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anthranilic acid and Inflammation

anthranilic acid has been researched along with Inflammation in 13 studies

anthranilic acid: RN given refers to parent cpd; structure in Negwer, 5th ed, #565
anthranilic acid : An aminobenzoic acid that is benzoic acid having a single amino substituent located at position 2. It is a metabolite produced in L-tryptophan-kynurenine pathway in the central nervous system.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"Healthy young adults (n = 737) aged 18-28 y without any known diseases or clinical evidence of inflammation provided blood samples for analysis of serum tryptophan/kynurenine metabolites, neopterin, C-reactive protein (CRP), and plasma pyridoxal 5'-phosphate (PLP) with LC-tandem mass spectrometry methodologies."3.83Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults. ( Brody, LC; Deac, OM; Fan, R; Gardiner, CM; Lu, Z; McCann, A; Meyer, K; Midttun, Ø; Mills, JL; Molloy, AM; Quinn, L; Shane, B; Ueland, PM, 2016)
"Circulating neopterin and kynurenine/tryptophan ratio (KTR) increase during inflammation and serve as markers of cellular immune activation, but data are sparse on other determinants of these markers and metabolites of the kynurenine pathway."3.79A community-based study on determinants of circulating markers of cellular immune activation and kynurenines: the Hordaland Health Study. ( Eussen, SJ; Midttun, Ø; Nygård, O; Tell, GS; Theofylaktopoulou, D; Ueland, PM; Ulvik, A; Vollset, SE, 2013)
" In contrast, resolution of inflammation coincided with the decreased concentration of tryptophan and accumulation of its catabolites: kynurenine, anthranilic acid, and 3-hydroxyanthranilic acid in lymph nodes but not in the spleen."3.78An exploratory study of the interplay between decreased concentration of tryptophan, accumulation of kynurenines, and inflammatory arthritis. ( Kolodziej, L, 2012)
"Anthranilic acid (AA) is a tryptophan-derived uremic toxin with multidirectional properties that can affect the hemostatic system."1.48Association between uremic toxin-anthranilic acid and fibrinolytic system activity in predialysis patients at different stages of chronic kidney disease. ( Grzegorzewski, W; Kaminski, TW; Karbowska, M; Kuna, J; Mysliwiec, M; Pawlak, D; Pawlak, K, 2018)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaminski, TW1
Pawlak, K1
Karbowska, M1
Mysliwiec, M1
Grzegorzewski, W1
Kuna, J1
Pawlak, D1
Badawy, AA1
Theofylaktopoulou, D1
Midttun, Ø2
Ulvik, A1
Ueland, PM2
Tell, GS1
Vollset, SE1
Nygård, O1
Eussen, SJ1
Deac, OM1
Mills, JL1
Gardiner, CM1
Shane, B1
Quinn, L1
McCann, A1
Meyer, K1
Fan, R1
Lu, Z1
Brody, LC1
Molloy, AM1
Birner, A1
Platzer, M1
Bengesser, SA1
Dalkner, N1
Fellendorf, FT1
Queissner, R1
Pilz, R1
Rauch, P1
Maget, A1
Hamm, C1
Herzog-Eberhard, S1
Mangge, H1
Fuchs, D1
Moll, N1
Zelzer, S1
Schütze, G1
Schwarz, M1
Reininghaus, B1
Kapfhammer, HP1
Reininghaus, EZ1
Backhaus, C1
Rahman, H1
Scheffler, S1
Laatsch, H1
Hardeland, R1
Kolodziej, L1
WINDER, CV3
WAX, J3
SCOTTI, L1
SCHERRER, RA1
JONES, EM2
SHORT, FW1
SERRANO, B1
McPHEE, ML1
BOSTROEM, H1
BERNTSEN, K1
WHITEHOUSE, MW1
DELBARRE, F1
BUU HOUI, NP1
KAHAN, A1
JACQUIGNON, P1
BROUILHET, H1
MARTY, M1
PERIN, F1
TABONE, J1
JACOBELLI, G1
WELFORD, M1

Other Studies

13 other studies available for anthranilic acid and Inflammation

ArticleYear
Association between uremic toxin-anthranilic acid and fibrinolytic system activity in predialysis patients at different stages of chronic kidney disease.
    International urology and nephrology, 2018, Volume: 50, Issue:1

    Topics: Adult; Aged; alpha-2-Antiplasmin; Biomarkers; Case-Control Studies; Female; Fibrinolysin; Fibrinolys

2018
Hypothesis kynurenic and quinolinic acids: The main players of the kynurenine pathway and opponents in inflammatory disease.
    Medical hypotheses, 2018, Volume: 118

    Topics: Animals; Anti-Inflammatory Agents; Humans; Immunosuppressive Agents; Inflammation; Kynurenic Acid; K

2018
A community-based study on determinants of circulating markers of cellular immune activation and kynurenines: the Hordaland Health Study.
    Clinical and experimental immunology, 2013, Volume: 173, Issue:1

    Topics: 3-Hydroxyanthranilic Acid; Aged; Aging; Biomarkers; Body Mass Index; Creatinine; Female; Humans; Inf

2013
Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults.
    The Journal of nutrition, 2016, Volume: 146, Issue:9

    Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Cross

2016
Increased breakdown of kynurenine towards its neurotoxic branch in bipolar disorder.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Adult; Bipolar Disorder; Brain; Case-Control Studies; Cognition; Depression; Female; Humans; Inflamm

2017
NO scavenging by 3-hydroxyanthranilic acid and 3-hydroxykynurenine: N-nitrosation leads via oxadiazoles to o-quinone diazides.
    Nitric oxide : biology and chemistry, 2008, Volume: 19, Issue:3

    Topics: 3-Hydroxyanthranilic Acid; Acetylcysteine; Aminophenols; Chromatography, Thin Layer; Diazonium Compo

2008
An exploratory study of the interplay between decreased concentration of tryptophan, accumulation of kynurenines, and inflammatory arthritis.
    IUBMB life, 2012, Volume: 64, Issue:12

    Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Arthritis, Experimental;

2012
Anti-inflammatory, antipyretic and antinociceptive properties of N-(2,3-xylyl)anthranilic acid (mefenamic acid).
    The Journal of pharmacology and experimental therapeutics, 1962, Volume: 138

    Topics: Analgesics; Anaphylaxis; Anti-Inflammatory Agents; Antipyretics; Humans; Inflammation; Mefenamic Aci

1962
Anti-inflammatory and antipyretic properties of N-(alpha,alpha,alpha-trifluoro-m-tolyl) anthranilic acid (CI-440; flufenamic acid).
    Arthritis and rheumatism, 1963, Volume: 6

    Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Body Temperature; Eryt

1963
BIOCHEMICAL PROPERTIES OF ANTI-INFLAMMATORY DRUGS-II. SOME EFFECTS ON SULPHATE-35S METABOLISM IN VIVO.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Adenosine Triphosphate; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antipyrine; Autoradio

1964
[NON-STEROID, ANTI-INFLAMMATORY SUBSTANCES. II. N-(FLUOROPHENYL) ANTHRANILIC ACIDS].
    Medicina experimentalis : International journal of experimental medicine, 1964, Volume: 11

    Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Edema; Inflammation; K

1964
[INTERVENTION OF ANTI-INFLAMMATORY AGENTS IN THE TRANSGLUCOSIDATION PHENOMENA LINKED TO URIDINE DIPHOSPHATE GLUCOSE].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1965, Jan-11, Volume: 260

    Topics: Anti-Inflammatory Agents; Bacillus megaterium; Cortisone; Enzyme Inhibitors; Glucosyltransferases; H

1965
ANTI-INFLAMMATORY AND ANTIPYRETIC PROPERTIES OF N-(2,6-DICHLORO-M-TOLYL)ANTHRANILIC ACID (CI-583).
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 148

    Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Aspirin;

1965