Page last updated: 2024-10-22

anthralin and Hyperplasia

anthralin has been researched along with Hyperplasia in 8 studies

Anthralin: An anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.
anthralin : An anthracene compound derived by the substitution of -OH groups for hydrogen at C-1 and C-8, and with an oxo group at C-9.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
" Although dose-response comparisons indicated that chrysarobin was several orders of magnitude less potent than TPA for promoting papilloma formation, this anthrone was 1."1.27Mechanism of mouse skin tumor promotion by chrysarobin. ( Aalfs, KK; Cantor, J; Coombs, MM; Decina, PC; DiGiovanni, J; Prichett, WP, 1985)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Klein-Szanto, AJ2
Major, SK1
Slaga, TJ2
La, E1
Muga, SJ1
Locniskar, MF1
Fischer, SM1
Viluksela, M2
Kosma, VM3
Männistö, PT1
Hanhijärvi, H1
Collan, Y2
Naukkarinen, A1
Aalto, ML1
Männistö, P1
DiGiovanni, J1
Decina, PC1
Prichett, WP1
Cantor, J1
Aalfs, KK1
Coombs, MM1

Other Studies

8 other studies available for anthralin and Hyperplasia

ArticleYear
Quantitative evaluation of dark keratinocytes induced by several promoting and hyperplasiogenic agents: their use as an early morphological indicator of tumor-promoting action.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Alkynes; Anthralin; Calcimycin; Carcinogens; Diterpenes; Epidermal Cells; Epidermis; Hyperplasia; Ke

1982
Numerical variation of dark cells in normal and chemically induced hyperplastic epidermis with age of animal and efficiency of tumor promoter.
    Cancer research, 1981, Volume: 41, Issue:11 Pt 1

    Topics: Administration, Topical; Age Factors; Alkynes; Animals; Anthralin; Calcimycin; Carcinogens; Epidermi

1981
Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis.
    Molecular carcinogenesis, 1999, Volume: 24, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcino

1999
Dithranol (anthralin)-induced skin irritation in C57BL/6, NMRI and SENCAR mice.
    Pharmacology & toxicology, 1991, Volume: 69, Issue:2

    Topics: Animals; Anthralin; Dermatitis, Contact; Dose-Response Relationship, Drug; Edema; Female; Hyperplasi

1991
Characteristics and modulation of dithranol (anthralin)-induced skin irritation in the mouse ear model.
    Archives of dermatological research, 1991, Volume: 283, Issue:4

    Topics: Administration, Topical; Adrenal Cortex Hormones; Animals; Anthralin; Anti-Inflammatory Agents, Non-

1991
A 6-month dermal toxicity test with dithranol and butantrone in miniature swine.
    Contact dermatitis, 1986, Volume: 15, Issue:1

    Topics: Administration, Topical; Animals; Anthralin; Drug Eruptions; Drug Evaluation, Preclinical; Female; G

1986
Histopathological and morphometrical analysis applied to skin changes in NMRI mice induced by dithranol (anthranil) and its acyl analogs.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1986, Volume: 9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Cell Nucleus; DNA; Female; Hyperplasia; Mice;

1986
Mechanism of mouse skin tumor promotion by chrysarobin.
    Cancer research, 1985, Volume: 45, Issue:6

    Topics: Animals; Anthracenes; Anthralin; Carcinogens; Dose-Response Relationship, Drug; Edema; Female; Hyper

1985