Page last updated: 2024-10-22

anthralin and Inflammation

anthralin has been researched along with Inflammation in 15 studies

Anthralin: An anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.
anthralin : An anthracene compound derived by the substitution of -OH groups for hydrogen at C-1 and C-8, and with an oxo group at C-9.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"1 The effect of topical arachidonic acid on anthralin inflammation was studied using sequential measurements of erythema (reflectance photometry) and oedema (calipers)."7.67Effect of arachidonic acid on anthralin inflammation. ( Lawrence, CM; Shuster, S, 1987)
"1 The effect of topical arachidonic acid on anthralin inflammation was studied using sequential measurements of erythema (reflectance photometry) and oedema (calipers)."3.67Effect of arachidonic acid on anthralin inflammation. ( Lawrence, CM; Shuster, S, 1987)
"Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare and chronic skin disorder, which may trouble the patient considerably."2.67Treatment of inflammatory linear verrucous epidermal nevus. ( Rulo, HF; van de Kerkhof, PC, 1991)
"Psoriasis is a common, immune-mediated inflammatory skin disease characterized by red, heavily scaled plaques."1.42Exploring the mode of action of dithranol therapy for psoriasis: a metabolomic analysis using HaCaT cells. ( Broadhurst, D; Dunn, WB; Goodacre, R; Griffiths, CE; Hollywood, KA; Winder, CL; Xu, Y, 2015)
"Dithranol has been used to treat psoriasis for decades."1.33Dithranol abolishes UCH-L1 immunoreactivity in the nerve fibers of the rat orofacial skin. ( Dobo, E; Gulya, K; Orojan, I; Szigeti, C; Varszegi, S, 2006)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19905 (33.33)18.7374
1990's5 (33.33)18.2507
2000's3 (20.00)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Hollywood, KA1
Winder, CL1
Dunn, WB1
Xu, Y1
Broadhurst, D1
Griffiths, CE1
Goodacre, R1
Gábor, M1
Orojan, I1
Szigeti, C1
Varszegi, S1
Dobo, E1
Gulya, K1
Van der Vleuten, CJ1
Gerritsen, MJ1
De Jong, EM1
Elbers, M1
De Jongh, GJ1
van de Kerkhof, PC3
La, E1
Muga, SJ1
Locniskar, MF1
Fischer, SM1
Messer, G1
Rupec, RA1
Viluksela, M1
Rulo, HF1
Queille-Roussel, C1
Duteil, L1
de Mare, S1
Happle, R1
Whitefield, M1
Leeder, GM1
Mosedale, AR1
Black, AK1
Barr, RM1
Wong, E1
Brain, S1
Greaves, MW1
Dickinson, R1
Shroot, B1
Hensby, CN1
Lawrence, CM1
Shuster, S1
Gawkrodger, DJ1
Carr, MM1
McVittie, E1
Guy, K1
Hunter, JA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Formulation and Clinical Evaluation of Ethosomal and Liposomal Preparations of Anthralin in Psoriasis[NCT03348462]Phase 420 participants (Actual)Interventional2017-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for anthralin and Inflammation

ArticleYear
Models of acute inflammation in the ear.
    Methods in molecular biology (Clifton, N.J.), 2003, Volume: 225

    Topics: Alkynes; Animals; Anthralin; Arachidonic Acid; Cantharidin; Capsaicin; Carrageenan; Croton Oil; Derm

2003
[Induced inflammation in normal human skin. I. Value, methods and results].
    Annales de dermatologie et de venereologie, 1991, Volume: 118, Issue:4

    Topics: Anthralin; Croton Oil; Dermatitis; Drug Hypersensitivity; Humans; Inflammation; Skin Diseases; Skin

1991

Trials

3 trials available for anthralin and Inflammation

ArticleYear
A novel dithranol formulation (Micanol): the effects of monotherapy and UVB combination therapy on epidermal differentiation, proliferation and cutaneous inflammation in psoriasis vulgaris.
    Acta dermato-venereologica, 1996, Volume: 76, Issue:5

    Topics: Adult; Aged; Anthralin; Capsules; Cell Differentiation; Cell Division; Epidermis; Female; Humans; Im

1996
Treatment of inflammatory linear verrucous epidermal nevus.
    Dermatologica, 1991, Volume: 182, Issue:2

    Topics: Adolescent; Anthralin; Female; Humans; Inflammation; Isotretinoin; Nevus; Skin Neoplasms

1991
Keratinocyte expression of MHC class II antigens in allergic sensitization and challenge reactions and in irritant contact dermatitis.
    The Journal of investigative dermatology, 1987, Volume: 88, Issue:1

    Topics: Anthralin; Dermatitis, Contact; Dinitrochlorobenzene; Female; Histocompatibility Antigens Class II;

1987

Other Studies

10 other studies available for anthralin and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Exploring the mode of action of dithranol therapy for psoriasis: a metabolomic analysis using HaCaT cells.
    Molecular bioSystems, 2015, Volume: 11, Issue:8

    Topics: Anthralin; Cell Line; Cell Proliferation; Gas Chromatography-Mass Spectrometry; Humans; Inflammation

2015
Dithranol abolishes UCH-L1 immunoreactivity in the nerve fibers of the rat orofacial skin.
    Brain research, 2006, Nov-22, Volume: 1121, Issue:1

    Topics: Animals; Anthralin; Dermatologic Agents; Face; Humans; Image Processing, Computer-Assisted; Inflamma

2006
Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis.
    Molecular carcinogenesis, 1999, Volume: 24, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcino

1999
[Nuclear factor kappa B (NF-kappa B). II. Pathophysiologic meaning].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2001, Volume: 52, Issue:8

    Topics: Acute-Phase Reaction; Administration, Topical; Animals; Anthralin; Anti-Inflammatory Agents; Autoimm

2001
Characteristics and modulation of dithranol (anthralin)-induced skin irritation in the mouse ear model.
    Archives of dermatological research, 1991, Volume: 283, Issue:4

    Topics: Administration, Topical; Adrenal Cortex Hormones; Animals; Anthralin; Anti-Inflammatory Agents, Non-

1991
Dithranol in the treatment of inflammatory linear verrucous epidermal nevus.
    Acta dermato-venereologica, 1989, Volume: 69, Issue:1

    Topics: Adult; Anthralin; Humans; Inflammation; Male; Nevus; Skin Neoplasms

1989
Inhibition of dithranol inflammation by free-radical scavengers.
    Lancet (London, England), 1985, Jan-19, Volume: 1, Issue:8421

    Topics: Anthracenes; Anthralin; Inflammation; Vitamin E

1985
Lipoxygenase products of arachidonic acid in human inflamed skin.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:3

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adult; Anthralin; Arachidonic Acid; Arachidonic Acids; D

1985
Effect of arachidonic acid on anthralin inflammation.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:2

    Topics: Administration, Topical; Adult; Aged; Anthralin; Arachidonic Acid; Arachidonic Acids; Diterpenes; Ed

1987