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antazoline and Hypersensitivity

antazoline has been researched along with Hypersensitivity in 13 studies

Antazoline: An antagonist of histamine H1 receptors.
antazoline : A member of the class of imidazolines that is 2-aminomethyl-2-imidazoline in which the exocyclic amino hydrogens are replaced by benzyl and phenyl groups. Antazoline is only found in individuals that have taken the drug.

Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.

Research Excerpts

ExcerptRelevanceReference
" Evaluation of response at various times after instillation of medication for lacrimation, conjunctival inflammation, pruritus, photophobia and pain showed naphazoline hydrochloride, antazoline phosphate and the combination product superior to placebo."9.04Antazoline phosphate and naphazoline hydrochloride, singly and in combination for the treatment of allergic conjunctivitis-a controlled, double-blind clinical trial. ( Miller, J; Wolf, EH, 1975)
"A case of repeated antazoline-induced immune hemolytic anemia, thrombocytopenia, hemoglobinuria, and acute renal failure is reported."7.65Antazoline-induced immune hemolytic anemia, hemoglobinuria, and acute renal failure. ( Ahlstedt, S; Aurell, M; Bengtsson, U; Kaijser, B, 1975)
" Evaluation of response at various times after instillation of medication for lacrimation, conjunctival inflammation, pruritus, photophobia and pain showed naphazoline hydrochloride, antazoline phosphate and the combination product superior to placebo."5.04Antazoline phosphate and naphazoline hydrochloride, singly and in combination for the treatment of allergic conjunctivitis-a controlled, double-blind clinical trial. ( Miller, J; Wolf, EH, 1975)
"A case of repeated antazoline-induced immune hemolytic anemia, thrombocytopenia, hemoglobinuria, and acute renal failure is reported."3.65Antazoline-induced immune hemolytic anemia, hemoglobinuria, and acute renal failure. ( Ahlstedt, S; Aurell, M; Bengtsson, U; Kaijser, B, 1975)
" The three preparations were found to vary greatly in patient comfort and acceptability but were not different in their ability to ameliorate the itching, tearing, redness, edema and discomfort when dosed topically for the relief of allergic conjunctivitis."2.65A double-masked comparison of ocular decongestants as therapy for allergic conjunctivitis. ( deFaller, JM; Lanier, BQ; Smith, JP; Tremblay, N, 1983)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199011 (84.62)18.7374
1990's2 (15.38)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Menciu, C1
Duflos, M1
Fouchard, F1
Le Baut, G1
Emig, P1
Achterrath, U1
Szelenyi, I1
Nickel, B1
Schmidt, J1
Kutscher, B1
Günther, E1
HURWITZ, P1
PIPKORN, U1
GRANDJEAN, LC2
ACKROYD, JF1
KMONICEK, J1
JOSEPH, H1
Lanier, BQ1
Tremblay, N1
Smith, JP1
deFaller, JM1
Piłatowa, M1
Zawadowski, J1
Zawisza, E1
Srenger, Z1
Miller, J1
Wolf, EH1
Bengtsson, U1
Ahlstedt, S1
Aurell, M1
Kaijser, B1

Trials

3 trials available for antazoline and Hypersensitivity

ArticleYear
A double-masked comparison of ocular decongestants as therapy for allergic conjunctivitis.
    Annals of allergy, 1983, Volume: 50, Issue:3

    Topics: Antazoline; Clinical Trials as Topic; Conjunctivitis; Double-Blind Method; Female; Humans; Hypersens

1983
[Nospilin in the treatment of chronic allergic inflammatory conditions of palpebral margins and conjunctivae (author's transl)].
    Klinika oczna, 1980, Volume: 82, Issue:8

    Topics: Antazoline; Blepharitis; Chronic Disease; Clinical Trials as Topic; Conjunctivitis; Drug Combination

1980
Antazoline phosphate and naphazoline hydrochloride, singly and in combination for the treatment of allergic conjunctivitis-a controlled, double-blind clinical trial.
    Annals of allergy, 1975, Volume: 35, Issue:2

    Topics: Adolescent; Adult; Aged; Antazoline; Child; Clinical Trials as Topic; Conjunctivitis; Drug Combinati

1975

Other Studies

10 other studies available for antazoline and Hypersensitivity

ArticleYear
New N-(pyridin-4-yl)-(indol-3-yl)acetamides and propanamides as antiallergic agents.
    Journal of medicinal chemistry, 1999, Feb-25, Volume: 42, Issue:4

    Topics: Acetylcholine; Animals; Anti-Allergic Agents; Bronchoalveolar Lavage; Capillary Permeability; Carbac

1999
Antistine in ocular allergy.
    American journal of ophthalmology, 1948, Volume: 31, Issue:11

    Topics: Anaphylaxis; Antazoline; Eye; Head; Hypersensitivity; Imidazoles

1948
[Water metabolism of allergic patients and its response to antistine].
    Acta allergologica, 1953, Volume: 6, Issue:1

    Topics: Antazoline; Anti-Allergic Agents; Histamine H1 Antagonists; Hypersensitivity; Immune System Diseases

1953
[Allergic thrombopenic purpura caused by antistine (imidamini chloridum)].
    Ugeskrift for laeger, 1956, Jul-12, Volume: 118, Issue:28

    Topics: Antazoline; Histamine H1 Antagonists; Humans; Hypersensitivity; Immune System Diseases; Purpura; Pur

1956
[Allergic thrombopenic purpura caused by antistine (imidamini chloridum)].
    Ugeskrift for laeger, 1956, Jul-12, Volume: 118, Issue:28

    Topics: Antazoline; Histamine H1 Antagonists; Humans; Hypersensitivity; Immune System Diseases; Purpura; Pur

1956
[Allergic thrombopenic purpura caused by antistine (imidamini chloridum)].
    Ugeskrift for laeger, 1956, Jul-12, Volume: 118, Issue:28

    Topics: Antazoline; Histamine H1 Antagonists; Humans; Hypersensitivity; Immune System Diseases; Purpura; Pur

1956
[Allergic thrombopenic purpura caused by antistine (imidamini chloridum)].
    Ugeskrift for laeger, 1956, Jul-12, Volume: 118, Issue:28

    Topics: Antazoline; Histamine H1 Antagonists; Humans; Hypersensitivity; Immune System Diseases; Purpura; Pur

1956
Thrombocytopenic purpura due to hypersensitivity to the antihistaminic drug antazoline (2 (n-phenyl-n-benzyl-amino-methyl) imidazoline) (abstract).
    Le Sang, 1955, Volume: 26, Issue:1

    Topics: Antazoline; Anti-Allergic Agents; Histamine H1 Antagonists; Humans; Hypersensitivity; Imidazolines;

1955
[Prevention of ocular anaphylactic reaction with antistine and novocaine].
    Ceskoslovenska oftalmologie, 1950, Volume: 6, Issue:6

    Topics: Anaphylaxis; Antazoline; Eye; Histamine Antagonists; Hypersensitivity; Immune System Diseases; Proca

1950
[Prevention of sero-anaphylactic shock in rabbit used for bio-diagnosis of pregnancy by antistine and skeptophylaxis].
    Revue d'immunologie et de therapie antimicrobienne, 1951, Volume: 15, Issue:4

    Topics: Anaphylaxis; Animals; Antazoline; Biomedical Research; Female; Humans; Hypersensitivity; Immune Syst

1951
[A case of allergic reaction to the sting by the bee].
    Otolaryngologia polska = The Polish otolaryngology, 1993, Volume: 47, Issue:6

    Topics: Adult; Antazoline; Epinephrine; Female; Humans; Hydrocortisone; Hypersensitivity; Insect Bites and S

1993
[A combined treatment of allergic conjunctivitis (author's transl)].
    Lijecnicki vjesnik, 1976, Volume: 98, Issue:1

    Topics: Administration, Topical; Adolescent; Adult; Aged; Antazoline; Anti-Inflammatory Agents; Ascorbic Aci

1976
Antazoline-induced immune hemolytic anemia, hemoglobinuria, and acute renal failure.
    Acta medica Scandinavica, 1975, Volume: 198, Issue:3

    Topics: Acute Kidney Injury; Anemia, Hemolytic, Autoimmune; Antazoline; Blood Cell Count; Blood Platelets; C

1975