antimony-sodium-gluconate and Leg-Ulcer

Topics: Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Azure Stains; Biopsy; Humans; Leg Ulcer; Leishmania; Leishmaniasis, Cutaneous; Male; Meglumine; Meglumine Antimoniate; Middle Aged; Organometallic Compounds; Travel

Cutaneous South American leishmaniasis is caused by several species of leishmaniasis. Lack of appropriate treatment may lead to mucocutaneous leishmaniasis, mainly with L. b. braziliensis and L. b. panamensis.. To describe the clinical findings of Israeli travelers infected with cutaneous South American leishmaniasis and to draw attention to this problem.. Ten patients were interviewed, examined and treated.. Twenty-two lesions of cutaneous leishmaniasis were found, all in exposed areas. Patients were seen by an average three physicians (range 1-6) before the final diagnosis was confirmed by direct smear, after an average period of 125 days (range 88-270 days). Treatment with Pentostam was started after an average period of 134 days (range 94-275 days). All lesions healed completely, but with scarring.. Travelers to endemic areas, as well as physicians, should be instructed about the potential risks and the clinical manifestations of cutaneous and mucocutaneous South American leishmaniasis. Such awareness will prevent undue delay in diagnosis and treatment.

Topics: Adult; Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Female; Headache; Humans; Israel; Leg Ulcer; Leishmania mexicana; Leishmaniasis, Cutaneous; Liver; Liver Function Tests; Male; Meglumine; Meglumine Antimoniate; Muscle Weakness; Muscular Diseases; Organometallic Compounds; Pain; Retrospective Studies; Skin; South America; Travel; Weight Loss

Topics: Adult; Antimony Sodium Gluconate; Humans; Leg Ulcer; Leishmaniasis, Mucocutaneous; Male; Peru