antimony-sodium-gluconate and Eyelid-Diseases

A 61-year-old man presented with erysipelas-like cutaneous leishmaniasis.

Topics: Antimony Sodium Gluconate; Antiprotozoal Agents; Cellulitis; Diagnosis, Differential; Disease Progression; DNA, Protozoan; Endemic Diseases; Erysipelas; Eyelid Diseases; Facial Dermatoses; Humans; Hypokalemia; Leishmania donovani; Leishmaniasis, Cutaneous; Long QT Syndrome; Male; Middle Aged; Pancytopenia; Spain; Travel

A 50 year-old man, a United States resident, presented in Texas with a violaceous non-ulcerating lesion, involving the entire lower eyelid. The patient had traveled to a jungle area of Belize several hours drive from the capital city. Leishmania mexicana was isolated. The lesion only partially resolved after an initial course of sodium stibogluconate, requiring retreatment. At two years of follow-up, there was no relapse. The parasite isolated from the patient caused a progressive, non-ulcerating lesion in an experimental mouse footpad infection. This is an unusual case of cutaneous leishmaniasis in a traveler. Travelers must be educated about personal protective measures to prevent exotic infections acquired during travel.

Topics: Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Belize; Eyelid Diseases; Humans; Leishmania mexicana; Leishmaniasis, Cutaneous; Male; Middle Aged; Travel; Treatment Outcome

A 50 year-old man, a United States resident, presented in Texas with a violaceous non-ulcerating lesion, involving the entire lower eyelid. The patient had traveled to a jungle area of Belize several hours drive from the capital city. Leishmania mexicana was isolated. The lesion only partially resolved after an initial course of sodium stibogluconate, requiring retreatment. At two years of follow-up, there was no relapse. The parasite isolated from the patient caused a progressive, non-ulcerating lesion in an experimental mouse footpad infection. This is an unusual case of cutaneous leishmaniasis in a traveler. Travelers must be educated about personal protective measures to prevent exotic infections acquired during travel.

Topics: Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Belize; Eyelid Diseases; Humans; Itraconazole; Leishmania mexicana; Leishmaniasis, Cutaneous; Male; Middle Aged; Travel

A patient with chronic progressive external ophthalmoplegia contracted cutaneous leishmaniasis of the upper eyelid. Infection of this site is rare because eyelid movements usually prevent the sandfly vector from biting the skin there. It is postulated that the relative immobility of the upper eyelid in this patient was a major predisposing factor for the infection.

Topics: Antimony Sodium Gluconate; Blepharoptosis; Eyelid Diseases; Female; Humans; Leishmaniasis, Mucocutaneous; Middle Aged; Ophthalmoplegia