Page last updated: 2024-08-22

angiotensin ii and Renal Insufficiency, Chronic

angiotensin ii has been researched along with Renal Insufficiency, Chronic in 73 studies

Research

Studies (73)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (2.74)	29.6817
2010's	54 (73.97)	24.3611
2020's	17 (23.29)	2.80

Authors

Authors	Studies
Alenina, N; Bader, M; Clahsen-van Groningen, MC; Danser, AHJ; Essers, J; Garrelds, IM; Qadri, F; Ridwan, Y; Roks, AJM; van der Linden, J; van der Pluijm, I; van Thiel, BS; Vermeij, M	1
Bethea, JR; Drummer, C; Hu, W; Jiang, X; Kunapuli, SP; Lu, Y; Saaoud, F; Shao, Y; Sun, J; Sun, Y; Vazquez-Padron, RI; Wang, H; Wu, S; Xu, K; Yang, X; Yu, J	1
Berghaus, RD; Brown, SA; Coleman, AE; Lourenço, BN; Schmiedt, CW; Tarigo, JL	1
Pao, AC; Raphael, KL; Ravikumar, NPG	1
Chen, Z; Ding, G; Feng, J; Hu, J; Liang, W; Luo, Q; Luo, Z; Yang, H; Zhang, Z; Zhu, Z	1
Fogo, AB; Ma, LJ; Matsushita, K; Wang, J; Yang, HC; Zhong, J	1
Chen, Z; Ding, G; Feng, J; Hao, Y; Hu, J; Huang, X; Liang, W; Luo, Z; Yang, X; Zhang, Z; Zhu, Z	1
Alirezaei, A; Argani, H; Ghorbanihaghjo, A; Jabarpour, M; Panah, F; Ranjbarzadhag, M; Rashtchizadeh, N; Sanajou, D	1
Beer Stolz, D; Cerqueira, DM; Fu, H; Ho, J; Li, Y; Liu, Y; Rush, BM; Tan, RJ; Zhou, D	1
Bushinsky, DA; Buysse, JM; Wesson, DE	1
Chen, P; Cheng, Q; Huo, C; Li, J; Liu, J; Lu, L; Miao, N; Ni, J; Xie, H; Xu, D; Yin, F; Yu, C; Zhang, W; Zhang, Y; Zheng, P; Zhou, L; Zhou, Z	1
Antlanger, M; Berlakovich, G; Böhmig, GA; Domenig, O; Eskandary, F; Fajkovic, H; Grobe, N; Gruber, C; Hellinger, R; Kain, R; Kaltenecker, CC; Kopecky, C; Kovarik, JJ; Poglitsch, M; Rahman, M; Säemann, MD; Stegbauer, J	1
Gan, H; He, J; Li, C; Xia, W; Xia, Y; Zhao, H; Zhong, X	1
Chen, Z; Ding, G; Feng, J; Hu, J; Liang, W; Wang, H; Yang, D; Yang, Q; Yang, Y; Zhu, Z	1
Lu, K; Shi, C; Xia, H; Zhang, B; Zhang, P	1
Benetti, A; Girardi, ACC; Luchi, WM; Martins, FL; Seguro, AC; Sene, LB; Shimizu, MHM	1
Fujita, Y; Hoshino, S; Ichikawa, D; Inoue, K; Kamijo-Ikemori, A; Kimura, K; Ohata, K; Shibagaki, Y; Sugaya, T; Tanabe, J; Togo, T; Watanabe, M	1
Bovée, DM; Clahsen-van Groningen, MC; Danser, AHJ; Domenig, O; Foster, D; Garrelds, IM; Hoorn, EJ; Huang, S; Kim, JB; Lu, X; Melton, L; Poglitsch, M; Ren, L; Uijl, E; van Veghel, R; Zlatev, I	1
Hoang, T; Revoori, R; Rianto, F; Sparks, MA	1
Qian, J; Sun, B; Wang, H; Xing, C; Zhao, X	1
Gan, X; Lu, L; Miao, N; Shen, Y; Wang, B; Xu, D; Xu, J; Xue, H; Yang, L; Zhang, W; Zhou, L	1
Beanlands, RS; Burns, KD; Croteau, E; DaSilva, JN; deKemp, RA; Hadizad, T; Ismail, B	1
Armeni, A; Cerantonio, A; Fuiano, G; Simeoni, M; Summaria, C	1
Ding, G; Ma, Y; Yang, J; Yang, Q; Yang, Y	1
Pruszynski, J; Roehm, B; Simoni, J; Wesson, DE	1
Cechova, S; Chan, F; Dong, F; Kelley, MJ; Le, TH; Ruiz, P	1
Kraut, JA; Madias, NE	1
Andrew, R; Freel, EM; Homer, NZM; Jardine, AG; Mark, PB; McQuarrie, EP; Rankin, AJ; Taylor, AHM	1
Beddhu, S; Huang, Y; Tang, L; Tian, M; Wu, Y	1
Hitomi, H; Kitabayashi, C; Kobara, H; Kobori, H; Konishi, Y; Li, L; Masaki, T; Morikawa, T; Nakano, D; Nishiyama, A; Zhang, Y	1
Chen, L; Feng, Y; Gan, H; Haydon, RC; He, TC; Huang, B; Huang, S; Lei, J; Liu, W; Luo, W; Luu, HH; Shu, Y; Wang, X; Xia, Y; Yan, S; Yu, X; Yuan, C; Zeng, L; Zeng, Z; Zhang, B; Zhang, H; Zhang, L; Zhang, R; Zhang, X; Zhao, C	1
Cai, H; Chen, S	1
Ban, TH; Chang, YS; Choi, BS; Jang, IA; Kim, EN; Kim, MY; Lim, JH; Park, CW; Yoon, HE	1
Chen, B	1
Ichikawa, H; Kimura, Y; Narita, I; Narita, M; Okumura, K; Osanai, T; Shimada, M; Tanaka, M; Tomita, H	1
Arruda-Junior, DF; Benetti, A; Beraldo, JI; Borges-Júnior, FA; Dariolli, R; Girardi, ACC; Jensen, L; Luchi, WM; Martins, FL; Seguro, AC; Shimizu, MH	1
Fang, F; Kim, C; Liu, GC; Scholey, JW; Yassa, R; Zhou, J	1
Akakabe, Y; Ikeda, K; Irie, D; Kato, T; Kawahito, H; Kishida, S; Matoba, S; Matsubara, H; Mori, Y; Ogata, T; Takata, H; Ueyama, T; Wakana, N; Yamada, H	1
Ding, W; Gu, Y; Xu, C; Zhang, M	1
Ding, XQ; Lv, WL; Teng, J; Zhang, XY; Zhong, YH	1
Čertíková Chábová, V; Červenka, L; Hammock, BD; Husková, Z; Hwang, SH; Imig, JD; Kitada, K; Kompanowska-Jezierska, E; Kramer, HJ; Kujal, P; Nishiyama, A; Sadowski, J; Škaroupková, P; Vernerová, Z; Walkowska, A	1
Xu, B; Xu, C; Xu, Z	1
Manucha, W	1
Crowley, SD; Griffiths, R; Jin, H; Karlovich, NS; Lin, EE; Mao, A; Patel, MB; Song, YS; Sparks, MA; Wu, M; Zhang, J	1
Chen, X; Dickhout, JG; Gao, B; Krepinsky, JC; Li, R; Lu, C; Mohammed-Ali, Z; Wang, TN; Yum, V	1
Re, RN	2
Farnham, MM; Hildreth, CM; Phillips, JK; Pilowsky, PM; Saha, M; Sun, QJ; Yao, Y	1
Asare, Y; Bruck, H; Heinze, G; Jankowski, J; Jankowski, V; Liehn, E; Machado, FB; Marx, N; Muñoz-Castañeda, JR; Pineda-Martos, C; Raya-Bermudez, A; Rodriguez, M; Salem, S; Staudt, M; Welker, P; Zidek, W	1
Ikeda, H; Kitazono, T; Noguchi, H; Suehiro, T; Tokumoto, M; Toyonaga, J; Tsuruya, K; Yamada, S	1
Eltzschig, HK; Grenz, A; Jin, J; Kellems, RE; Luo, R; Tao, L; Wu, H; Xia, Y; Zhang, W; Zhang, Y; Zhao, C	1
Ask, K; Carlisle, RE; Cruz, GL; Dickhout, JG; Lu, C; Mohammed-Ali, Z; Werner, KE	1
Azegami, T; Hayashi, K; Itoh, H; Nakamura, M; Oguchi, H; Sakamaki, Y; Sasamura, H; Tokuyama, H; Wakino, S	1
Basile, DP; Collett, JA; Ivancic, CM; Mehrotra, P; Patel, JB	1
Alvarez-Prats, A; Baranova, IN; Bocharov, AV; Eggerman, TL; Hu, X; Huang, YG; Mullick, AE; Patterson, AP; Remaley, AT; Souza, AC; Star, RA; Street, JM; Vishnyakova, TG; Wilkins, KJ; Yuen, PS	1
Diedrich, A; Finney, C; Harris, RC; Kloepfer, LA; Zeng, F	1
Ask, K; Carlisle, RE; Dickhout, JG; Krepinsky, JC; Lu, C; Lukic, D; Marway, MK; Mohammed-Ali, Z	1
Chen, C; Han, Q; Liang, W; Luo, Z; Lv, X; Su, K; Wang, Y; Yan, M; Zeng, P	1
Delafontaine, P; Du, J; Garcia, G; Han, G; Hu, Z; Mitch, WE; Zhang, L	1
Macconi, D	1
Edwards, NC; Ferro, CJ; Hammer, F; Hughes, BA; Steeds, RP; Stewart, PM; Townend, JN	1
Ahn, SY; Ahn, YM; Chung, JH; Kang, SW; Kim, SD; Kim, SK; Lee, BC; Lee, SH	1
Kagami, S; Kondo, S; Urushihara, M	1
Blackburn, MR; Dai, Y; Kellems, RE; Ning, C; Sun, H; Tao, L; Wang, W; Xia, Y; Yu, H; Zhang, W; Zhang, Y	1
Nishiyama, A	1
Amaram, JS; Hillerson, D; Raizada, V; Skipper, B	1
Baucke, J; Danser, AH; Divac, N; Fraune, C; Frenay, AR; Garrelds, IM; Hölzel, A; Jankowski, V; Krebs, C; Lange, S; Nguyen, G; Schwedhelm, E; Stahl, R; Streichert, T; van Goor, H; Velden, J; Wenzel, UO	1
Dejima, T; Maeda, A; Mitsuhashi, H; Tamura, K; Tokita, Y; Tsurumi-Ikeya, Y; Umemura, S; Uneda, K; Wakui, H; Yamaguchi, S	1
Mitani, S; Taniguchi, K; Yabuki, A; Yamato, O	1
Avinash Raj, T; Kalai Gana Selvi, S; Kaliappan, G; Mahesh Kumar, J; Moorthy, R; Nagarajan, P	1
Bidani, AK; Griffin, KA; Loutzenhiser, R; Polichnowski, AJ	1
de Borst, MH; Mirković, K	1
Fujigaki, Y; Fukasawa, H; Hishida, A; Kato, A; Nakagawa, T; Nakamura, Y; Ohashi, N; Suzuki, F; Suzuki, H; Yamamoto, T	1

Reviews

13 review(s) available for angiotensin ii and Renal Insufficiency, Chronic

Article	Year
Acid-Mediated Kidney Injury Across the Spectrum of Metabolic Acidosis. Advances in chronic kidney disease, 2022, Volume: 29, Issue:4 Topics: Acidosis; Aldosterone; Ammonium Compounds; Angiotensin II; Citrates; Endothelin-1; Humans; Kidney; Renal Insufficiency, Chronic	2022
The impact of dyslipidemia and oxidative stress on vasoactive mediators in patients with renal dysfunction. International urology and nephrology, 2019, Volume: 51, Issue:12 Topics: Angiotensin II; Dyslipidemias; Endothelin-1; Humans; Nitric Oxide; Oxidative Stress; Proprotein Convertase 9; Renal Insufficiency, Chronic	2019
Angiotensin receptors in the kidney and vasculature in hypertension and kidney disease. Molecular and cellular endocrinology, 2021, 06-01, Volume: 529 Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Gene Expression Regulation; Humans; Hypertension; Kidney Tubules, Proximal; Mice; Mice, Knockout; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Insufficiency, Chronic; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance	2021
Current evidence on the use of anti-RAAS agents in congenital or acquired solitary kidney. Renal failure, 2017, Volume: 39, Issue:1 Topics: Adult; Age Factors; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Child; Disease Progression; Female; Humans; Hypertension; Kidney; Male; Protective Agents; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Renin-Angiotensin System; Sex Factors; Solitary Kidney	2017
Retarding progression of chronic kidney disease: use of modalities that counter acid retention. Current opinion in nephrology and hypertension, 2018, Volume: 27, Issue:2 Topics: Acid-Base Imbalance; Aldosterone; Angiotensin II; Animals; Buffers; Citrates; Dietary Proteins; Disease Progression; Endothelins; Fibrosis; Fruit; Humans; Kidney; Renal Insufficiency, Chronic; Sodium Bicarbonate; Sodium Citrate; Vegetables	2018
[Mitochondria and oxidative stress participation in renal inflammatory process]. Medicina, 2014, Volume: 74, Issue:3 Topics: Angiotensin II; Animals; Apoptosis; Cytoprotection; Ergocalciferols; Humans; Kidney Cortex; Kidney Tubules; Mitochondria; Nephritis; NF-kappa B; Oxidative Stress; Renal Insufficiency, Chronic; Vitamins	2014
A possible mechanism for the progression of chronic renal disease and congestive heart failure. Journal of the American Society of Hypertension : JASH, 2015, Volume: 9, Issue:1 Topics: Angiotensin II; Disease Progression; Heart Failure; Humans; Neurodegenerative Diseases; Renal Insufficiency, Chronic; Renin-Angiotensin System; Up-Regulation	2015
An Expanded View of Progressive Cardiorenal Disorders. The American journal of the medical sciences, 2016, Volume: 351, Issue:6 Topics: Angiotensin II; Angiotensinogen; Cardio-Renal Syndrome; Disease Progression; Heart Failure; Humans; Parathyroid Hormone-Related Protein; Peptidyl-Dipeptidase A; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Signal Transduction; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A	2016
Targeting the renin angiotensin system for remission/regression of chronic kidney disease. Histology and histopathology, 2010, Volume: 25, Issue:5 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetic Nephropathies; Drug Therapy, Combination; Glomerulosclerosis, Focal Segmental; Humans; Hypertension, Renal; Models, Biological; Proteinuria; Remission Induction; Renal Insufficiency, Chronic; Renin-Angiotensin System	2010
[Progress of pediatric nephrology]. Nihon Jinzo Gakkai shi, 2011, Volume: 53, Issue:1 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antibodies, Monoclonal, Murine-Derived; Biomarkers; Child; Clinical Trials as Topic; Early Diagnosis; Humans; Immunologic Factors; Kidney; Losartan; Mutation; Myosin Heavy Chains; Nephrotic Syndrome; Nerve Tissue Proteins; Renal Insufficiency, Chronic; Rituximab; Urinary Tract	2011
[Mechanisms responsible for the renoprotective effects of renin-angiotensin inhibitors]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2012, Volume: 132, Issue:4 Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Humans; Hypertension; Kidney; Mineralocorticoid Receptor Antagonists; Rats; Receptors, Mineralocorticoid; Renal Insufficiency, Chronic; Renin-Angiotensin System	2012
Angiotensin II-mediated left ventricular abnormalities in chronic kidney disease. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2012, Volume: 60, Issue:5 Topics: Aldosterone; Angiotensin II; Animals; Heart Ventricles; Humans; Renal Insufficiency, Chronic; Ventricular Dysfunction, Left	2012
Renal microvascular dysfunction, hypertension and CKD progression. Current opinion in nephrology and hypertension, 2013, Volume: 22, Issue:1 Topics: Angiotensin II; Blood Pressure; Disease Progression; Homeostasis; Humans; Hypertension, Renal; Kidney Glomerulus; Microvessels; Nitric Oxide; Renal Insufficiency, Chronic	2013

Trials

4 trial(s) available for angiotensin ii and Renal Insufficiency, Chronic

Article	Year
Cigarette Smoking Attenuates Kidney Protection by Angiotensin-Converting Enzyme Inhibition in Nondiabetic Chronic Kidney Disease. American journal of nephrology, 2017, Volume: 46, Issue:4 Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cigarette Smoking; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Oxidative Stress; Prospective Studies; Proteinuria; Renal Insufficiency, Chronic; Smoking Cessation	2017
Non-uniform relationship between salt status and aldosterone activity in patients with chronic kidney disease. Clinical science (London, England : 1979), 2018, 01-31, Volume: 132, Issue:2 Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Cross-Over Studies; Diet, Sodium-Restricted; Humans; Hypertension; Middle Aged; Renal Insufficiency, Chronic; Renin-Angiotensin System; Sodium Chloride, Dietary; Vasoconstrictor Agents; Young Adult	2018
The effect of spironolactone upon corticosteroid hormone metabolism in patients with early stage chronic kidney disease. Clinical endocrinology, 2010, Volume: 73, Issue:5 Topics: Adrenal Cortex Hormones; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hydrocortisone; Kidney Failure, Chronic; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Renal Insufficiency, Chronic; Renin; Spironolactone; Tetrahydrocortisol	2010
Urinary angiotensinogen as a marker of intrarenal angiotensin II activity associated with deterioration of renal function in patients with chronic kidney disease. Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensinogen; Antihypertensive Agents; Biomarkers; Collagen Type I; Female; Humans; Kidney; Losartan; Male; Middle Aged; Renal Insufficiency, Chronic	2007

Other Studies

56 other study(ies) available for angiotensin ii and Renal Insufficiency, Chronic

Article	Year
In Vivo Renin Activity Imaging in the Kidney of Progeroid International journal of molecular sciences, 2021, Nov-18, Volume: 22, Issue:22 Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; DNA Damage; DNA Repair; DNA-Binding Proteins; Endonucleases; Female; Gene Expression Regulation; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Humans; Kidney; Losartan; Male; Mice; Mice, Knockout; Progeria; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Signal Transduction	2021
Aorta in Pathologies May Function as an Immune Organ by Upregulating Secretomes for Immune and Vascular Cell Activation, Differentiation and Trans-Differentiation-Early Secretomes may Serve as Drivers for Trained Immunity. Frontiers in immunology, 2022, Volume: 13 Topics: Angiotensin II; Aorta; Caspase 1; Cell Differentiation; Cell Transdifferentiation; COVID-19; Cytokines; Endothelial Cells; Humans; Middle East Respiratory Syndrome Coronavirus; NF-E2-Related Factor 2; Renal Insufficiency, Chronic; Secretome	2022
Characterization of the intrarenal renin-angiotensin system in cats with naturally occurring chronic kidney disease. Journal of veterinary internal medicine, 2022, Volume: 36, Issue:2 Topics: Angiotensin II; Animals; Cat Diseases; Cats; Kidney; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System	2022
Reduction of anaerobic glycolysis contributes to angiotensin II-induced podocyte injury with foot process effacement. Kidney international, 2023, Volume: 103, Issue:4 Topics: Anaerobiosis; Angiotensin II; Animals; Diabetic Nephropathies; Glycolysis; Mice; Podocytes; Pyruvate Kinase; Renal Insufficiency, Chronic	2023
Low-Dose Erythropoietin Amplifies Beneficial Effects of Angiotensin II Blockade on Glomerulosclerosis. Laboratory investigation; a journal of technical methods and pathology, 2023, Volume: 103, Issue:2 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Creatinine; Endothelial Cells; Erythropoietin; Mice; Proto-Oncogene Proteins c-akt; Renal Insufficiency, Chronic; Vascular Endothelial Growth Factor A	2023
PFKFB3 downregulation aggravates Angiotensin II-induced podocyte detachment. Renal failure, 2023, Volume: 45, Issue:1 Topics: Angiotensin II; Animals; Down-Regulation; Mice; Phosphofructokinase-2; Phosphorylation; Podocytes; Renal Insufficiency, Chronic	2023
Tubular injury triggers podocyte dysfunction by β-catenin-driven release of MMP-7. JCI insight, 2019, 12-19, Volume: 4, Issue:24 Topics: Angiotensin II; Animals; beta Catenin; Cells, Cultured; Disease Models, Animal; Doxorubicin; Humans; Kidney Tubules; Male; Matrix Metalloproteinase 7; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Podocytes; Primary Cell Culture; Proteolysis; Rats; Renal Insufficiency, Chronic	2019
Mechanisms of Metabolic Acidosis-Induced Kidney Injury in Chronic Kidney Disease. Journal of the American Society of Nephrology : JASN, 2020, Volume: 31, Issue:3 Topics: Acid-Base Equilibrium; Acidosis; Adaptation, Physiological; Aldosterone; Angiotensin II; Biomarkers; Disease Progression; Endothelin-1; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Male; Prospective Studies; Renal Insufficiency, Chronic; Retrospective Studies; Risk Assessment; Severity of Illness Index; Time Factors; Treatment Outcome	2020
RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice. Journal of molecular medicine (Berlin, Germany), 2020, Volume: 98, Issue:4 Topics: Angiotensin II; Animals; Biomarkers; Biopsy; Cytokines; DEAD Box Protein 58; Disease Susceptibility; Fibroblasts; Fibrosis; Gene Silencing; Immunohistochemistry; Inflammation Mediators; Interleukin-1beta; Male; Mice; Proto-Oncogene Proteins c-myc; Renal Insufficiency, Chronic; Smad Proteins; Transforming Growth Factor beta; Ureteral Obstruction	2020
Critical Role of Neprilysin in Kidney Angiotensin Metabolism. Circulation research, 2020, 08-14, Volume: 127, Issue:5 Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Case-Control Studies; Chymases; Enzyme Inhibitors; Female; Humans; Kidney; Male; Mice, Inbred C57BL; Middle Aged; Neprilysin; Peptide Fragments; Renal Insufficiency, Chronic; Renin-Angiotensin System	2020
The CX3CL1/CX3CR1 axis is upregulated in chronic kidney disease and contributes to angiotensin II-induced migration of vascular smooth muscle cells. Microvascular research, 2020, Volume: 132 Topics: Angiotensin II; Animals; Aorta; Cell Line; Cell Movement; Chemokine CX3CL1; CX3C Chemokine Receptor 1; Disease Models, Animal; Interleukin-6; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Proto-Oncogene Proteins c-akt; Renal Insufficiency, Chronic; Signal Transduction; Up-Regulation; Uremia	2020
Sirt6 deficiency aggravates angiotensin II-induced cholesterol accumulation and injury in podocytes. Theranostics, 2020, Volume: 10, Issue:16 Topics: Adult; Angiotensin II; Animals; Anticholesteremic Agents; Biopsy; Case-Control Studies; Cell Line; Cholesterol; Datasets as Topic; Disease Models, Animal; Female; Gene Expression Profiling; Humans; Lipid Metabolism; Male; Mice; Mice, Knockout; Middle Aged; Oligonucleotide Array Sequence Analysis; Podocytes; Renal Insufficiency, Chronic; Sirtuins	2020
Alteration and association between serum ACE2/ angiotensin(1-7)/Mas axis and oxidative stress in chronic kidney disease: A pilot study. Medicine, 2020, Jul-31, Volume: 99, Issue:31 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Angiotensin I; Angiotensin II; Case-Control Studies; Female; Humans; Male; Middle Aged; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Pilot Projects; Renal Insufficiency, Chronic; Renin-Angiotensin System	2020
Urinary DPP4 correlates with renal dysfunction, and DPP4 inhibition protects against the reduction in megalin and podocin expression in experimental CKD. American journal of physiology. Renal physiology, 2021, 03-01, Volume: 320, Issue:3 Topics: Angiotensin II; Animals; Biomarkers; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Fibrosis; Intracellular Signaling Peptides and Proteins; Kidney; Low Density Lipoprotein Receptor-Related Protein-2; Male; Membrane Proteins; Proteinuria; Rats, Wistar; Renal Insufficiency, Chronic; Retinol-Binding Proteins, Plasma; Signal Transduction; Sitagliptin Phosphate	2021
Angiotensin II type 1a receptor loss ameliorates chronic tubulointerstitial damage after renal ischemia reperfusion. Scientific reports, 2021, 01-13, Volume: 11, Issue:1 Topics: Angiotensin II; Animals; Blood Pressure; Hydralazine; Ischemia; Kidney; Male; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1; Renal Insufficiency, Chronic; Reperfusion	2021
Renoprotective Effects of Small Interfering RNA Targeting Liver Angiotensinogen in Experimental Chronic Kidney Disease. Hypertension (Dallas, Tex. : 1979), 2021, 05-05, Volume: 77, Issue:5 Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Arterial Pressure; Captopril; Disease Models, Animal; Kidney; Liver; Losartan; Rats; Renal Insufficiency, Chronic; Renin-Angiotensin System; RNA, Small Interfering	2021
β-Aminoisobutyric acid ameliorates the renal fibrosis in mouse obstructed kidneys via inhibition of renal fibroblast activation and fibrosis. Journal of pharmacological sciences, 2017, Volume: 133, Issue:4 Topics: Aminoisobutyric Acids; Angiotensin II; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Fibrosis; Interleukin-17; Kidney; Male; Rats, Sprague-Dawley; Reactive Oxygen Species; Renal Insufficiency, Chronic; Signal Transduction	2017
c-Myc promotes renal fibrosis by inducing integrin αv-mediated transforming growth factor-β signaling. Kidney international, 2017, Volume: 92, Issue:4 Topics: Angiotensin II; Animals; Extracellular Matrix; Fibroblasts; Fibrosis; Folic Acid; Integrin alphaV; Kidney; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-myc; Renal Insufficiency, Chronic; Signal Transduction; Thiazoles; Transforming Growth Factor beta; Up-Regulation; Ureteral Obstruction	2017
Treatment with enalapril and not diltiazem ameliorated progression of chronic kidney disease in rats, and normalized renal AT1 receptor expression as measured with PET imaging. PloS one, 2017, Volume: 12, Issue:5 Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Diltiazem; Disease Progression; Enalapril; Gene Expression Regulation; Heart; Kidney; Male; Organ Size; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Regional Blood Flow; Renal Insufficiency, Chronic	2017
Angiotensin II induces cholesterol accumulation and injury in podocytes. Scientific reports, 2017, 09-06, Volume: 7, Issue:1 Topics: Angiotensin II; Animals; Apoptosis; Cholesterol; Cytoskeleton; Disease Models, Animal; Gene Expression; Lipid Metabolism; Perilipin-2; Podocytes; Renal Insufficiency, Chronic; Simvastatin	2017
Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:1 Topics: Actins; Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Movement; Cells, Cultured; Disease Models, Animal; Genotype; Hypertension; Male; Mice; Mutation, Missense; Myosin Heavy Chains; Nephrectomy; Nonmuscle Myosin Type IIA; Podocytes; Primary Cell Culture; Renal Insufficiency, Chronic; Sodium Chloride, Dietary; Stress Fibers; Tetrazoles	2018
Adiponectin attenuates kidney injury and fibrosis in deoxycorticosterone acetate-salt and angiotensin II-induced CKD mice. American journal of physiology. Renal physiology, 2018, 09-01, Volume: 315, Issue:3 Topics: Adiponectin; Angiotensin II; Animals; Cell Proliferation; Desoxycorticosterone Acetate; Disease Models, Animal; Fibrosis; Hepatitis A Virus Cellular Receptor 1; Kidney; Lipocalin-2; Low Density Lipoprotein Receptor-Related Protein-2; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidase 2; NADPH Oxidases; Nephrectomy; Receptors, Cell Surface; Renal Insufficiency, Chronic; Signal Transduction; Transcription Factor RelA; Up-Regulation	2018
Effect of a SGLT2 inhibitor on the systemic and intrarenal renin-angiotensin system in subtotally nephrectomized rats. Journal of pharmacological sciences, 2018, Volume: 137, Issue:2 Topics: Administration, Oral; Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Glucosides; Glycosuria; Indoles; Kidney; Male; Nephrectomy; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors	2018
A blockade of PI3Kγ signaling effectively mitigates angiotensin II-induced renal injury and fibrosis in a mouse model. Scientific reports, 2018, Jul-20, Volume: 8, Issue:1 Topics: Angiotensin II; Animals; Cell Proliferation; Class Ib Phosphatidylinositol 3-Kinase; Cytokines; Disease Models, Animal; Fibroblasts; Fibrosis; Kidney; Mice; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Quinoxalines; Renal Insufficiency, Chronic; Thiazolidinediones	2018
Adiponection, a novel player to save the kidneys. American journal of physiology. Renal physiology, 2018, Nov-01, Volume: 315, Issue:5 Topics: Acetates; Adiponectin; Angiotensin II; Animals; Desoxycorticosterone Acetate; Fibrosis; Mice; Renal Insufficiency, Chronic	2018
Effects of Resveratrol on the Renin-Angiotensin System in the Aging Kidney. Nutrients, 2018, Nov-12, Volume: 10, Issue:11 Topics: Albuminuria; Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Collagen Type IV; Fibronectins; Fibrosis; Kidney; Male; Mice, Inbred C57BL; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Plant Extracts; Proto-Oncogene Proteins; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Renal Insufficiency, Chronic; Renin-Angiotensin System; Resveratrol; Superoxide Dismutase	2018
The miRNA-184 drives renal fibrosis by targeting HIF1AN in vitro and in vivo. International urology and nephrology, 2019, Volume: 51, Issue:3 Topics: Actins; Angiotensin II; Animals; Cell Line; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Databases, Genetic; Disease Models, Animal; Fibroblasts; Fibrosis; Humans; Kidney; Mice; MicroRNAs; Mixed Function Oxygenases; Rats; Renal Insufficiency, Chronic; RNA, Messenger; Ureteral Obstruction	2019
Rivaroxaban, a Direct Factor Xa Inhibitor, Ameliorates Hypertensive Renal Damage Through Inhibition of the Inflammatory Response Mediated by Protease-Activated Receptor Pathway. Journal of the American Heart Association, 2019, 04-16, Volume: 8, Issue:8 Topics: Albuminuria; Angiotensin II; Animals; Blood Coagulation; Factor Xa Inhibitors; Gene Knockdown Techniques; Glomerular Basement Membrane; Glomerular Mesangium; Humans; Hypertension; In Vitro Techniques; Inflammation; Kidney Glomerulus; Male; Mice; Mice, Transgenic; Podocytes; Receptor, PAR-2; Renal Insufficiency, Chronic; Renin; Reverse Transcriptase Polymerase Chain Reaction; Rivaroxaban; Vasoconstrictor Agents	2019
Cardioprotection Conferred by Sitagliptin Is Associated with Reduced Cardiac Angiotensin II/Angiotensin-(1-7) Balance in Experimental Chronic Kidney Disease. International journal of molecular sciences, 2019, Apr-20, Volume: 20, Issue:8 Topics: Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Pressure; Body Weight; Cardiotonic Agents; Diastole; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Kidney; Kidney Function Tests; Male; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Rats, Wistar; Renal Insufficiency, Chronic; Renin-Angiotensin System; Sitagliptin Phosphate; Up-Regulation; Ventricular Remodeling	2019
Adiponectin attenuates angiotensin II-induced oxidative stress in renal tubular cells through AMPK and cAMP-Epac signal transduction pathways. American journal of physiology. Renal physiology, 2013, Jun-01, Volume: 304, Issue:11 Topics: Adiponectin; AMP-Activated Protein Kinases; Angiotensin II; Cells, Cultured; Cyclic AMP; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Fibronectins; Gene Expression; Guanine Nucleotide Exchange Factors; Humans; Kidney Tubules, Proximal; NADPH Oxidases; NF-kappa B; Oxidative Stress; Pyrazoles; Pyrimidines; Receptors, Adiponectin; Renal Insufficiency, Chronic; Renin-Angiotensin System; Signal Transduction	2013
Periaortic adipose tissue-specific activation of the renin-angiotensin system contributes to atherosclerosis development in uninephrectomized apoE-/- mice. American journal of physiology. Heart and circulatory physiology, 2013, Sep-01, Volume: 305, Issue:5 Topics: Adipocytes; Adipose Tissue; Angiotensin II; Angiotensinogen; Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Cholesterol, Dietary; Disease Models, Animal; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; PPAR gamma; Renal Insufficiency, Chronic; Renin-Angiotensin System	2013
Protective effects of angiotensin-(1-7) administrated with an angiotensin-receptor blocker in a rat model of chronic kidney disease. Nephrology (Carlton, Vic.), 2013, Volume: 18, Issue:12 Topics: Angiopoietins; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Fibronectins; Losartan; Male; Nephrectomy; Peptide Fragments; Plasminogen Activator Inhibitor 1; Rats, Sprague-Dawley; Receptor, TIE-2; Renal Insufficiency, Chronic; Systole	2013
ELISA examining urinary angiotensinogen as a potential indicator of intrarenal renin-angiotensin system (RAS) activity: a clinical study of 128 chronic kidney disease patients. Molecular biology reports, 2013, Volume: 40, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensinogen; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Regression Analysis; Renal Insufficiency, Chronic; Renin-Angiotensin System; Young Adult	2013
Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. Clinical and experimental pharmacology & physiology, 2014, Volume: 41, Issue:3 Topics: Angiotensin II; Animals; Blood Pressure; Epoxide Hydrolases; Female; Hypertension; Nephrectomy; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renal Insufficiency, Chronic; Survival Rate	2014
Urinary angiotensinogen as a potential biomarker of intrarenal renin-angiotensin system activity in Chinese chronic kidney disease patients. Irish journal of medical science, 2015, Volume: 184, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Angiotensinogen; Asian People; Biomarkers; China; Collagen Type IV; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Receptors, Angiotensin; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Young Adult	2015
Tumor necrosis factor-α produced in the kidney contributes to angiotensin II-dependent hypertension. Hypertension (Dallas, Tex. : 1979), 2014, Volume: 64, Issue:6 Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Renal Insufficiency, Chronic; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents	2014
SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis. Journal of the American Society of Nephrology : JASN, 2015, Volume: 26, Issue:8 Topics: Angiotensin II; Animals; Cells, Cultured; Endoplasmic Reticulum Stress; ErbB Receptors; Fibronectins; Fibrosis; Intracellular Signaling Peptides and Proteins; Kidney; Male; Membrane Proteins; Mesangial Cells; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Rats, Inbred Dahl; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Insufficiency, Chronic; Serine Proteases; Sp1 Transcription Factor; Sterol Regulatory Element Binding Protein 1; Thiazoles; Transforming Growth Factor beta1; Up-Regulation	2015
The effect of losartan on differential reflex control of sympathetic nerve activity in chronic kidney disease. Journal of hypertension, 2015, Volume: 33, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autonomic Pathways; Baroreflex; Kidney; Losartan; Lumbosacral Region; Male; Nitroprusside; Phenylephrine; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Renal Insufficiency, Chronic; Sympathetic Nervous System	2015
Identification of the Vasoconstriction-Inhibiting Factor (VIF), a Potent Endogenous Cofactor of Angiotensin II Acting on the Angiotensin II Type 2 Receptor. Circulation, 2015, Apr-21, Volume: 131, Issue:16 Topics: Adrenal Glands; Amino Acid Sequence; Angiotensin II; Animals; Cattle; Cells, Cultured; Chromogranin A; Endothelial Cells; Heart Failure; Humans; Male; MAP Kinase Signaling System; Mice; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Peptides; Protein Processing, Post-Translational; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Angiotensin, Type 2; Renal Insufficiency, Chronic; Renin-Angiotensin System; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Vasodilation	2015
Systemic Aldosterone, But Not Angiotensin II, Plays a Pivotal Role in the Pathogenesis of Renal Injury in Chronic Nitric Oxide-Deficient Male Rats. Endocrinology, 2015, Volume: 156, Issue:7 Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Chemokine CCL2; Disease Models, Animal; Enzyme Inhibitors; Kidney; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Osteopontin; Rats; Renal Insufficiency, Chronic; Renin-Angiotensin System; RNA, Messenger; Time Factors; Transforming Growth Factor beta1	2015
Elevated Endothelial Hypoxia-Inducible Factor-1α Contributes to Glomerular Injury and Promotes Hypertensive Chronic Kidney Disease. Hypertension (Dallas, Tex. : 1979), 2015, Volume: 66, Issue:1 Topics: Angiotensin II; Animals; Antigens, CD; Cadherins; Cells, Cultured; Disease Progression; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Feedback, Physiological; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Glomerulus; Mice; Mice, Transgenic; NF-kappa B; Organ Culture Techniques; Renal Insufficiency, Chronic; RNA, Small Interfering; Up-Regulation	2015
Development of a Model of Chronic Kidney Disease in the C57BL/6 Mouse with Properties of Progressive Human CKD. BioMed research international, 2015, Volume: 2015 Topics: Angiotensin II; Animals; Desoxycorticosterone Acetate; Disease Models, Animal; Disease Progression; Female; Humans; Male; Mice; Renal Insufficiency, Chronic	2015
Renin-angiotensin blockade resets podocyte epigenome through Kruppel-like Factor 4 and attenuates proteinuria. Kidney international, 2015, Volume: 88, Issue:4 Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Line; Disease Models, Animal; DNA Methylation; Dose-Response Relationship, Drug; Doxorubicin; Epigenesis, Genetic; Irbesartan; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Podocytes; Promoter Regions, Genetic; Renal Insufficiency, Chronic; Renin-Angiotensin System; Signal Transduction; Tetrazoles; Time Factors; Transfection	2015
Th-17 cell activation in response to high salt following acute kidney injury is associated with progressive fibrosis and attenuated by AT-1R antagonism. Kidney international, 2015, Volume: 88, Issue:4 Topics: Acute Kidney Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Cytoprotection; Disease Models, Animal; Disease Progression; Fibrosis; Kidney; Losartan; Lymphocyte Activation; Male; Nephrectomy; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Renin-Angiotensin System; Sodium Chloride, Dietary; Th17 Cells; Time Factors	2015
Antagonism of scavenger receptor CD36 by 5A peptide prevents chronic kidney disease progression in mice independent of blood pressure regulation. Kidney international, 2016, Volume: 89, Issue:4 Topics: Angiotensin II; Animals; Blood Pressure; CD36 Antigens; Chemokine CXCL1; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Fibrosis; Fluorescent Dyes; HeLa Cells; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-1beta; Interleukin-6; Kidney; Male; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; NLR Family, Pyrin Domain-Containing 3 Protein; Peptides; Renal Insufficiency, Chronic; Ureteral Obstruction	2016
Specific endothelial heparin-binding EGF-like growth factor deletion ameliorates renal injury induced by chronic angiotensin II infusion. American journal of physiology. Renal physiology, 2016, 10-01, Volume: 311, Issue:4 Topics: Albuminuria; Angiotensin II; Animals; Endothelium, Vascular; ErbB Receptors; Glomerulosclerosis, Focal Segmental; Heparin-binding EGF-like Growth Factor; Kidney; Mice; Mice, Knockout; Phosphorylation; Renal Insufficiency, Chronic	2016
Endoplasmic reticulum stress inhibition attenuates hypertensive chronic kidney disease through reduction in proteinuria. Scientific reports, 2017, 02-02, Volume: 7 Topics: Angiotensin II; Animals; Apoptosis; Biopsy; Blood Pressure; Disease Models, Animal; Endoplasmic Reticulum Stress; Fibrosis; Gene Expression Profiling; Humans; Hypertension; Inflammation; Male; Mice; Mice, Knockout; Nephrosclerosis; Phenylbutyrates; Proteinuria; Renal Insufficiency, Chronic; Transcription Factor CHOP; Transcriptome; Urinalysis	2017
FTY720 Attenuates Angiotensin II-Induced Podocyte Damage via Inhibiting Inflammatory Cytokines. Mediators of inflammation, 2017, Volume: 2017 Topics: Adult; Angiotensin II; Animals; Cell Adhesion; Enzyme-Linked Immunosorbent Assay; Female; Fingolimod Hydrochloride; Humans; Immunohistochemistry; Interleukin-6; Lysophospholipids; Male; Middle Aged; Podocytes; Radioimmunoassay; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Renal Insufficiency, Chronic; Sphingosine; Tumor Necrosis Factor-alpha; Wound Healing; Young Adult	2017
IL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting. Journal of the American Society of Nephrology : JASN, 2009, Volume: 20, Issue:3 Topics: Angiotensin II; Animals; Cell Line; Humans; Insulin Receptor Substrate Proteins; Interleukin-6; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Fibers, Skeletal; Muscular Atrophy; Proto-Oncogene Proteins c-akt; Rats; Receptors, Angiotensin; Recombinant Proteins; Renal Insufficiency, Chronic; Serum Amyloid A Protein; Suppressor of Cytokine Signaling Proteins; Wasting Syndrome	2009
Renoprotective effect of Tanshinone IIA, an active component of Salvia miltiorrhiza, on rats with chronic kidney disease. Phytotherapy research : PTR, 2010, Volume: 24, Issue:12 Topics: Abietanes; Administration, Oral; Angiotensin II; Animals; Collagen Type IV; Creatinine; Disease Models, Animal; Drugs, Chinese Herbal; Kidney; Male; Phenanthrenes; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Salvia miltiorrhiza; Transforming Growth Factor beta1	2010
Interleukin 6 underlies angiotensin II-induced hypertension and chronic renal damage. Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:1 Topics: Adult; Angiotensin II; Animals; Biopsy; Blood Pressure; Disease Progression; Endothelin-1; Female; Fibrosis; Humans; Hypertension, Renal; Interleukin-6; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Middle Aged; Organ Culture Techniques; Proteinuria; Renal Insufficiency, Chronic; Signal Transduction; Vasoconstrictor Agents	2012
AT1 antagonism and renin inhibition in mice: pivotal role of targeting angiotensin II in chronic kidney disease. American journal of physiology. Renal physiology, 2012, Volume: 303, Issue:7 Topics: Albuminuria; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Dose-Response Relationship, Drug; Fumarates; Gene Expression; Kidney; Losartan; Male; Mice; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Treatment Outcome	2012
An increase in perfusion pressure and activation of the renin-angiotensin system in the pathogenesis of hypertension and injury: strain vessels and the cerebrovascular-renal connection. Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:10 Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Blood Pressure; Cerebrovascular Circulation; Humans; Hypertension; Kidney; Rats; Renal Circulation; Renal Insufficiency, Chronic; Renin-Angiotensin System	2012
Association between the intrarenal renin-angiotensin system and renal injury in chronic kidney disease of dogs and cats. The Journal of veterinary medical science, 2013, Volume: 75, Issue:2 Topics: Angiotensin II; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Kidney; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System	2013
Ang II induce kidney damage by recruiting inflammatory cells and up regulates PPAR gamma and Renin 1 gene: effect of β carotene on chronic renal damage. Journal of thrombosis and thrombolysis, 2013, Volume: 36, Issue:3 Topics: Angiotensin II; Animals; Apolipoproteins E; beta Carotene; Cell Movement; Female; Inflammation; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Mice; Mice, Knockout; Polycystic Kidney Diseases; PPAR gamma; Renal Insufficiency, Chronic; Renin	2013
Beyond the RAAS: dissecting the antifibrotic effects of vitamin D analogues. Laboratory investigation; a journal of technical methods and pathology, 2012, Volume: 92, Issue:12 Topics: Angiotensin II; Animals; Fibrosis; Humans; Kidney; Mice; Mice, Knockout; Protective Agents; Renal Insufficiency, Chronic; Renin-Angiotensin System; Vitamin D	2012