Page last updated: 2024-08-24

anisodamine and Shock, Septic

anisodamine has been researched along with Shock, Septic in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199016 (57.14)18.7374
1990's3 (10.71)18.2507
2000's2 (7.14)29.6817
2010's3 (10.71)24.3611
2020's4 (14.29)2.80

Authors

AuthorsStudies
Chen, L; Gao, Y; Hong, Y; Hu, C; Huang, Z; Liu, D; Ren, B; Tian, X; Wang, X; Yin, R; Yu, Y; Zhang, C; Zhang, Z; Zhou, J; Zhu, C1
Anane, S; Attou, R; Barreto Gutierrez, L; Cismas, BV; De Bels, D; Gallerani, A; Honore, PM; Kaefer, K; Preseau, T; Redant, S1
Jiang, W; Liu, Y; Ouyang, Z; Qiu, Y; Shen, J; Wan, F; Zeng, Y; Zhong, J1
Chen, MZ; Deng, X; Dong, X; Guo, SB; Li, AJ; Lin, JH; Lin, ZF; Lin, ZH; Liu, JX; Mei, X; Shi, B; Tian, YP; Yuan, DS; Yuan, SY; Zha, JJ; Zhang, F; Zhang, L; Zhou, P1
Su, H; Wang, H1
Cai, GJ; Chen, AF; Kong, Y; Le, YY; Liu, C; Liu, X; Shen, FM; Su, DF1
Lei, H; Li, Q; Liu, A; Liu, X; Su, D; Yang, Y1
Liu, C; Liu, JG; Liu, Q; Su, DF; Sun, L; Zhang, GF; Zhang, X1
Gong, P; Jiang, H; Liu, H; Zhang, Y; Zhao, GK1
Chen, XY; Xi, PX; Yan, YZ2
Chen, HC; Chen, L; Su, MC; Xu, SH1
Chen, HH1
Su, JY; Tang, C; Wu, L1
Chen, HC; Wang, ZG; Xiao, DM1
Dai, ZY; Sun, XY; Tong, HH; Xiao, YF; Xu, ZY; Yao, T; Yuan, M1
Sun, RY1
Coppo, PA; Hammerschmidt, DE; Jacob, HS; Xiu, RJ1
Grantham, KD; Kelly, DR; Li, JX; Oliver, JR; Philips, JB1
Cui, YH; Liu, YQ; Lun, N; Wang, BS; Wang, LZ; Zhu, FH1
Xu, S1
Shen, WT1
Xiao, YF; Yao, T1
Chen, HC; Wang, XL; Xiao, DM2
Chen, HC; Tao, YP; Xiao, DM1
Chen, HC; Wu, QX; Xu, SH1
Chen, HC; Xiao, DM1

Trials

3 trial(s) available for anisodamine and Shock, Septic

ArticleYear
Effectiveness of anisodamine for the treatment of critically ill patients with septic shock: a multicentre randomized controlled trial.
    Critical care (London, England), 2021, 09-27, Volume: 25, Issue:1

    Topics: Critical Illness; Humans; Shock, Septic; Solanaceous Alkaloids; Treatment Outcome

2021
Anisodamine hydrobromide in the treatment of critically ill patients with septic shock: a multicenter randomized controlled trial.
    Annals of medicine, 2023, Volume: 55, Issue:2

    Topics: Critical Illness; Humans; Prospective Studies; Sepsis; Shock, Septic

2023
[Effects of penehyclidine hydrochloride on the splanchnic perfusion of patients with septic shock].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2008, Volume: 20, Issue:3

    Topics: Adult; Aged; Female; Humans; Male; Microcirculation; Middle Aged; Perfusion; Quinuclidines; Resuscitation; Shock, Septic; Solanaceous Alkaloids; Viscera

2008

Other Studies

25 other study(ies) available for anisodamine and Shock, Septic

ArticleYear
Anisodamine microcirulatory effects in septic shock: be aware of cardiac side effects.
    Critical care (London, England), 2021, 12-16, Volume: 25, Issue:1

    Topics: Drug-Related Side Effects and Adverse Reactions; Heart; Humans; Shock, Septic; Solanaceous Alkaloids

2021
Anisodamine hydrobromide attenuates oxidative stress and proinflammatory cytokines in septic rats induced by cecal ligation and puncture.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Dec-31, Volume: 68, Issue:12

    Topics: Animals; Atropine Derivatives; Cytokines; Disease Models, Animal; Interleukin-6; Ligation; Oxidative Stress; Punctures; Rats; Sepsis; Shock, Septic; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2022
[Reunderstanding and prospect of treatment of septic shock with anisodamine].
    Zhonghua wei zhong bing ji jiu yi xue, 2015, Volume: 27, Issue:1

    Topics: Drugs, Chinese Herbal; Humans; Shock, Septic; Solanaceous Alkaloids; Vasodilator Agents

2015
Antishock effect of anisodamine involves a novel pathway for activating alpha7 nicotinic acetylcholine receptor.
    Critical care medicine, 2009, Volume: 37, Issue:2

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Base Sequence; Cell Line; China; DNA Primers; Interleukin-1beta; Macrophages, Peritoneal; Mice; Nicotinic Agonists; Nicotinic Antagonists; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Shock, Septic; Solanaceous Alkaloids; Tumor Necrosis Factor-alpha; Vagotomy

2009
The antishock effect of anisodamine requires the upregulation of α7 nicotine acetylcholine receptors by IL-10.
    Life sciences, 2011, Sep-12, Volume: 89, Issue:11-12

    Topics: Adrenergic alpha-Agonists; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cells, Cultured; China; Cytokines; Dose-Response Relationship, Drug; Interleukin-10; Interleukin-1beta; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Nicotinic; Shock, Septic; Solanaceous Alkaloids; Spleen; Survival Rate; Tumor Necrosis Factor-alpha; Up-Regulation

2011
Combined administration of anisodamine and neostigmine produces anti-shock effects: involvement of α7 nicotinic acetylcholine receptors.
    Acta pharmacologica Sinica, 2012, Volume: 33, Issue:6

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholinesterase Inhibitors; Dogs; Drug Therapy, Combination; Gene Knockout Techniques; Hemodynamics; Interleukin-1beta; Lipopolysaccharides; Liver; Mice; Mice, Knockout; Neostigmine; Receptors, Nicotinic; Shock, Hemorrhagic; Shock, Septic; Solanaceous Alkaloids; Survival Rate; Tumor Necrosis Factor-alpha; Vasodilator Agents

2012
[Studies on the anti-shock mechanism of anisodamine. II. Dynamic change in blood histamine during endotoxic shock and effect of anisodamine on hypotensive effect of histamine].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1983, Volume: 5, Issue:6

    Topics: Animals; Blood Pressure; Histamine; Rabbits; Shock, Septic; Solanaceous Alkaloids; Vasodilator Agents

1983
[Effect of 5-HT and anisodamine in endotoxic shock].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1984, Volume: 6, Issue:2

    Topics: Animals; Blood Platelets; Dogs; Platelet Count; Serotonin; Shock, Septic; Solanaceous Alkaloids

1984
Large dose atropine alkaloids in the treatment of shock.
    Resuscitation, 1983, Volume: 10, Issue:3

    Topics: Adult; Atropine; Child; China; Humans; Injections, Intravenous; Scopolamine; Scopolamine Derivatives; Shock, Septic; Solanaceous Alkaloids

1983
Experimental study in rabbits of the antishock effect of anisodamine (654-2), and its mechanism of action.
    Resuscitation, 1983, Volume: 10, Issue:3

    Topics: Animals; Blood Pressure; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Peritonitis; Rabbits; Shock, Hemorrhagic; Shock, Septic; Solanaceous Alkaloids; Vasoconstrictor Agents

1983
[Changes in the plasma levels of cyclic AMP and cyclic GMP in dogs with endotoxin shock and effects of anisodamine on these changes].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1983, Volume: 5, Issue:3

    Topics: Animals; Cyclic AMP; Cyclic GMP; Dogs; Escherichia coli; Parasympatholytics; Shock, Septic; Solanaceous Alkaloids

1983
Effects of anisodamine on cardiovascular activities in endotoxin-shocked dogs.
    Chinese medical journal, 1984, Volume: 97, Issue:12

    Topics: Animals; Blood Pressure; Cardiovascular System; Dogs; Female; Male; Myocardial Contraction; Shock, Septic; Solanaceous Alkaloids; Vascular Resistance; Vasodilator Agents

1984
[Effects of anisodamine on pulmonary circulation and function of the dog in shock].
    Zhonghua yi xue za zhi, 1982, Volume: 62, Issue:8

    Topics: Animals; Dogs; Lung; Oxygen; Parasympatholytics; Pulmonary Circulation; Shock, Septic; Solanaceous Alkaloids

1982
Anisodamine inhibits thromboxane synthesis, granulocyte aggregation, and platelet aggregation. A possible mechanism for its efficacy in bacteremic shock.
    JAMA, 1982, Mar-12, Volume: 247, Issue:10

    Topics: Animals; Cell Aggregation; Cricetinae; Depression, Chemical; Granulocytes; Humans; Ibuprofen; Platelet Aggregation; Scopolamine Derivatives; Shock, Septic; Solanaceous Alkaloids; Structure-Activity Relationship; Thromboxane B2; Thromboxanes; Vasodilator Agents

1982
Effects of cholinergic blockade on hemodynamic disturbances and intestinal lesions in endotoxic shock in newborn piglets.
    Shock (Augusta, Ga.), 1994, Volume: 2, Issue:2

    Topics: Analysis of Variance; Animals; Animals, Newborn; Blood Pressure; Carbon Dioxide; Cardiac Output; Diarrhea; Digestive System; Dose-Response Relationship, Drug; Endotoxins; Female; Heart Rate; Hemodynamics; Oxygen; Parasympatholytics; Partial Pressure; Pulmonary Artery; Shock, Septic; Solanaceous Alkaloids; Stroke Volume; Swine; Thromboxane B2; Time Factors; Tumor Necrosis Factor-alpha; Vascular Resistance; Vomiting

1994
Effects of dexamethasone, cyproheptadine, anisodamine, and dinoprostone on TNF alpha production in endotoxic shock.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyproheptadine; Dexamethasone; Dinoprostone; Glucocorticoids; Liver; Male; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Shock, Septic; Solanaceous Alkaloids; Tumor Necrosis Factor-alpha

1999
[A preliminary study of the inhibiting mechanism of anisodamine on rabbit platelets activated by E. coli endotoxin].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1990, Volume: 12, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cyclic AMP; Endotoxins; Escherichia coli; Female; Male; Membrane Fluidity; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Shock, Septic; Solanaceous Alkaloids

1990
[Effect of anisodamine on serum beta-glucuronidase activity in shock].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1985, Volume: 5, Issue:9

    Topics: Animals; Dogs; Drug Synergism; Female; Glucuronidase; Male; Shock, Septic; Solanaceous Alkaloids; Vasodilator Agents

1985
[Cardiovascular effects of anisodamine during endotoxin shock in anaesthetized dogs].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1986, Volume: 6, Issue:11

    Topics: Animals; Dogs; Female; Heart; Hemodynamics; Male; Shock, Septic; Solanaceous Alkaloids

1986
[Experimental studies on the effect of anisodamine (654-2) on endotoxic shock].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1987, Volume: 9, Issue:4

    Topics: Animals; Glucuronidase; Male; Mice; Neutrophils; Rabbits; Rats; Rats, Inbred Strains; Shock, Septic; Solanaceous Alkaloids

1987
Inhibitory effects of anisodamine on endotoxin-induced prostaglandin production by cells in culture.
    Chinese medical journal, 1988, Volume: 101, Issue:12

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cells, Cultured; Dinoprost; Female; Macrophages; Mice; Peritoneal Cavity; Shock, Septic; Solanaceous Alkaloids; Thromboxane B2

1988
[Changes in the plasma 6-keto-PGF1 alpha level during canine endotoxic shock].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1985, Volume: 7, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Dogs; Female; Male; Parasympatholytics; Platelet Aggregation; Shock, Septic; Solanaceous Alkaloids

1985
Effects of anisodamine on plasma levels of thromboxane B2 (TXB2) and 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha) in rat with septic shock.
    Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, 1988, Volume: 3, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Drugs, Chinese Herbal; Infusions, Intravenous; Male; Rats; Rats, Inbred Strains; Shock, Septic; Solanaceous Alkaloids; Thromboxane B2

1988
Anisodamine effects on functional and morphologic changes of platelets in endotoxinemic rabbits.
    Chinese medical journal, 1985, Volume: 98, Issue:2

    Topics: Animals; Blood Platelets; Female; Male; Platelet Aggregation; Rabbits; Shock, Septic; Solanaceous Alkaloids; Vasodilator Agents

1985
Changes in the plasma levels of PGE, PGF2 alpha and 6-keto-PGF1 alpha in canine endotoxic shock.
    Chinese medical journal, 1985, Volume: 98, Issue:7

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Animals; Child; Child, Preschool; Dinoprost; Dogs; Epoprostenol; Female; Humans; Infant; Male; Prostaglandins E; Prostaglandins F; Shock, Septic; Solanaceous Alkaloids; Vasodilator Agents

1985