antipyrine has been researched along with AIDS Seroconversion in 2 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antipyrine half-life was significantly reduced (12." | 2.69 | Effect of fusidic acid on the hepatic cytochrome P450 enzyme system. ( Barthel, B; Brockmeyer, NH; Reimann, G; Rockstroh, JK; Spatz, D, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schooley, RT | 1 |
| Campbell, TB | 1 |
| Kuritzkes, DR | 1 |
| Blaschke, T | 1 |
| Stein, DS | 1 |
| Rosandich, ME | 1 |
| Phair, J | 1 |
| Pottage, JC | 1 |
| Messari, F | 1 |
| Collier, A | 1 |
| Kahn, J | 1 |
| Reimann, G | 1 |
| Barthel, B | 1 |
| Rockstroh, JK | 1 |
| Spatz, D | 1 |
| Brockmeyer, NH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pharmacokinetic Study of L-697,661 Alone and in Combination With Zidovudine[NCT00000628] | Phase 1 | 27 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for antipyrine and AIDS Seroconversion
| Article | Year |
|---|---|
Phase 1 study of combination therapy with L-697,661 and zidovudine. The ACTG 184 Protocol Team.
Topics: Adult; Antipyrine; Antiviral Agents; Base Sequence; Benzoxazoles; Cross-Over Studies; DNA Primers; D | 1996 |
Effect of fusidic acid on the hepatic cytochrome P450 enzyme system.
Topics: Anti-Bacterial Agents; Antipyrine; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Sys | 1999 |