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antazoline and Status Epilepticus

antazoline has been researched along with Status Epilepticus in 1 studies

Antazoline: An antagonist of histamine H1 receptors.
antazoline : A member of the class of imidazolines that is 2-aminomethyl-2-imidazoline in which the exocyclic amino hydrogens are replaced by benzyl and phenyl groups. Antazoline is only found in individuals that have taken the drug.

Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)

Research Excerpts

ExcerptRelevanceReference
" Here, we investigated the effects of antazoline on NMDA toxicity and current in rat hippocampal neuronal cultures, and on an in vivo model of status epilepticus."7.72Neuroprotective activity of antazoline against neuronal damage induced by limbic status epilepticus. ( Bockaert, J; Lafon-Cazal, M; Lerner-Natoli, M; Milhaud, D; Rondouin, G, 2003)
" Here, we investigated the effects of antazoline on NMDA toxicity and current in rat hippocampal neuronal cultures, and on an in vivo model of status epilepticus."3.72Neuroprotective activity of antazoline against neuronal damage induced by limbic status epilepticus. ( Bockaert, J; Lafon-Cazal, M; Lerner-Natoli, M; Milhaud, D; Rondouin, G, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Milhaud, D1
Rondouin, G1
Lerner-Natoli, M1
Bockaert, J1
Lafon-Cazal, M1

Other Studies

1 other study available for antazoline and Status Epilepticus

ArticleYear
Neuroprotective activity of antazoline against neuronal damage induced by limbic status epilepticus.
    Neuroscience, 2003, Volume: 120, Issue:2

    Topics: Animals; Animals, Newborn; Antazoline; Cell Count; Cells, Cultured; Cerebral Cortex; Disease Models,

2003