anthranilic acid has been researched along with Alzheimer Disease in 3 studies
anthranilic acid: RN given refers to parent cpd; structure in Negwer, 5th ed, #565
anthranilic acid : An aminobenzoic acid that is benzoic acid having a single amino substituent located at position 2. It is a metabolite produced in L-tryptophan-kynurenine pathway in the central nervous system.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The kynurenine pathway (KP) is a major route of tryptophan metabolism." | 1.36 | Kynurenine and its metabolites in Alzheimer's disease patients. ( Bien, B; Gulaj, E; Pawlak, D; Pawlak, K, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Fathi, M | 1 |
| Vakili, K | 1 |
| Yaghoobpoor, S | 1 |
| Tavasol, A | 1 |
| Jazi, K | 1 |
| Hajibeygi, R | 1 |
| Shool, S | 1 |
| Sodeifian, F | 1 |
| Klegeris, A | 1 |
| McElhinney, A | 1 |
| Tavirani, MR | 1 |
| Sayehmiri, F | 1 |
| Paul, A | 1 |
| Nadimpally, KC | 1 |
| Mondal, T | 1 |
| Thalluri, K | 1 |
| Mandal, B | 1 |
| Gulaj, E | 1 |
| Pawlak, K | 1 |
| Bien, B | 1 |
| Pawlak, D | 1 |
1 review available for anthranilic acid and Alzheimer Disease
| Article | Year |
|---|---|
Dynamic changes in metabolites of the kynurenine pathway in Alzheimer's disease, Parkinson's disease, and Huntington's disease: A systematic Review and meta-analysis.
Topics: 3-Hydroxyanthranilic Acid; Adenosine; Alzheimer Disease; Humans; Huntington Disease; Hydroxyindoleac | 2022 |
2 other studies available for anthranilic acid and Alzheimer Disease
| Article | Year |
|---|---|
Inhibition of Alzheimer's amyloid-β peptide aggregation and its disruption by a conformationally restricted α/β hybrid peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Circular Dichroism; Humans; Microscopy, Electron, Transmis | 2015 |
Kynurenine and its metabolites in Alzheimer's disease patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Female; Humans; Ky | 2010 |