Page last updated: 2024-10-22

aniracetam and Amnesia

aniracetam has been researched along with Amnesia in 7 studies

Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)

Research Excerpts

ExcerptRelevanceReference
"The effects of N-(2,6-dimethyl-phenyl)-2-(2-oxo-1-pyrrolidinyl)-acetamide [DM-9384], a cyclic derivative of GABA, were investigated in the cycloheximide (CXM)-induced amnesia animal model using the passive avoidance task."7.68Effects of DM-9384, a cyclic derivative of GABA, on amnesia and decreases in GABAA and muscarinic receptors induced by cycloheximide. ( Hatanaka, S; Ishihara, S; Kameyama, T; Kojima, H; Murase, K; Nabeshima, T; Sakurai, T; Takasu, Y; Tohyama, K; Yamasaki, T, 1991)
"The effects of N-(2,6-dimethyl-phenyl)-2-(2-oxo-1-pyrrolidinyl) acetamide (DM-9384), a new pyrrolidone derivative, were investigated on ethanol- and chlordiazepoxide (CDP)-induced amnesia animal model using the passive avoidance task in comparison with aniracetam, another pyrrolidone derivative."7.68Effects of DM-9384, a pyrrolidone derivative, on alcohol- and chlordiazepoxide-induced amnesia in mice. ( Kameyama, T; Nabeshima, T; Tohyama, K, 1990)
"The pyrrolidinone derivative aniracetam given orally immediately after acquisition of an inhibitory avoidance response reproducibly ameliorated scopolamine-induced amnesia in female rats in an extensive series of test sessions conducted over a 1-year period."3.69Aniracetam reverses memory impairment in rats. ( Jenck, F; Martin, JR; Moreau, JL, 1995)
"The effects of N-(2,6-dimethyl-phenyl)-2-(2-oxo-1-pyrrolidinyl)-acetamide [DM-9384], a cyclic derivative of GABA, were investigated in the cycloheximide (CXM)-induced amnesia animal model using the passive avoidance task."3.68Effects of DM-9384, a cyclic derivative of GABA, on amnesia and decreases in GABAA and muscarinic receptors induced by cycloheximide. ( Hatanaka, S; Ishihara, S; Kameyama, T; Kojima, H; Murase, K; Nabeshima, T; Sakurai, T; Takasu, Y; Tohyama, K; Yamasaki, T, 1991)
"The effects of N-(2,6-dimethyl-phenyl)-2-(2-oxo-1-pyrrolidinyl) acetamide (DM-9384), a new pyrrolidone derivative, were investigated on ethanol- and chlordiazepoxide (CDP)-induced amnesia animal model using the passive avoidance task in comparison with aniracetam, another pyrrolidone derivative."3.68Effects of DM-9384, a pyrrolidone derivative, on alcohol- and chlordiazepoxide-induced amnesia in mice. ( Kameyama, T; Nabeshima, T; Tohyama, K, 1990)
"The effects of N-(2,6-dimethyl-phenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (DM-9384), a cyclic derivative of GABA, were investigated and compared with those of aniracetam in an animal model of amnesia, using a passive avoidance task with animals that have GABAergic neuronal dysfunctions."3.68Effects of DM-9384 in a model of amnesia based on animals with GABAergic neuronal dysfunctions. ( Itoh, J; Kameyama, T; Nabeshima, T; Noda, Y; Tohyama, K, 1990)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Angelucci, L1
Calvisi, P1
Catini, R1
Cosentino, U1
Cozzolino, R1
De Witt, P1
Ghirardi, O1
Giannessi, F1
Giuliani, A1
Guaraldi, D1
Martin, JR1
Moreau, JL1
Jenck, F1
Nabeshima, T4
Tohyama, K3
Murase, K1
Ishihara, S1
Kameyama, T4
Yamasaki, T1
Hatanaka, S1
Kojima, H1
Sakurai, T1
Takasu, Y1
Tanabe, S1
Ikeda, Y1
Sugawa, M1
Iwasaki, T1
Noda, Y1
Itoh, J2

Other Studies

7 other studies available for aniracetam and Amnesia

ArticleYear
Synthesis and amnesia-reversal activity of a series of 7- and 5-membered 3-acylamino lactams.
    Journal of medicinal chemistry, 1993, May-28, Volume: 36, Issue:11

    Topics: Amnesia; Animals; Brain; Cholinesterase Inhibitors; Drug Design; Electroshock; In Vitro Techniques;

1993
Aniracetam reverses memory impairment in rats.
    Pharmacological research, 1995, Volume: 31, Issue:2

    Topics: Administration, Oral; Amnesia; Animals; Avoidance Learning; Disease Models, Animal; Dose-Response Re

1995
Effects of DM-9384, a cyclic derivative of GABA, on amnesia and decreases in GABAA and muscarinic receptors induced by cycloheximide.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1

    Topics: Amnesia; Animals; Avoidance Learning; Central Nervous System Agents; Cycloheximide; Male; Mice; Prot

1991
Effects of DM-9384, a pyrrolidone derivative, on alcohol- and chlordiazepoxide-induced amnesia in mice.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:2

    Topics: Amnesia; Animals; Avoidance Learning; Bicuculline; Central Nervous System Agents; Chlordiazepoxide;

1990
[Effects of BY-1949 on three kinds of experimental amnesia in rodents].
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1990, Volume: 10, Issue:2

    Topics: Amnesia; Animals; Avoidance Learning; Dibenzoxazepines; Disease Models, Animal; Male; Mice; Pyrrolid

1990
Effects of DM-9384 in a model of amnesia based on animals with GABAergic neuronal dysfunctions.
    European journal of pharmacology, 1990, Mar-20, Volume: 178, Issue:2

    Topics: Amnesia; Animals; Avoidance Learning; Bicuculline; Central Nervous System Agents; gamma-Aminobutyric

1990
Utility of an elevated plus-maze for the evaluation of memory in mice: effects of nootropics, scopolamine and electroconvulsive shock.
    Psychopharmacology, 1990, Volume: 101, Issue:1

    Topics: Amnesia; Animals; Electroshock; Injections, Intraventricular; Male; Memory; Mice; Mice, Inbred Strai

1990