antimony-sodium-gluconate and Blindness

Visceral leishmaniasis (VL) is an important cause of morbidity and mortality that affects multiple organs. Post-kala-azar ocular involvement is a serious complication that can manifest as blepharo-conjuctivitis or pan-uveitis. Failure of prompt diagnosis and treatment can result in blindness. We report five cases with pan-uveitis that followed the successful treatment of VL and consequent post-kala-azar dermal leishmaniasis were presented. Two patients lost their sight permanently but the rest were successfully treated. A high index of suspicion and prompt treatment are of paramount importance in order to avoid blindness following post-kala-azar ocular uveitis.

Topics: Adolescent; Adult; Antimony Sodium Gluconate; Antiprotozoal Agents; Blindness; Child; Eye Infections, Parasitic; Female; Humans; Leishmania; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Male; Panuveitis