antimony-sodium-gluconate and Epistaxis

Mucosal leishmaniasis (ML) is associated with progressive tissue destruction and granuloma formation, often after a considerable period of latency from an initial cutaneous infection. We report a case of recurrent epistaxis of 3 years duration and nasopharyngeal obstruction in a woman with treated cutaneous leishmaniasis nearly 30 years before and with no further exposure to Leishmania. Computed tomography revealed nasal septal perforation and histopathology demonstrated chronic inflammation. Microscopy was negative for amastigotes, but molecular testing of nasal mucosa biopsy detected

Topics: Adult; Antimony Sodium Gluconate; Antiprotozoal Agents; Diagnosis, Differential; Epistaxis; Female; Humans; Inflammation; Leishmania braziliensis; Leishmaniasis, Mucocutaneous; Nasal Mucosa; Nasal Septal Perforation; Nasal Septum; Parasite Load; Peru; Time Factors; Tomography, X-Ray Computed