsberg, MD | 1 |
| Hoberman, A | 1 |
| Paradise, JL | 1 |
| Reynolds, EA | 1 |
| Urkin, J | 1 |
| Woldman, S | 1 |
| Tuter, NV | 1 |
| Danilov, AB | 1 |
| Poliakova, LV | 1 |
| Wei, L | 1 |
| Craven, K | 1 |
| Erinjeri, J | 1 |
| Liang, GE | 1 |
| Bereczki, D | 1 |
| Rovainen, CM | 1 |
| Woolsey, TA | 1 |
| Fenstermacher, JD | 1 |
| Gichev, IuP | 1 |
| Guseva, EO | 1 |
| Grek, OP | 1 |
| Mach, T | 1 |
| Barylak, H | 1 |
| Farrell, GC | 1 |
| Cooksley, WG | 1 |
| Hart, P | 1 |
| Powell, LW | 1 |
| Prescott, LF | 1 |
| Forrest, JA | 1 |
| Adjepon-Yamoah, KK | 1 |
| Finlayson, ND | 1 |
| Meffin, PJ | 1 |
| Williams, RL | 1 |
| Blaschke, TF | 1 |
| Rowland, M | 1 |
| Sorrell, MF | 1 |
| Burnett, DA | 1 |
| Tuma, DJ | 1 |
| Barak, AJ | 1 |
| Razzakov, SM | 1 |
| Krakovskiĭ, ME | 1 |
| Ashirmetov, AKh | 1 |
| Murphy, VA | 1 |
| Johanson, CE | 1 |
| Kagaya, Y | 1 |
| Kanno, Y | 1 |
| Takeyama, D | 1 |
| Ishide, N | 1 |
| Maruyama, Y | 1 |
| Takahashi, T | 1 |
| Ido, T | 1 |
| Takishima, T | 1 |
| Hartleb, M | 1 |
| Nowak, A | 1 |
| Nowakowska-Duława, E | 1 |
| Mańczyk, I | 1 |
| Becker, A | 1 |
| Kacperek, T | 1 |
| McCrea, JB | 1 |
| Vlasses, PH | 1 |
| Rocci, ML | 1 |
| Herrick, A | 1 |
| McColl, KE | 1 |
| McLellan, A | 1 |
| Moore, MR | 1 |
| Brodie, MJ | 1 |
| Goldberg, A | 1 |
| Lares-Asseff, I | 1 |
| Santiago-Porras, MP | 1 |
| Pérez-Ortiz, B | 1 |
| Cravioto, J | 1 |
| Juhler, M | 1 |
| Paulson, OB | 1 |
| Okeda, R | 1 |
| Matsuo, T | 1 |
| Kuroiwa, T | 1 |
| Nakai, M | 1 |
| Tajima, T | 1 |
| Takahashi, H | 1 |
| Lukaszyk, A | 1 |
| Laxdal, OE | 1 |
| Merida, J | 1 |
| Jones, RH | 1 |
| Gerlach, E | 1 |
| Bogusz, M | 1 |
| Blair, RD | 1 |
| Waltz, AG | 1 |
| Fieschi, C | 1 |
4 reviews available for antipyrine and Acute Disease
| Article | Year |
|---|---|
Edaravone for the treatment of acute cerebral infarction: role of endothelium-derived nitric oxide and oxidative stress.
Topics: Acute Disease; Antipyrine; Cerebral Infarction; Edaravone; Endothelium, Vascular; Free Radical Scave | 2009 |
Acute toxicity of pyrazolones.
Topics: Acute Disease; Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Dipyrone; Diuresis; | 1983 |
[Antipyrine elimination in acute toxic hepatitis in rats].
Topics: Acute Disease; Animals; Antipyrine; Biotransformation; Carbon Tetrachloride Poisoning; Chemical and | 1978 |
Drug metabolism in liver disease.
Topics: Acetaminophen; Acute Disease; Antipyrine; Chemical and Drug Induced Liver Injury; Chronic Disease; H | 1975 |
5 trials available for antipyrine and Acute Disease
| Article | Year |
|---|---|
Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antipyrine; Cerebral Infarction; Double-Blind Method; | 2003 |
Efficacy of phenazone in the treatment of acute migraine attacks: a double-blind, placebo-controlled, randomized study.
Topics: Acute Disease; Adult; Aged; Antipyrine; Chi-Square Distribution; Double-Blind Method; Female; Humans | 2004 |
Long-term efficacy of edaravone in patients with acute myocardial infarction.
Topics: Acute Disease; Antipyrine; Arrhythmias, Cardiac; Edaravone; Free Radical Scavengers; Humans; Myocard | 2006 |
Hyperbaric oxygen combined with intravenous edaravone for treatment of acute embolic stroke: a pilot clinical trial.
Topics: Acute Disease; Aged; Antipyrine; Combined Modality Therapy; Edaravone; Emergency Medical Services; F | 2006 |
Efficacy of Auralgan for treating ear pain in children with acute otitis media.
Topics: Acute Disease; Adolescent; Adult; Antipyrine; Benzocaine; Child; Child, Preschool; Double-Blind Meth | 1997 |
47 other studies available for antipyrine and Acute Disease
| Article | Year |
|---|---|
[Treatment of acute ischemic stroke: tissue clock and reperfusion].
Topics: Acute Disease; Adult; Animals; Antipyrine; Brain Infarction; Edaravone; Free Radical Scavengers; Hum | 2012 |
[Case of cardiac tamponade during the treatment of acute cerebral infarction].
Topics: Acute Disease; Adenocarcinoma; Anterior Cerebral Artery; Antipyrine; Aspirin; Cardiac Tamponade; Cer | 2014 |
Edaravone attenuates brain damage in rats after acute CO poisoning through inhibiting apoptosis and oxidative stress.
Topics: Acute Disease; Animals; Antipyrine; Apoptosis; Brain; Brain Diseases; Carbon Monoxide Poisoning; Eda | 2016 |
Acute urinary retention and subsequent catheterization cause lipid peroxidation and oxidative DNA damage in the bladder: preventive effect of edaravone, a free-radical scavenger.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Animals; Antipyrine; Deoxyguanosine; DNA Damage; Edaravo | 2009 |
Anterior spinal artery as a collateral channel in patients with acute bilateral vertebral artery occlusions. Two case reports.
Topics: Acute Disease; Aged; Antipyrine; Arginine; Brain Stem; Cerebellum; Cerebral Revascularization; Cereb | 2009 |
Effects of edaravone, a free radical scavenger, on serum levels of inflammatory biomarkers in acute brain infarction.
Topics: Acute Disease; Aged; Aged, 80 and over; Analysis of Variance; Antipyrine; Biomarkers; Brain Infarcti | 2012 |
Electrocardiographic and biochemical evidence for the cardioprotective effect of antioxidants in acute doxorubicin-induced cardiotoxicity in the beagle dogs.
Topics: Acute Disease; Alanine Transaminase; Animals; Antibiotics, Antineoplastic; Antioxidants; Antipyrine; | 2011 |
What is the role of free radical scavengers in acute stroke?
Topics: Acute Disease; Antipyrine; Biomarkers; Brain Infarction; Edaravone; Enzyme-Linked Immunosorbent Assa | 2012 |
A novel free radical scavenger, edarabone, protects against cisplatin-induced acute renal damage in vitro and in vivo.
Topics: Acute Disease; Animals; Antipyrine; Apoptosis; Cell Size; Cell Survival; Cisplatin; Edaravone; Free | 2003 |
A free radical scavenger, edaravone, attenuates steatosis and cell death via reducing inflammatory cytokine production in rat acute liver injury.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Alanine Transaminase; Aldehydes; Animals; Antipyrine; Ap | 2003 |
[Alterations of antiproliferative effects of serum obtained from patients with acute cerebral infarction treated with a radical scavenger, edaravone, with or without amlodipine using an in vitro cultured basilar artery smooth muscle cells].
Topics: Acute Disease; Aged; Amlodipine; Animals; Antioxidants; Antipyrine; Basilar Artery; Calcium Channel | 2004 |
Neuroprotection and enhanced recovery with edaravone after acute spinal cord injury in rats.
Topics: Acute Disease; Animals; Antipyrine; Edaravone; Free Radical Scavengers; Hindlimb; Injections, Intrav | 2005 |
Efficacy of edaravone, a free radical scavenger, for the treatment of acute lacunar infarction.
Topics: Acute Disease; Aged; Antipyrine; Brain Infarction; Edaravone; Female; Free Radical Scavengers; Human | 2005 |
MCI-186 (edaravone), a novel free radical scavenger, protects against acute autoimmune myocarditis in rats.
Topics: Acute Disease; Animals; Antipyrine; Autoimmune Diseases; Cardiotonic Agents; Cytokines; Dose-Respons | 2005 |
Electron spin resonance and spin trapping technique provide direct evidence that edaravone prevents acute ischemia-reperfusion injury of the liver by limiting free radical-mediated tissue damage.
Topics: Acute Disease; Animals; Antipyrine; Edaravone; Electron Spin Resonance Spectroscopy; Free Radicals; | 2006 |
Persistent cerebrovascular effects of MDMA and acute responses to the drug.
Topics: Acute Disease; Animals; Antipyrine; Autonomic Pathways; Carbon Radioisotopes; Cerebral Arteries; Cer | 2006 |
Anterior and posterior inferior cerebellar artery infarction with sudden deafness and vertigo.
Topics: Acute Disease; Antipyrine; Aspirin; Basilar Artery; Brain Infarction; Cerebellar Diseases; Cerebellu | 2006 |
Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage.
Topics: Acute Disease; Animals; Antipyrine; Basal Ganglia; Brain Edema; Cerebral Cortex; Cerebral Hemorrhage | 2008 |
Cholic acid conjugation test and quantitative liver function in acute liver failure.
Topics: Acute Disease; Antipyrine; Chemical and Drug Induced Liver Injury; Cholic Acids; Diagnosis, Differen | 1983 |
Functioning liver mass in uncomplicated and fulminant acute hepatitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Alanine Transaminase; Antipyrine; Bilirubin; Chemical and Dr | 1980 |
Antipyrine metabolite formation in children in the acute phase of malnutrition and after recovery.
Topics: Acute Disease; Antipyrine; Child, Preschool; Glucuronates; Humans; Infant; Kinetics; Kwashiorkor | 1980 |
[Drug metabolism in patients with liver disease (author's transl)].
Topics: Acute Disease; Adult; Antipyrine; Biological Availability; Biotransformation; Cholestasis; Female; H | 1980 |
[Effects of megadose methylprednisolone therapy on acute spinal cord injury in rats].
Topics: Acute Disease; Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Methylprednisolone; Rats; | 1994 |
[The effect of acute hypoxia on antipyrine and isoniazid pharmacokinetics in rats with different resistances to oxygen deficiency].
Topics: Acute Disease; Animals; Antipyrine; Atmosphere Exposure Chambers; Disease Susceptibility; Half-Life; | 1993 |
Local hemodynamic changes during transient middle cerebral artery occlusion and recirculation in the rat: a [14C]iodoantipyrine autoradiographic study.
Topics: Acute Disease; Analysis of Variance; Animals; Antipyrine; Arterial Occlusive Diseases; Autoradiograp | 1995 |
Treating ear pain in children with acute otitis media.
Topics: Acute Disease; Antipyrine; Benzocaine; Child; Drug Combinations; Ear; Earache; Humans; Instillation, | 1998 |
[The treatment of a complex regional pain syndrome].
Topics: Acetaminophen; Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Cerebro | 1997 |
Local cerebral blood flow during the first hour following acute ligation of multiple arterioles in rat whisker barrel cortex.
Topics: Acute Disease; Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Arterial Oc | 1998 |
[Antipyrine pharmacokinetics in rats with various resistance to hypoxia during cold stress].
Topics: Acute Disease; Animals; Antipyrine; Cold Temperature; Hypoxia; Male; Rats; Rats, Wistar; Species Spe | 1998 |
Drug metabolism in liver disease. Identification of patients with impaired hepatic drug metabolism.
Topics: Acute Disease; Antipyrine; Ascites; Biotransformation; Chemical and Drug Induced Liver Injury; Chole | 1978 |
Application of salivary concentration data to pharmacokinetic studies with antipyrine.
Topics: Acute Disease; Antipyrine; Hepatitis, Viral, Human; Humans; Kinetics; Male; Saliva | 1977 |
Paradoxical urinary excretion of D-glucaric acid in acute viral hepatitis.
Topics: Acute Disease; Antipyrine; Female; Glucaric Acid; Hepatitis A; Humans; Male; Phenobarbital; Sugar Ac | 1976 |
[Detoxification function of the liver and body resistance in patients with acute intestinal obstruction].
Topics: Acute Disease; Adult; Aged; Antipyrine; Biotransformation; Humans; Immune Tolerance; Intestinal Obst | 1990 |
Na(+)-H+ exchange in choroid plexus and CSF in acute metabolic acidosis or alkalosis.
Topics: Acid-Base Equilibrium; Acidosis; Acute Disease; Alkalosis; Amiloride; Animals; Antipyrine; Arteries; | 1990 |
Effects of long-term pressure overload on regional myocardial glucose and free fatty acid uptake in rats. A quantitative autoradiographic study.
Topics: Acute Disease; Animals; Antipyrine; Autoradiography; Blood Glucose; Chronic Disease; Fatty Acids; Fa | 1990 |
[Effect of acute biliary pancreatitis on liver metabolism of phenazone].
Topics: Acute Disease; Adult; Aged; Antipyrine; Biotransformation; Cholelithiasis; Female; Humans; Liver; Li | 1990 |
Allergic reaction to antipyrine, a marker of hepatic enzyme activity.
Topics: Acute Disease; Adult; Antipyrine; Drug Hypersensitivity; Humans; Liver; Male | 1989 |
Effect of haem arginate therapy on porphyrin metabolism and mixed function oxygenase activity in acute hepatic porphyria.
Topics: Acute Disease; Adult; Antipyrine; Arginine; Cytochrome P-450 Enzyme System; Depression, Chemical; Fe | 1987 |
[Pharmacokinetics of antipyrine in grade III malnourished children during the acute phase and recovery].
Topics: Acute Disease; Antipyrine; Child; Child, Preschool; Convalescence; Female; Half-Life; Humans; Infant | 1988 |
Regional cerebral blood flow in acute experimental allergic encephalomyelitis.
Topics: Acute Disease; Animals; Antipyrine; Autoradiography; Blood-Brain Barrier; Brain; Cerebral Cortex; En | 1986 |
Regional cerebral blood flow of acute carbon monoxide poisoning in cats.
Topics: Acute Disease; Animals; Antipyrine; Blood Pressure; Brain; Carbon Monoxide Poisoning; Carbon Radiois | 1987 |
[Hepatic metabolism of antipyrine in patients with acute pancreatitis].
Topics: Acute Disease; Adult; Aged; Antipyrine; Female; Humans; Inactivation, Metabolic; Kinetics; Liver; Ma | 1987 |
Treatment of acute otitis media: a controlled study of 142 children.
Topics: Acute Disease; Adolescent; Ampicillin; Antipyrine; Aspirin; Benzocaine; Child; Child, Preschool; Hum | 1970 |
[Significance of ichthyol in gynecology].
Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Antipyrine; Atropa belladonna; Barbiturates | 1969 |
[The effect of chronic drug abuse on the course of acute poisoning (author's transl)].
Topics: Acute Disease; Antipyrine; Enzyme Induction; Enzymes; Half-Life; Humans; Hypnotics and Sedatives; Po | 1974 |
Regional cerebral blood flow during acute ischemia. Correlation of autoradiographic measurements with observations of cortical microcirculation.
Topics: Acute Disease; Animals; Antipyrine; Autoradiography; Carbon Isotopes; Cerebral Arteries; Cerebral Co | 1970 |
Regional cerebral blood flow in acute apoplexy, including pharmacodynamic studies.
Topics: Acute Disease; Animals; Antipyrine; Autoradiography; Blood Pressure; Carbon Dioxide; Carbon Isotopes | 1968 |