antipyrine has been researched along with Acquired Immunodeficiency Syndrome in 3 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In order to determine the microsomal enzyme activity, the 6-beta-hydroxycortisol/17-hydroxycorticosteroid ratio and antipyrine pharmacokinetic parameters were determined." | 1.30 | Pharmacokinetic interaction of fluconazole and zidovudine in HIV-positive patients. ( Barthel, B; Brockmeyer, NH; Goos, M; Mertins, L; Tillmann, I, 1997) |
| "Antipyrine is a pharmacokinetic model substance to estimate the cytochrome P 450 enzyme activity." | 1.28 | Endogenous interferon plasma levels and antipyrine pharmacokinetics in patients with viral infections. ( Brockmeyer, NH; Goos, M; Mertins, L; Spatz, D; Tillmann, I, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bawdon, RE | 1 |
| Gravell, M | 1 |
| Roberts, S | 1 |
| Hamilton, R | 1 |
| Dax, J | 1 |
| Sever, J | 1 |
| Brockmeyer, NH | 2 |
| Tillmann, I | 2 |
| Mertins, L | 2 |
| Barthel, B | 1 |
| Goos, M | 2 |
| Spatz, D | 1 |
3 other studies available for antipyrine and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Ex vivo human placental transfer of human immunodeficiency virus-1 p24 antigen.
Topics: Acquired Immunodeficiency Syndrome; Antipyrine; Disease Transmission, Infectious; HIV Core Protein p | 1995 |
Pharmacokinetic interaction of fluconazole and zidovudine in HIV-positive patients.
Topics: 17-Hydroxycorticosteroids; Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections | 1997 |
Endogenous interferon plasma levels and antipyrine pharmacokinetics in patients with viral infections.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antipyrine; Female; Humans; Interferons; Male; Radioimmun | 1992 |