angiotensinogen has been researched along with Substance-Related-Disorders* in 2 studies
2 other study(ies) available for angiotensinogen and Substance-Related-Disorders
Article | Year |
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The association study of DRD2, ACE and AGT gene polymorphisms and metamphetamine dependence.
We investigated the association between metamphetamine dependence and TaqI A polymorphism of the dopamine receptor D2 gene (DRD2), I/D polymorphism in angiotensin-converting enzyme (ACE) and M235T polymorphism of the angiotensinogen gene (AGT) in 93 unrelated metamphetamine-dependent subjects and 131 controls. Our results did not prove any association of TaqI A polymorphism of the DRD2 gene, I/D polymorphism of ACE gene, and M235T polymorphism of AGT gene with the metamphetamine dependence in Caucasians of Czech origin. However, a significant difference in allele I frequency between male and female control groups for the I/D ACE polymorphism (p<0.03) was found. Topics: Adult; Alleles; Angiotensinogen; Deoxyribonucleases, Type II Site-Specific; Female; Gene Frequency; Genotype; Humans; Male; Methamphetamine; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Receptors, Dopamine D2; Sex Characteristics; Substance-Related Disorders | 2001 |
Laxative-induced hypokalemia, sodium depletion and hyperreninemia. Effects of potassium and sodium replacement on the renin-angiotensin-aldosterone system.
A patients with marked chronic hypokalemia (potassium, 1.7 to 2;3 meg/litre) and sodium depletion secondary to lazative abuse and dietary inadequacy was studied with respect to the renin-aldosterone system during sequential potassium and potassium-plus-sodium replacement. Extreme hyperreninemia of 20 Goldblatt units X 10-minus 4 was reduced to 0.9 with potassium replacement alone. Aldosteron excretion (15.8 mug/24 h) was initially low for a sodium-deprived state and high for a potassium-deprived state; it increased with potassium administration, but this rise was opposed by decreases in renin secretion induced by potassium and sodium administration. The results provide clinical confirmation of a dual effect of potassium on aldosterone secretion, with renin as a mediator. Topics: Aldosterone; Angiotensin II; Angiotensinogen; Cathartics; Dose-Response Relationship, Drug; Female; Humans; Hypokalemia; Middle Aged; Potassium; Radioimmunoassay; Renin; Sodium; Substance-Related Disorders; Water-Electrolyte Balance | 1975 |