antipyrine has been researched along with Ache in 38 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antinociceptive effects of the 2 (each 1000 mg, orally) non-steroidal anti-inflammatory drugs (NSAIDs) acetaminophen (paracetamol) and antipyrine (phenazone) were investigated with a non-inflammatory experimental pain model in 32 healthy volunteers." | 9.07 | Effects of acetaminophen and antipyrine on non-inflammatory pain and EEG activity. ( Bromm, B; Forth, W; Richter, E; Scharein, E, 1992) |
| "In a study including a total of 175 children, ranging in age from 3 months to 3 years and suffering from otitis media, the analgesic effect of alpha-methyl-4-(2-thienylcarbonyl)-phenyl acetic acid (suprofen, Suprol) syrup was compared with that of lidocaine 0." | 9.05 | Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media. ( Michos, N; Stocker, H; Weippl, G, 1985) |
| "Intrathecally administered edaravone, a free radical scavenger, had analgesic effects on inflammatory-induced acute and facilitated pain but not on acute thermal pain, without any behavioural side-effects." | 7.73 | Intrathecal edaravone, a free radical scavenger, is effective on inflammatory-induced pain in rats. ( Nishiyama, T; Ogawa, M, 2005) |
| "NA-3,4-DCM, dosed systemically (intraperitoneally or per os), was capable of interfering with the development of mechanical hypernociception induced by intraplantar injection of carrageenan and complete Freund adjuvant in mice." | 5.36 | N-antipyrine-3, 4-dichloromaleimide, an effective cyclic imide for the treatment of chronic pain: the role of the glutamatergic system. ( Antonialli, CS; Corrêa, R; da Silva, GF; de Campos-Buzzi, F; Filho, VC; Quintão, NL, 2010) |
| "To determine the efficacy of Auralgan otic solution (combination product of antipyrine, benzocaine, and glycerin) compared with an olive oil placebo in the management of moderate to severe ear pain in children with acute otitis media (AOM)." | 5.08 | Efficacy of Auralgan for treating ear pain in children with acute otitis media. ( Hoberman, A; Paradise, JL; Reynolds, EA; Urkin, J, 1997) |
| "Antinociceptive effects of the 2 (each 1000 mg, orally) non-steroidal anti-inflammatory drugs (NSAIDs) acetaminophen (paracetamol) and antipyrine (phenazone) were investigated with a non-inflammatory experimental pain model in 32 healthy volunteers." | 5.07 | Effects of acetaminophen and antipyrine on non-inflammatory pain and EEG activity. ( Bromm, B; Forth, W; Richter, E; Scharein, E, 1992) |
| "In a study including a total of 175 children, ranging in age from 3 months to 3 years and suffering from otitis media, the analgesic effect of alpha-methyl-4-(2-thienylcarbonyl)-phenyl acetic acid (suprofen, Suprol) syrup was compared with that of lidocaine 0." | 5.05 | Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media. ( Michos, N; Stocker, H; Weippl, G, 1985) |
| "Intrathecally administered edaravone, a free radical scavenger, had analgesic effects on inflammatory-induced acute and facilitated pain but not on acute thermal pain, without any behavioural side-effects." | 3.73 | Intrathecal edaravone, a free radical scavenger, is effective on inflammatory-induced pain in rats. ( Nishiyama, T; Ogawa, M, 2005) |
| "The aim of the study was to investigate whether the analgesic effect of propyphenazone (PROP) was increased when it was administered in combination with caffeine (CAFF)." | 2.68 | Analgesic effects of propyphenazone in comparison to its combination with caffeine. ( Hummel, T; Kobal, G; Kraetsch, HG; Kussat, R; Lötsch, J, 1996) |
| "NA-3,4-DCM, dosed systemically (intraperitoneally or per os), was capable of interfering with the development of mechanical hypernociception induced by intraplantar injection of carrageenan and complete Freund adjuvant in mice." | 1.36 | N-antipyrine-3, 4-dichloromaleimide, an effective cyclic imide for the treatment of chronic pain: the role of the glutamatergic system. ( Antonialli, CS; Corrêa, R; da Silva, GF; de Campos-Buzzi, F; Filho, VC; Quintão, NL, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (76.32) | 18.7374 |
| 1990's | 3 (7.89) | 18.2507 |
| 2000's | 3 (7.89) | 29.6817 |
| 2010's | 3 (7.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, HC | 2 |
| Chang, WJ | 1 |
| Kuan, YH | 1 |
| Huang, AC | 2 |
| Shyu, BC | 2 |
| Quintão, NL | 1 |
| da Silva, GF | 1 |
| Antonialli, CS | 1 |
| de Campos-Buzzi, F | 1 |
| Corrêa, R | 1 |
| Filho, VC | 1 |
| RABENALT, H | 1 |
| ARCANGELI, P | 1 |
| GALLETTI, R | 1 |
| FAHRNI, R | 1 |
| Nishiyama, T | 1 |
| Ogawa, M | 1 |
| Saini, AK | 1 |
| Kumar H S, A | 1 |
| Sharma, SS | 1 |
| Brune, K | 1 |
| Niederweis, U | 1 |
| Perlík, F | 1 |
| Roscioni, C | 1 |
| De Ritis, G | 1 |
| De Rossi, P | 1 |
| Diamanti, E | 1 |
| Lauretti, MC | 1 |
| Maggio, F | 1 |
| Marchionni, G | 1 |
| Morabito, F | 1 |
| Kraetsch, HG | 1 |
| Hummel, T | 1 |
| Lötsch, J | 1 |
| Kussat, R | 1 |
| Kobal, G | 1 |
| Hoberman, A | 1 |
| Paradise, JL | 1 |
| Reynolds, EA | 1 |
| Urkin, J | 1 |
| Bromm, B | 1 |
| Forth, W | 1 |
| Richter, E | 1 |
| Scharein, E | 1 |
| Ishikawa, M | 1 |
| Sugawara, S | 1 |
| Takayanagi, Y | 1 |
| Sasaki, K | 1 |
| Rosaschino, F | 1 |
| Cosentina, R | 1 |
| Castelli, F | 1 |
| Milone, V | 1 |
| Bosco, U | 1 |
| Weippl, G | 1 |
| Michos, N | 1 |
| Stocker, H | 1 |
| Tagliavini, R | 1 |
| Lucchelli, PE | 1 |
| Colombi, A | 1 |
| Chiti, W | 1 |
| Ciocia, G | 1 |
| Lagache, G | 1 |
| Depadt, G | 1 |
| Gokhale, VS | 1 |
| Joglekar, GV | 1 |
| Bendre, VV | 1 |
| Gabka, J | 1 |
| Schwietzer, CH | 1 |
| Frankendal, B | 1 |
| Fels, E | 1 |
| Graber, H | 1 |
| Szentmiklósi, P | 1 |
| Krepuska, J | 1 |
| Martens, HL | 2 |
| Melikoglu, S | 1 |
| Vahlensieck, W | 1 |
| Fabian, K | 1 |
| Mörsdorf, K | 1 |
| Gelle, P | 1 |
| Crepin, G | 1 |
| Raymann, F | 1 |
| Faust, B | 1 |
| Kreppel, E | 1 |
| Vogler, H | 1 |
| Kienzler, G | 1 |
| Heynen, U | 1 |
| Schneider, H | 1 |
| Helwing, E | 1 |
| Rhonheimer, C | 1 |
10 trials available for antipyrine and Ache
| Article | Year |
|---|---|
[Clinical evaluation of analgesics].
Topics: Adult; Aged; Analgesics; Antipyrine; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Drug Comb | 1984 |
[Comparison of the clinical activity of 2 analgesic formulations].
Topics: Adult; Analgesics; Antipyrine; Caffeine; Clinical Trials as Topic; Drug Combinations; Female; Humans | 1981 |
Analgesic effects of propyphenazone in comparison to its combination with caffeine.
Topics: Administration, Oral; Adult; Analgesia; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroida | 1996 |
Efficacy of Auralgan for treating ear pain in children with acute otitis media.
Topics: Acute Disease; Adolescent; Adult; Antipyrine; Benzocaine; Child; Child, Preschool; Double-Blind Meth | 1997 |
Effects of acetaminophen and antipyrine on non-inflammatory pain and EEG activity.
Topics: Acetaminophen; Adult; Antipyrine; Double-Blind Method; Electroencephalography; Evoked Potentials, Au | 1992 |
Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Child, Preschool; Drug Combinations; Humans; In | 1985 |
Aspirin and analgin as analgesics.
Topics: Animals; Antipyrine; Aspirin; Clinical Trials as Topic; Female; Humans; Male; Mesylates; Mice; Pain; | 1974 |
[Clinical testing of a new analgesic combination on cancer patients in chronic pain].
Topics: Adult; Aged; Analgesics; Antipyrine; Aspirin; Caffeine; Clinical Trials as Topic; Dextropropoxyphene | 1973 |
[Clinical evaluation of the analgesic effect of Probon].
Topics: Analgesics; Antipyrine; Carboxylic Acids; Clinical Trials as Topic; Codeine; Humans; Methylamines; P | 1971 |
[Clinical examination of Dolo-Tensilan in gynecology].
Topics: Amines; Analgesics; Antipyrine; Dysmenorrhea; Female; Genital Diseases, Female; Humans; Pain; Parasy | 1970 |
28 other studies available for antipyrine and Ache
| Article | Year |
|---|---|
A [14C]iodoantipyrine study of inter-regional correlations of neural substrates following central post-stroke pain in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Carbon Radioisotopes; Cerebral Cortex; | 2015 |
Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain.
Topics: Animals; Antipyrine; Brain Mapping; Humans; Pain; Rats; Stroke; Thalamus | 2016 |
N-antipyrine-3, 4-dichloromaleimide, an effective cyclic imide for the treatment of chronic pain: the role of the glutamatergic system.
Topics: Administration, Oral; Analgesics; Animals; Antipyrine; Behavior, Animal; Carrageenan; Chronic Diseas | 2010 |
[Pain control by commotional].
Topics: Analgesics; Antipyrine; Humans; Hypnotics and Sedatives; Pain; Pain Management | 1953 |
[Effect of pyramidone, ergotamine and codeine on pain sensitivity threshold and on erythralgic reactivity].
Topics: Aminopyrine; Antipyrine; Codeine; Ergot Alkaloids; Ergotamine; Humans; Oxytocics; Pain; Pain Thresho | 1953 |
[Toxic psychoses due to sedormid, saridon and contra-pain].
Topics: Analgesics; Antipyrine; Caffeine; Drug Combinations; Humans; Hypnotics and Sedatives; Pain; Phenacet | 1950 |
Intrathecal edaravone, a free radical scavenger, is effective on inflammatory-induced pain in rats.
Topics: Animals; Antipyrine; Behavior, Animal; Disease Models, Animal; Disinfectants; Dose-Response Relation | 2005 |
Preventive and curative effect of edaravone on nerve functions and oxidative stress in experimental diabetic neuropathy.
Topics: Animals; Antipyrine; Catalase; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Edaravone; Fr | 2007 |
[From willow bark to the coxibs. Development of antiphlogistic analgesics].
Topics: Acetanilides; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Aspirin; Cyc | 2007 |
The effect of endotoxin on nociception in mice.
Topics: Animals; Antipyrine; Benzoquinones; Dose-Response Relationship, Drug; Endotoxins; Male; Mice; Mice, | 1989 |
[A new analgesic in pediatric practice: Sig 8304].
Topics: Adolescent; Analgesics; Antipyrine; Benzoates; Caffeine; Child; Child, Preschool; Drug Combinations; | 1986 |
[Analgesic effect of a corticosteroid for local use].
Topics: Antipyrine; Burns; Clioquinol; Ear Diseases; Female; Flumethasone; Fluorine; Glucocorticoids; Glycol | 1971 |
Pharmacological research on N-methyl-N-antipyrylnicotinamide: synergic and antagonistic effects as to aminopyrine.
Topics: Aminopyrine; Analgesics; Animals; Antipyrine; Chemical Phenomena; Chemistry; Drug Synergism; Edema; | 1972 |
[The value of avafortan in a general surgery service].
Topics: Adult; Aged; Alkanesulfonates; Analgesics; Antipyrine; Ethylamines; Female; Glycine; Humans; Male; M | 1971 |
[Intensification of effect using a combination of analgesic drugs in a split-tablet].
Topics: Analgesics; Antipyrine; Caffeine; Drug Combinations; Humans; Mandelic Acids; Pain; Salicylamides; Sa | 1974 |
[Experiences with Panax, a new phenacetin-free analgesic drug].
Topics: Adolescent; Adult; Aged; Analgesics; Antipyrine; Evaluation Studies as Topic; Female; Headache; Huma | 1973 |
[Experiences with a new neuro analgetic preparation].
Topics: Adult; Aged; Antipyrine; Dosage Forms; Humans; Middle Aged; Pain; Thiamine | 1972 |
[Pain therapy in internal medicine].
Topics: Adult; Aged; Antipyrine; Bromides; Butyrates; Drug Combinations; Female; Humans; Male; Methylamines; | 1972 |
[Induction and control of spasmo-analgesia].
Topics: Analgesics; Antipyrine; Carbachol; Colic; Dioxoles; Humans; Methylamines; Pain; Parasympatholytics; | 1971 |
[Value of Avafortan sugar-coated pills in the treatment of pain in gynecology].
Topics: Antipyrine; Female; Genital Diseases, Female; Glycine; Humans; Methylamines; Pain; Parasympatholytic | 1971 |
[Pain from the viewpoint of the general practitioner. Experiences with a new analgesic].
Topics: Adolescent; Adult; Aged; Amobarbital; Analgesics; Antipyrine; Caffeine; Family Practice; Humans; Mid | 1969 |
[Ambulatory experiences with a new analgesic].
Topics: Adult; Aged; Ambulatory Care; Aminopyrine; Amobarbital; Analgesics; Antipyrine; Caffeine; Female; Hu | 1969 |
[Principles and risks of drug treatment of pain].
Topics: Aminopyrine; Analgesics; Antidepressive Agents; Antipyrine; Aspirin; Codeine; Dibenzazepines; Humans | 1969 |
[Experiences with Dolo-Adamon in orthopedics].
Topics: Analgesics; Antipyrine; Barbiturates; Camphanes; Cinnamates; Codeine; Humans; Methylamines; Orthoped | 1970 |
[Spasmex and Spasmex composition cure spasm, colic and spasmatic pain].
Topics: Adolescent; Adult; Aged; Antipyrine; Colic; Humans; Methylamines; Middle Aged; Nortropanes; Pain; Pa | 1970 |
[Causal therapy of pain states in neurologic diseases].
Topics: Analgesics; Antipyrine; Humans; Methylamines; Nervous System Diseases; Pain; Pyridoxine; Sulfonic Ac | 1970 |
[On the treatment of posttraumatic symptoms].
Topics: Adolescent; Aged; Antipyrine; Dextropropoxyphene; Humans; Pain; Phytotherapy; Plants, Medicinal; Vit | 1968 |
[On the effect of Spondylon in the treatment of painful conditions of the locomotor system].
Topics: Antipyrine; Diphenhydramine; Flavonoids; Humans; Muscular Diseases; Pain | 1968 |